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| 1 | Antimicrobial potential of selected brown seaweeds from Vedalai coastal waters,Gulf of Mannar显示文摘Objective:To evaluate the antimicrobial activity of Turbinaria conoides(T.conoides).Padina gymnospora(P.gymnospora) and Sargassum tenerrimum against human bacterial and fungal pathogens.Methods:The antimicrobial activities of the extracts against various organisms were tested by using disc diffusion method.Results:The methanol extract showed the better result than the other extracts.Whereas,the strong antibacterial inhibition was noted in methanol extracts of P.gymnospora against Bacillus subtilus(26.33±1.86) and the mild inhibition of ethanol extracts from T.conoides against Klebsiella pneumoniae(2.33±0.51).Acetone extraction of P. gymnospora had strong antifungal inhibition against Cryptococcus neoformans(23.00±1.78), and acetone extract of T.conoides had mild inhibition against Aspergillus niger(3.00±0.89). Conclusions:The seven different solvent extracts of seaweeds used in the present study have shown significant bacterial action.Further,a detailed study on the principle compound in the seaweeds which is responsible for antimicrobial activity is still needed and it can be achieved by using advanced separation techniques. | Manivannan K Karthikai devi G Anantharaman P Balasubramanian T | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 9 |
| 2 | Optimization of Friction Welding Process Parameters for Joining Carbon Steel and Stainless Steel显示文摘Friction welding is a solid state joining process used extensively currently owing to its advantages such as low heat input,high production efficiency,ease of manufacture,and environment friendliness.Materials difficult to be welded by fusion welding processes can be successfully welded by friction welding.An attempt was made to develop an empirical relationship to predict the tensile strength of friction welded AISI 1040 grade medium carbon steel and AISI 304 austenitic stainless steel,incorporating the process parameters such as friction pressure,forging pressure,friction time and forging time,which have great influence on strength of the joints.Response surface methodology was applied to optimize the friction welding process parameters to attain maximum tensile strength of the joint.The maximum tensile strength of 543 MPa could be obtained for the joints fabricated under the welding conditions of friction pressure of 90 MPa,forging pressure of 90 MPa,friction time of 6 s and forging time of 6 s. | R Paventhan P R Lakshminarayanan V Balasubramanian | 2012 | Journal of Iron and Steel Research(International)2012，19，1： | 6 |
| 3 | Hepatoprotective activity of brown alga Padina boergesenii against CCl_4 induced oxidative damage in Wistar rats显示文摘Objective:To investigate the protective effects of brown alga Padina boergesenii(P.boergeseii) against carbon tetrachloride(CCl4) induced oxidative damage and liver fibrosis in rats.Methods: To assess the hepatic damage liver weight,the activities of TBARS level,glutathione,SOD,CAT and GPx in circulation and liver.Results:The group of rats induced with CCl4 alone(2 mL/kg body weight),showed noticeable increase in the liver weight and TBARS level.Followed by, the level of antioxidant enzymes glutathione peroxidase,Superoxide dismutase and catalase was also significantly(P<0.01) diminished.Where as,the rats pretreated with P.boergesenii(150 mg/ kg body weight) modulated the CCl4 induced liver fibrosis.The level of antioxidant enzymes and lipid peroxidation products was found to be significandy(P<0.01) attenuated to near normal level, when compared with rats induced with CCL,alone.In order to assess the role of carotenoids in the relevant activity,total carotenoid content of the extract was analysed and found to be 0.59 mg/g fresh weight(FW).Further,the histopathogical