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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Clinical hematological and biochemical parameters in Swiss,BALB/c,C57BL/6 and B6D2F1 Mus musculus显示文摘Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental conditions.Various lineages of mice have been used to investigate diseases and new therapeutic strategies,and,consequently,hematological and biochemical tests in these laboratory animals are essential to validate scientific studies.Our study seeks to establish reference values for hematological and biochemical parameters of four lineages of mice.Methods:We evaluated the hematological and biochemical profiles of 20 males and 20 females from the lineages Swiss(heterogeneous),BALB/c and C57BL/6(isogenic),and B6D2F1(hybrid),totaling 160 mice.Analysis were standardized using the systems pocH-100iV Diff™for 19 hematological parameters and VITROS®350 for 12 biochemical parameters.Results:Results are shown as means and standard deviation,grouped by lineage and genre.Comparing the values obtained in this study with the values from previous studies,some variations were detected,which could be explained by differences in methodologies or individual variability.Conclusion:Thus our study shows that knowledge and disclosure of the values of physiological parameters of laboratory animals is necessary,and emphasises the importance of considering variations influenced by gender,lineage and genotype in the choice of the best experimental model. | Giorgio Silva-Santana Juliet Cunha Bax Débora Cristina Silva Fernandes Daniela Tendler Leibel Bacellar Cleber Hooper Alexandre Alves Souza Oliveira Dias Cristina Barbosa Silva Aline Moreira de Souza Simone Ramos Ricardo Alexandre Santos Thainara Ramos Pinto Mariana Antunes Ramão Ana Luíza Mattos-Guaraldi | 2020 | Animal Models and Experimental Medicine2020，3，4： | 2 |
| 3 | Comparison betweencapillary electrophoresis,liquid chromatography,potentiometric andspectrophotometric techniques for evaluation of pKa values ofzwitterionic drugs in acetonitrile-water mixtures显示文摘 | Barbosa J Barron D Jimenez-Lozano E | | AnalyticaChimica Acta0，1437，： | 1 |
| 4 | Mechanical behavior and microstructure of high carbon Si- Mn- Cr steel with TRIP effect 显示文摘 | SANTOS D B BARBOSA R De OLIVEIRA P P | 2009 | ISH International2009，49，10： | 1 |
| 5 | Hepatic photosensitization in buffaloes intoxicated by Bra- chiaria decumbens in Minas Gerais state, Brazil显示文摘 | De Oliveira C H S Barbosa J D Oiiveira C M C | 2013 | Toxi- con2013，73，： | 1 |
| 6 | Automatic small bowel tumor diagnosis by u?sing multi-scale wavelet-based analysis in wireless cap?sule endoscopy images显示文摘 | Barbosa D C Roupar D B RamosJ C Tavares A C Li?rna C S | 2012 | Biomed Eng Online2012，11，： | 1 |
| 7 | Hydrogen sulphide removal by activated sludge diffusion 显示文摘 | Barbosa V L Dufol D Callan J L | 2004 | Water Science and Technology2004，50，4： | 1 |
| 8 | Botulinum toxin:mechanisms of action显示文摘 | Dressler D Saberi FA Barbosa ER | | 0，，： | 1 |
| 9 | The relevance of the procedures related to the physiotherapy in the interventions in pa- tients with prostate cancer: short review with practice approach 显示文摘 | Bemardo- Filho M Barbosa Jnior ML da Cunha S-Caputo D | 2014 | Int J BiomedSci2014，，2： | 1 |
| 10 | Effects of the vitamin E in catalase activities in hippocampus after status epi- lepticus induced by pilocarpine in wistar rats显示文摘 | Barros D O Xavier S M L Barbosa C O etal | 2007 | Neuroscencei Letters2007，416，3： | 1 |
| 11 | Synthesis and characterisation of materials based on inorganic polymers of alumina and silica: sodium polysialate polymers 显示文摘 | Barbosa J D MacKenzie K Thaumaturgo C | 2000 | International Journal of Inorganic Materials2000，，2： | 1 |
| 12 | Synthesis and thermal behavior of potassium sialate geopolymers显示文摘 | Barbosa V F F MacKenzie K J D | 2003 | Materials Letters2003，57，： | 1 |
| 13 | Abnormal uterine bleeding as a presenting symptom is related to multiple uterine leiomyoma : an ultrasound - based study 显示文摘 | FONSECA MOUTINHO J A BARBOSA L S TORRES D G | 2013 | Int J Womens Health2013，18，5： | 1 |
| 14 | Mapping substrate/film adhesion with contact resonance-frequency atomic force mi croscopy 显示文摘 | Hurley D C Kopycinska Muller M Langlois E D Kos A B Barbosa N | 2006 | Applied Physics Letters2006，89，02： | 1 |
| 15 | When does quality of life improve after liver transplantation? a longitudinal prospective study 显示文摘 | Telles-Correia D Barbosa A Mega I | 2009 | Transplant Proc2009，41，3： | 1 |
| 16 | Optimization of laccase production by Botryosphaeria sp in the presence of veratryl alcohol by the response-surface method显示文摘 | VASCONCELOS A F D BARBOSA A M DEKKER R F H | 2000 | Process Biochemistry2000，35，10： | 1 |
| 17 | Characterization of metal/mould interface on investment casting of γ-TiAl显示文摘 | BARBOSA J PUGA H RIBEIRO C S TEODORO O M N D MONTEIRO A C | 2006 | International Journal of Cast Metals Research2006，19，6： | 1 |
| 18 | Mathematical characterization of three-dimensional gene expression patterns 显示文摘 | COSTA L D F BARBOSA M S MANOEL E T M | 2004 | Bioinformatics2004，20，11： | 1 |
| 19 | Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil显示文摘 | POURIA S ANDRADE A D BARBOSA J | 1998 | The Lancet1998，352，3： | 1 |
| 20 | Detemaination of CA and Pb in food slurries by GFAAS using cryogenic grinding for sample preparation显示文摘 | SANTOS D J BARBOSA F J TOMAZELLI A C | 2002 | Anal Biochem2002，373，3： | 1 |
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