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| 1 | Evidence and explanation for the involvement of the nucleus accumbens in pain processing显示文摘The nucleus accumbens(NAc)is a subcortical brain structure known primarily for its roles in pleasure,reward,and addiction.Despite less focus on the NAc in pain research,it also plays a large role in the mediation of pain and is effective as a source of analgesia.Evidence for this involvement lies in the NAc’s cortical connections,functions,pharmacology,and therapeutic targeting.The NAc projects to and receives information from notable pain structures,such as the prefrontal cortex,anterior cingulate cortex,periaqueductal gray,habenula,thalamus,etc.Additionally,the NAc and other pain-modulating structures share functions involving opioid regulation and motivational and emotional processing,which each work beyond simply the rewarding experience of pain offset.Pharmacologically speaking,the NAc responds heavily to painful stimuli,due to its high density ofμopioid receptors and the activation of several different neurotransmitter systems in the NAc,such as opioids,dopamine,calcitonin gene-related peptide,γ-aminobutyric acid,glutamate,and substance P,each of which have been shown to elicit analgesic effects.In both preclinical and clinical models,deep brain stimulation of the NAc has elicited successful analgesia.The multi-functional NAc is important in motivational behavior,and the motivation for avoiding pain is just as important to survival as the motivation for seeking pleasure.It is possible,then,that the NAc must be involved in both pleasure and pain in order to help determine the motivational salience of positive and negative events. | Haley N.Harris Yuan B.Peng | 2020 | Neural Regeneration Research2020,15,4: | 3 |
| 2 | Phased Array Feed Experiments and Galactic HI Observations显示文摘The Phased Array Feed(PAF)is considered as one of the next generation receivers for radio telescopes,which can significantly enlarge the instantaneous Field-of-View of large aperture single dish radio telescopes and enable more flexible observing configurations.Study efforts on PAF development for radio telescopes have been made for more than two decades and have become more and more applicable.We report the development of an ambient-temperature 19 element L-band PAF system and the experimental results including its far field beam pattern and system temperature measurement,which achieve the expectations.Implementing the aperture array beam-forming method,we demonstrate a wide-field Galactic HI observations in the radio camera mode.The results indicate that this system might be applicable for strong Galactic transient detections.This system could be directly equipped to large telescopes like the Five-hundred-meter Aperture Spherical radio Telescope(FAST)and FAST array in the future. | B.Liu H.W.Xi D.J.Ding Z.W.Wang S.H.Yu Y.Zhu L.Yu X.Zhang J.L.Li L.J.Liu Q.Su Y.Wu C.J.Jin B.Peng | 2023 | Research in Astronomy and Astrophysics2023,23,8: | 0 |
| 3 | Ultrastrong steel strengthened by multiple shearable nanostructures显示文摘Precipitation of multiple strong nanoprecipitates is crucial for the development of ultrahigh-strength structural materials with a strength of 2.5 GPa or above.Nevertheless,the ductility usually loses rapidly with strength due to limited dislocation mobility and high cracking tendency if coarse non-deformable precipitates are employed.Herein,we report a 2.5 GPa maraging steel strengthened by an ultrahigh den-sity of intermeshed shearable nanostructures consisting of Ni(Al,Fe)nanoprecipitates and Mo-rich(∼30 at.%)disordered clusters,both of which assume coherent interfaces.The fully coherent B2-Ni(Al,Fe)par-ticles precipitate in an extremely fast fashion,effectively accelerating local aggregation of low-diffusivity Mo atoms and promoting the formation of Mo-rich clusters surrounding them.This elemental partition was found to be further enhanced by Co addition via depleting both residual Al and Mo within the ma-trix,leading to the formation of copious yet fine intermeshed nanostructures.During plastic deformation,the interlocked nanostructures not only enhance local cutting stress by combining long-range elastic and short-range chemically ordering effects but also improve dislocation activity and resist shear-induced plastic instability.The multiple shearable nanostructures endow decent ductility(>6%)of the 2.5 GPa steel,suggesting a new paradigm for designing ultrastrong steels. | L.J.Wang S.H.Jiang B.Peng B.H.Bai X.C.Liu C.R.Li X.J.Liu X.Y.Yuan H.H.Zhu Y.Wu H.Wang X.B.Zhang Z.P.Lu | 2023 | Journal of Materials Science & Technology2023,,30: | 0 |
| 4 | INFLUENCES OF NEODYMIUM ON MAGNETIC CHARACTERISTICS OF ELECTROPLATING CoNdNiMnP FILMS显示文摘In order to improve the performances of electroplating permanent magnetic films, neodymium is introduced into the electroplating CoNiMnP permanent magnetic films. The influences of the neodymium content are also investigated by varying NdCl3 plating bath concentration. The neodymium-doped films are analyzed by energy dispersive spectrum (EDS), vibrating sample magnetometer (VSM) and magnetic force microscope (MFM). The experimental results show that high magnetic performances of CoNdNiMnP permanent magnetic films with vertical anisotropy could be fabricated with current density 5mA/cm2 at room temperature. With the increasing of neodymium contents, the magnetic properties of films were improved. However when neodymium contents exceeded 3.5wt%, the magnetic properties of films are not improved any more. The increase of film magnetic properties results from the ferromagnetic-coupling between light rare earth element-neodymium and transition metal element-cobalt. | H.C.Jiang W.L.Zhang J.P.Zhang W.X.Zhang B.Peng S.Q.Yang | 2005 | Acta Metallurgica Sinica(English Letters)2005,18,2: | 0 |
| 5 | THE INFLUENCES OF SOLUTION PH AND CURRENT DENSITY ON COERCIVITY OF ELECTROPLATING CoNdNiMnP PERMANENT MAGNETIC ALLOY FILM ARRAYS显示文摘The influences of plating bath solution PH and current density on coercivity of electroplating CoNdNiMnP permanent magnetic film arrays were studied. The experiment results show that both for solution PH and current density there were the best depositing parameters. Too high and too low plating bath solution PH or current density both result in decreasing of the film array coercivity. When solution PH is 3.5 and current density is 5mA/cm2, the prepared film array coercivity can reach the maximum. | H.C.Jiang W.L.Zhang J.P.Zhang W.X.Zhang B.Peng S.Q.Yang | 2004 | Acta Metallurgica Sinica(English Letters)2004,17,5: | 0 |