studies provide a supportive evidence for this study to show the protective nature of P.boergesenii.Conclusions:The protective role of brown alga P.boergesenii extract has confirmed its potential activity through its antioxidant sparing actions against CCl4 induced free radical damage.However,the possible mechanism of hepatoprotection is rather speculative at this stage and investigations are underway to isolate and characterize the bioactive compounds from P.boergesenii. | Rajamani Karthikeyan ST Somasundaram T Manivasagam T Balasubramanian P Anantharaman | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 6 |
| 4 | Endocrine milieu and erectile dysfunction: is oestradio-testosterone imbalance, a risk factor in the elderly?显示文摘雌激素不对女性独占,但是在 25-70 的中等传播层次发生; pg 在男人的 ml −1 ,与 44-153 相比; pg 在女人的 ml −1 。从睾丸激素(T) 的 aromatisation 产生,雌激素被认为有许多在变老的男性反对生理的功能和进步 T 衰落与浆液 oestradiol 的相对或绝对的增加被联系(E 2) 。性公正和可勃起的机能障碍(编辑) 在老很可能由于 pathophysiological E 2-T 不平衡;改变的神经质的比率可以也向 environmental/plant 雌激素在 hyperestrogenism 或后面的暴露解释编辑的更高的发生。 | Balasubramanian Srilatha P Ganesan Adaikan | 2011 | Asian Journal of Andrology2011，13，4： | 5 |
| 5 | Arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia:a single center experience显示文摘 | Mathews V Balasubramanian P Shaji R V | 2002 | Am J Hematol2002，70，4： | 2 |
| 6 | Polyehlorinated biphenyl ( Aroclor 1254 ) inhibits testosterone biosynthesis and antioxidant enzymes in cultured rat Leydig cells 显示文摘 | P Murugesan T Muthusamy K Balasubramanian | 2008 | Reproductive toxicology2008，25，1： | 1 |
| 7 | RMM:a methodology for structured hypermedia design显示文摘 | Edward A Stohr P Balasubramanian | 1995 | Communications of the ACM1995，38，8： | 1 |
| 8 | Knowledgescope: managing knowledge in context 显示文摘 | Kwan M M Balasubramanian P | 2003 | Decision Support Systems2003，35，4： | 1 |
| 9 | Process-oriented knowledge management:a case study显示文摘 | MM Kwan P Balasubramanian | 2003 | Journal of the Operational Research Society2003，54，： | 1 |
| 10 | Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine显示文摘 | Cwirla S E Balasubramanian P Duffin D J | 1997 | Sci- ence1997，276，5319： | 1 |
| 11 | High frequency of type 1 B (idiopathic) diabetes in North Indian Children with recent-onset diabetes显示文摘 | Balasubramanian K Dabadghao P Bhatia V | | 0，，： | 1 |
| 12 | Combined NMR and XAS study on local environments and electronic structures of electrochemically Li-ion deintercalated Li1-xCo1/3Ni1/3Mn1/3O2 electrode system 显示文摘 | Yoon W S Grey C P Balasubramanian M | 2004 | Electrochemical and Solid-State Letters2004，7，： | 1 |
| 13 | Synthesis and characterization of nano-hydroxyapatite at ambient temperature using cationic surfactant显示文摘 | Shanthi P M S Ashok M Balasubramanian T | 2009 | Materials Letters2009，63，2425： | 1 |
| 14 | Wet deposition of trace metals in Singapore显示文摘 | Hu G P Balasubramanian R | 2003 | Water Air and Soil Pollution2003，144，14： | 1 |
| 15 | Knowledge scope:managing knowledge in context 显示文摘 | KWAN M M BALASUBRAMANIAN P | 2003 | Decision Support Sys-tems2003，35，46： | 1 |
| 16 | Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine 显示文摘 | CWIRLA SE BALASUBRAMANIAN P DUFFIN D J | 1997 | Science1997，276，5319： | 1 |
| 17 | Static analysis of circumferentially periodic structures with Potter’s scheme显示文摘 | RAMAMURTI V BALASUBRAMANIAN P | 1986 | Computers&Structures1986，22，3： | 1 |
| 18 | The implications of online investing显示文摘 | P Konana N M Menon S Balasubramanian | 2000 | Communications of the ACM2000，，1： | 1 |
| 19 | Recycling of Cattle Dung,Biogas Plant-Effluent and Water Hyacinth in Vermicultre显示文摘 | Balasubramanian P R Kasturi Bai R | 1995 | Bioresource Technology1995，52，： | 1 |
| 20 | Freevibration analysis of cyclic symmetric structures显示文摘 | BALASUBRAMANIAN P RAMAMURTI V | 1991 | Comm in Appl Num Meth1991，7，1： | 1 |
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