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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Prophylactic nasogastric tube decompression: is its use justified? 显示文摘 | Schwartz CI Heyman AS Rao AC | 1995 | South Med J1995，88，： | 1 |
| 3 | Regulation of c-fos is affected byelectromagnetic fields 显示文摘 | Rao S Henderson AS | 1996 | Journal of Cellular Biochemistry1996，63，3： | 1 |
| 4 | Severe obesity in children and adolescents:identification,associated health risks,and treat ment approaches:a scientific statement from the American HeartAssociation显示文摘 | Kelly AS Barlow SE Rao G | 2013 | Circulation2013，128，15： | 1 |
| 5 | Sulphurmustard induced DNA damage in mice after dermal and inhalationexposure显示文摘 | Lakshmana Rao PV Vijayaraghavan R Bhaskar AS | 1999 | Toxicology1999，139，12： | 1 |
| 6 | Activation of mitogen- activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells 显示文摘 | Rao GN Baas AS Glasgow WC | 1994 | J Biol Chem1994，269，32： | 1 |
| 7 | Hippocampal changes associ- ated with early-life adversit and vulnerability to depression显示文摘 | Rao U Chen LA Bidesi AS | 2010 | Biol Psychiatry2010，67，4： | 1 |
| 8 | Writ- 5a has tumor suppressor activity in thyroid carcinoma显示文摘 | Kremenevskaja N von Wasielewski R Rao AS | 2005 | Oncogene2005，24，： | 1 |
| 9 | Murine liver allograft transplantation:tolerance and donor cell chimerism显示文摘 | Qian S Demetris AJ Murase N Rao AS Fung JJ Starzl TE | 1994 | Hepatology1994，19，4： | 1 |
| 10 | Wnt-5a has tumor suppressor activity in thyroid carcinoma显示文摘 | Kremenevskaja N von Wasielewski R Rao AS | 2005 | Oncogene2005，24，13： | 1 |
| 11 | Analysis of organ physiology in transgenic mice显示文摘 | Rao S Verkman AS | | 0，，： | 1 |
| 12 | Outbreak of carbapenem-resistant enterobacteriaceae at a long-term acute care hospital:sustained reductions in transmission through active surveillance and targeted interventions显示文摘 | Chitnis AS Caruthers PS Rao AK | | 0，，： | 1 |
| 13 | Wnt/beta-cate- nin signaling mediates antineoplastic effects of imatinib mesylate (gleevec) ia anaplastic thyroid cancer显示文摘 | Rao AS Kremenevskaja N von Wasielewski R | 2006 | J Clin Endocrinol Metab2006，91，1： | 1 |
| 14 | Propagation of dendritic cell progenitors from normal mouse liver using granulocyte/ macrophage colony-stimulating factor and their maturational development in the presence of type-1 collagen 显示文摘 | Lu L Woo J Rao AS | 1994 | J Exp Med1994，179，6： | 1 |
| 15 | Pigmented villonodular synovi-is (giant-cell tumor of the tendon sheath and synovial membrane): a review of eighty- one cases显示文摘 | Rao AS Vigorita VJ | 1984 | J Bone Joint Surg Am1984，66，1： | 1 |
| 16 | IL28B genetic variants and gender are associated with spontaneous clearance of hepatitis C virus infection 显示文摘 | Rao HY Sun DG Jiang D Yang RF Guo F Wang JH Liu F Zhang HY Zhang HH Du SC Jin Q Qin H Lok AS Wei L | 2012 | J Viral Hepat2012，19，3： | 1 |
| 17 | Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells 显示文摘 | Woo J Lu L Rao AS | 1994 | Transplantation1994，58，4： | 1 |
| 18 | Laminar flow induction of antioxidant response element-mediated genes in endothelial cells:a novel anti-inflammatory mechanism显示文摘 | Chen XL Varner SE Rao AS | 2003 | J Biol Chem2003，278，2： | 1 |
| 19 | Primary bone tumours of the spine:a 42-year survey from the leeds regional bone tumour registry显示文摘 | Kelley SP Ashford RU Rao AS | | 0，，： | 1 |
| 20 | Hematolymphoid cell trafficking,microchimerism,and GVH reactions after liver,bone marrow,and heart transplantation显示文摘 | Demetris AJ Murase N Fujisaki S Fung JJ Rao AS Starzl TE | 1993 | Transplant Proc1993，25，6： | 1 |
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