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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Characterization of goat whey proteins and their bioactivity and toxicity assay显示文摘Goat whey is an industry-discarded dairy by-product that has interesting nutritional value and a nutrient composition with important functional potential,where proteins have a high biological value and play an important role in the organism’s physiology.Therefore,the aim of this study was to identify,quantify,concentrate and investigate the capacity of goat whey proteins to perform different biological activities and to evaluate their acute toxicity.Concentrated proteins were quantified and identified by Bradford,Kjehdal and SDS-PAGE methods.Antibacterial activity was performed against Listeria monocytogenes,Salmonella spp.,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli microorganisms and showed MIC ranging from 15 to 120μg mL-1,with the highest inhibition for L.monocytogenes growth.Antiproliferative activity was performed against human malignant melanoma cells and their proliferation inhibition was up to 66.8%within 72 h of exposure.The highest antioxidant capacity was obtained at concentration 2 mg that showed 29.69%of inhibition of DPPH radical oxidation.The acute toxicity test was performed using Artemia franciscana larvae in which whey proteins were able to preserve larval survival throughout exposure.Thus,we can conclude that goat’s whey has proteins that can play a positive effect on health,with antimicrobial activity and without toxicity.The present study highlights the great potential of goat’s whey to be developed as a safe biopreservative or as a functional ingredient in the food industry. | Maria Isabel Ferreira Campos Paula Perazzo de Souza Barbosa Laura Junqueira Camargo Luciano Da Silva Pinto Bianca Mataribu Catarina Serr˜ao Luis Fernando Marques-Santos Jos´e Hon´orio Lopes Julia Mariano Caju de Oliveira Carlos Alberto de Almeida Gadelha Tatiane Santi-Gadelha | 2022 | Food Bioscience2022，46，2： | 2 |
| 3 | 金龟子绿僵菌分生孢子暴露在B段紫外光下毒力的降低显示文摘The UV-A and UV-B wavelengths of solar radiation may seriously reduce viability of Metarhizium anisopliae conidia,a fungus used extensively in Brazil for insect pest control.The conidial tolerances to UV-A and UV-B radiation were studied for one isolate(IBCB 425) commercially available product produced on rice grains.Aqueous or oil emulsion conidial suspensions were irradiated for 0(control),2,or 3 h using the solar simulator filtered with diacetate filter to remove UV-C radiation which afforded 652 mW·m-2 in the spectral range of 280~370 nm.The UV tolerance was based on conidial germination(viability) and virulence to Diatraea saccharalis larvae.Conidia formulated with oil emulsion had higher survival after 3 h of UV exposure,but the virulence of the conidia previously exposed to 2 h of UV radiation were similar when oil formulated or not.The mortality of D.saccharalis caterpillars exposed to non-UV-irradiated conidia was greater than that of larvae exposed to irradiated conidia,and the LT50 values were lower for the non-irradiated suspensions than for those irradiated.This apparent reduction in virulence was directly related reduction in viability or delay of germination of UV-irradiated conidia. | Edimara A Francisco Drauzio E N Rangel Newton La Scala Jr José C Barbosa Antnia do C B Correia | 2008 | 安徽农业大学学报2008，35，2： | 2 |
| 4 | Sonographic hepatorenal ratio: A noninvasive method to diagnose nonalcoholic steatosis显示文摘 | Valéria Ferreira de Almeida e Borges Angélica L. D. Diniz Helma P. Cotrim Haroldo L. O. G. Rocha Nestor Barbosa Andrade | 2012 | J Clin Ultrasound2012，，1： | 2 |
| 5 | Stability analysis and improvement of structural index estimation in Euler deconvolution显示文摘 | Barbosa V C F Silva J B C Medeiros W E | 1999 | Geophysics1999，64，1： | 1 |
| 6 | Comparison betweencapillary electrophoresis,liquid chromatography,potentiometric andspectrophotometric techniques for evaluation of pKa values ofzwitterionic drugs in acetonitrile-water mixtures显示文摘 | Barbosa J Barron D Jimenez-Lozano E | | AnalyticaChimica Acta0，1437，： | 1 |
| 7 | Characterization of a cloned cDNA encoding rabbit myelin P2 protein显示文摘 | Barbosa E Reed R | 1995 | J Biol Chem1995，263，： | 1 |
| 8 | Making Euler deconvolution applicable to small ground magnetic surveys显示文摘 | Valéria C F Barbosa Joao B C Silva Walter E Medeiros | 2000 | Journal of Applied Geophysics2000，43，1： | 1 |
| 9 | Polypropylene/Polystyrene Blends: In Situ Compatibilization by Friedel-Crafts Alkylation Reaction 显示文摘 | Diaz M F Barbosa S E Capiati N | 2004 | Journal of Polymer Science: Part B: Polymer Physics2004，42，： | 1 |
| 10 | Robust H2 filtering for uncertain linear systems:LMI based methods with parametric Lyapunov functions显示文摘 | Barbosa K A De Souza C E Trofino A | 2005 | Systems and Control Letters2005，54，3： | 1 |
| 11 | Computational anal- ysis of thoracic multideteetor row HRCT for segmentation and quantification of small airway air trapping and emphysema in ob- structive pulmonary disease 显示文摘 | Barbosa E M Jr Song G Tustison N | 2011 | Acad Radiol2011，18，10： | 1 |
| 12 | Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery 显示文摘 | SOUTO E B WISSING S A BARBOSA C M | 2004 | Int J Pharm2004，278，1： | 1 |
| 13 | Electrochemical and surface modifications on N+-ion-implanted 316L stainless steel 显示文摘 | LEITAO E SILIVA R A BARBOSA M | 1997 | J Mater Sci Mater Med1997，8，： | 1 |
| 14 | Expansion of high flow mixtures of gypsum bonded investments in contact with absorbent liners显示文摘 | Edmea Lodovici J osete Barbosa Cruz Meira Leonardo Eloy Rodrigues Filho and Rafael Yagüe Ballester | 2005 | Dental Materials2005，06，57： | 1 |
| 15 | Mapping substrate/film adhesion with contact resonance-frequency atomic force mi croscopy 显示文摘 | Hurley D C Kopycinska Muller M Langlois E D Kos A B Barbosa N | 2006 | Applied Physics Letters2006，89，02： | 1 |
| 16 | Anterior vocal commissure invasion in laryngeal carcinoma diagnosis 显示文摘 | BARBOSA M M ARAUJO V J JR BOASQUEVISQUE E | 2005 | Laryngoscope2005，115，4： | 1 |
| 17 | Infiltration pond design for highway runoff treatment in semiarid climates 显示文摘 | Barbosa A E Hvitved J T | 2001 | Journal of Environmental Engineering2001，127，11： | 1 |
| 18 | Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats 显示文摘 | Pannu R Barbosa E Singh AK et aI | 2005 | J Neurosci Res2005，79，3： | 1 |
| 19 | An adaptive con- straint handling technique for differential evolution with dynamic use of variants in engineering optimization 显示文摘 | E K Silva H J C Barbosa A C C Lemonge | 2011 | Optimization and Engineering2011，12，12： | 1 |
| 20 | Dynamics of natural gas adsorption storage systems employing activated carbon显示文摘 | BARBOSA MOTA J P RODRIGUES A E | 1997 | Carbon1997，35，9： | 1 |
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