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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Coupled field finite element analysis of railway block brakes显示文摘 | BABU AS PRASADNS | 2009 | Proc Inst Mech Engineer Part F:J Rail & Rapid Transit2009，223，4： | 1 |
| 3 | Rehabilitating role of glutathione ester on cisplatin induced nephrotoxicity显示文摘 | Babu E Ebrahim AS Chandramohan N | 1999 | Ren Fail1999，21，2： | 1 |
| 4 | Kinetics of biosurfac- tant production by Pseudomonas aeruginosa strain BS2 from industrial wastes显示文摘 | Babu PS Vaidya AN Bal AS | 1996 | Biotechnol Lett1996，18，3： | 1 |
| 5 | Protocol guide phase-1 cardiac rehabilitation in patients with 'ST-elevation myocardial infarction in a rural hospital显示文摘 | Babu AS Noone MS Haneef M | 2010 | Heart Views2010，11，2： | 1 |
| 6 | Effects of early in- patient cardiac rehabilitation and Structured Home-based Program on Function among Patients with Congestive Heart Failure: A Randomized Controlled Trial显示文摘 | Babu AS Maiya AG George MM | 2011 | Heart Views2011，12，3： | 1 |
| 7 | The antioxidant and antiproliferative activities of methanolic extracts from Njavara rice bran 显示文摘 | Rao AS Reddy SG Babu PP | 2010 | BMC Complement Altern Med2010，10，： | 1 |
| 8 | Effect of exercise training on functional capacity & quality of life in head & neck cancer patients receiving chemoradiotherapy 显示文摘 | Samuel SR Maiya GA Babu AS | 2013 | Indian J Med Res2013，137，3： | 1 |
| 9 | Primary melanoma of the adrenal gland: a ease report 显示文摘 | Sasidharan K Babu AS Pandley AP | 1977 | J Urol1977，117，5： | 1 |
| 10 | Painful swollen leg-think beyond deep vein thrombosis or Baker's cyst 显示文摘 | Arumilli BR Lenin Babu V Paul AS | 2008 | World J Surg Oncol2008，18，6： | 1 |
| 11 | Benefits of exercise based cardiac rehab in congestive heart failure:A case se- ries 显示文摘 | Babu AS Maiya AG George MM | 2011 | Indian Heart J2011，63，5： | 1 |
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