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| 1 | New challenges in perioperative management of pancreatic cancer显示文摘Pancreatic ductal adenocarcinoma(PDAC)is the fourth leading cause of cancer-related death in the industrialized world.Despite progress in the understanding of the molecular and genetic basis of this disease,the5-year survival rate has remained low and usually does not exceed 5%.Only 20%-25%of patients present with potentially resectable disease and surgery represents the only chance for a cure.After decades of gemcitabine hegemony and limited therapeutic options,more active chemotherapies are emerging in advanced PDAC,like 5-Fluorouracil,folinic acid,irinotecan and oxaliplatin and nab-paclitaxel plus gemcitabine,that have profoundly impacted therapeutic possibilities.PDAC is considered a systemic disease because of the high rate of relapse after curative surgery in patients with resectable disease at diagnosis.Neoadjuvant strategies in resectable,borderline resectable,or locally advanced pancreatic cancer may improve outcomes.Incorporation of tissue biomarker testing and imaging techniques into preoperative strategies should allow clinicians to identify patients who may ultimately achieve curative benefit from surgery.This review summarizes current knowledge of adjuvant and neoadjuvant treatment for PDAC and discusses the rationale for moving from adjuvant to preoperative and perioperative therapeutic strategies in the current era of more active chemotherapies and personalized medicine.We also discuss the integration of good specimen collection,tissue biomarkers,and imaging tools into newly designed preoperative and perioperative strategies. | Francesco Puleo Raphaёl Maréchal Pieter Demetter Maria-Antonietta Bali Annabelle Calomme Jean Closset Jean-Baptiste Bachet Jacques Deviere Jean-Luc Van Laethem | 2015 | World Journal of Gastroenterology2015,21,8: | 4 |
| 2 | Prognostic value of ischaemia-medified albumin in patients with non-ST-segment elevation acute coronary syndromes显示文摘 | BALI L CUISSET T GIORGI R | 2008 | Arch Cardiovasc Dis2008,101,10: | 1 |
| 3 | Methotrexate distribution within the subarachnoid space after intraventricular and intravenous administration 显示文摘 | Balis F M Blaney S M Mccully C L | 2000 | Cancer Chemoth Pharm2000,45,3: | 1 |
| 4 | Histone deacetylase Inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B显示文摘 | Fuino L Bali P Wittmann S | 2003 | Mol Cancer Ther2003,2,10: | 1 |
| 5 | Palladium thin film deposition from liquid precursors on polymers by projected excimer beams显示文摘 | Kordás K Nánai L Bali L | 2000 | Applied surface Science2000,168,: | 1 |
| 6 | IL-10 in vivo gene expression in a cell-induced animal model of proliferative vitreo-retinopathy显示文摘 | Bali E Willermain F Caspers-Velu L Dubois C Dehou MF Velu T | 2003 | Int J Mol Med2003,,3: | 1 |
| 7 | Estimating evaporation from bare soil using soil moisture data 显示文摘 | Ventura F Snyder R L Bali K M | 2006 | Journal of Irrigation and Drainage Engineering2006,132,2: | 1 |
| 8 | Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation 显示文摘 | Bali L M Bernardo M E Roelofs H | 2007 | Blood2007,110,: | 1 |
| 9 | An experimental study on heat transfer and pressure drop characteristics of decaying swirl flow through a circular pipe with a vortex generator显示文摘 | Betül Ayhan Sara? Tulin Bali | 2007 | Experimental Thermal and Fluid Science2007,,1: | 1 |
| 10 | Use of hydrogen peroxide in combination with nisin, sodium lactate and citric acid for reducing transfer of bacterial pathogens from whole melon surfaces to fresh - cut pieces 显示文摘 | Ukuku D O Bali M L Kawamoto S | 2005 | International Journal of Food Microbiology2005,104,2: | 1 |
| 11 | Effects of high doses of manganese on carbohydrate homeostasis显示文摘 | BALY D L L?NNERDAL B KEEN C L | 1985 | Toxicology Letters1985,25,1: | 1 |
| 12 | Is there a risk-return tradeoff? Evidence from high-frequency data显示文摘 | Bali T Peng L | 2006 | Journal of Applied Econometrics2006,21,8: | 1 |
| 13 | Cyelieality in Catastrophic and Operational Risk Measurements显示文摘 | Allen L Bali T G | 2007 | Journal of Banking & Finance2007,,4: | 1 |
| 14 | Prognostic value of is- chemia modified albumin in patients with non-ST-segment el- evation acute coronary syndromes 显示文摘 | BALI L CUISSET T GIORGI R | 2008 | Arch Cardiovasc Dis2008,101,10: | 1 |
| 15 | Histone deacetylase in- hibitor LAQ824 down-regulates Her-2 and sensitizes hu- man breast cancer ceils to trastuzumab, taxotere, gem- citabine, and epothilone B 显示文摘 | Fuino L Bali P Wittmann S | 2003 | Mol Cancer Ther2003,,2: | 1 |
| 16 | Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer ceils to trastuzumab, taxotere, gemcitabine, and epothilone B 显示文摘 | Fuino L Bali P Wittmann S | 2003 | Mol Cancer Ther2003,2,10: | 1 |
| 17 | Cyclin D 1, p53 and p21 Wafl/Cip 1 expression is predictive of poor clinical outcome in serous epithelial ovarian cancer显示文摘 | Bali A O'Brien P M Edwards L S | 2004 | Clin Cancer Res2004,10,15: | 1 |
| 18 | Coronary wall character- istics after myocardial infarction without significant coro- nary angiographic lesion:an intravascular ultrasound study显示文摘 | Poyet R Cuisset T Bali L et a/ | 2010 | Acta Cardiol2010,65,6: | 1 |
| 19 | Effects of high doses of man- ganese on carbohydrate homeostasis 显示文摘 | Baly D L Lonnerdal B Keen C L | 1985 | Toxicology Letters1985,25,1: | 1 |
| 20 | Prognostic value of ischaemia-modified albumin in patients with noN-ST-segment elevation acute coronary syndromes显示文摘 | Bali L Cuisset T Giorgi R | 2008 | Arch Cardiovasc Dis2008,101,10: | 1 |