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| 1 | Neoadjuvant chemotherapy for locally advanced cervical cancer显示文摘Neoadjuvant chemotherapy followed by surgery(NCS) has not been fully evaluated clinically. Currently, the main regimen of neoadjuvant chemotherapy(NAC) used in NCS includes cisplatin. The antitumor effects of NAC reduce lymph node metastasis and the tumor diameter in patients prior to surgery, and this can reduce the number of high risk patients who require postoperative radiation therapy. Many randomized controlled trials(RCTs) have examined the long-term prognosis of NCS compared to primary surgery, but the utility of NCS remains uncertain. The advent of concurrent chemoradiotherapy(CCRT) has markedly improved the outcome of radiotherapy(RT), and CCRT is now used as a standard method in many cases of advanced bulky cervical cancer. NCS gives a better treatment outcome than radiation therapy alone, but it is important to verify that NCS gives a similar or better outcome compared to CCRT. | Takashi Iwata Azumi Miyauchi Yukako Suga Hiroshi Nishio Masaru Nakamura Akiko Ohno Nobumaru Hirao Tohru Morisada Kyoko Tanaka Hiroki Ueyama Hidemichi Watari Daisuke Aoki | 2016 | Chinese Journal of Cancer Research2016，28，2： | 20 |
| 2 | 不同工作介质下二氧化锰/膨胀石墨复合材料的电化学电容器行为显示文摘研究了氧化还原法制备二氧化锰/膨胀石墨复合材料用作电化学电容器,利用热重分析、比表面及X射线衍射方法对材料的组成及结构进行了表征,利用三电极循环伏安及充放电循环法研究了材料在硫酸钠、氯化钠、氯化钾及硝酸钾不同电解质中的电化学行为.研究结果表明,二氧化锰以非晶态的形式在复合材料中存在,膨胀石墨起良好电导作用,随其用量的增加,复合材料的比表面下降,但二氧化锰的比电容增加.不同工作介质中电化学行为显示,复合材料电化学行为的不同主要跟阳离子的种类有关.在钠离子电解质中,复合材料电极体现较高的表观电容和真实电容,在钾盐电解质体系中,复合材料电极的电流响应速度比较快,这是由于钠盐和钾盐溶液具有不同的水合数、水合半径和电导率.当复合材料中膨胀石墨的用量为24%左右时,复合材料在2mV/s扫描速度下,在1mol/LNa2SO4溶液中体现的比电容为220F/g,复合材料显示优良的循环性能. | 万传云 AZUMI Kazuhisa KONNO Hidetaka | 2007 | 化学学报2007，65，17： | 7 |
| 3 | Successful laparoscopic splenectomy after living-donor liver transplantation for thrombocytopenia caused by antiviral therapy显示文摘Although interferon (IFN) based therapy for recurrent hepatitis C virus (HCV) infection after liver transplantation has been widely accepted, it induces various adverse effects such as thrombocytopenia, resulting in its interruption. Recently, concomitant splenectomy at the time of living donor liver transplantation (LDLT) has been tried to overcome this problem, but this procedure leads to several complications such as excessive intraoperative bleeding and serious infection. A 60-year-old female received LDLT using a left lobe graft from her second son for liver failure caused by hepatitis C-related cirrhosis. Six months after LDLT, she was diagnosed as recurrent HCV infection by liver biopsy. IFN monotherapy was started from 7 mo after LDLT and her platelet count decreased to less than 50 000/μL, which thus made it necessary to discontinue the treatment. We decided to attempt laparoscopic splenectomy (LS) under general anesthesia. Since intra-abdominal findings did not show any adhesion formations around the spleen, LS could be successfully performed. After LS, since her platelet count immediately increased to 225 000/μL 14 d after operation, IFN therapy was restarted and we could convert the combination therapy of IFN and ribavirin, resulting in no detectable viral marker. Inconclusion, LS can be performed safely even after LDLT, and LS after LDLT is a feasible and less invasive modality for thrombocytopenia caused by antiviral therapy. | Hiroyuki Kato Masanobu Usui Yoshinori Azumi Ichiro Ohsawa Masashi Kishiwada Hiroyuki Sakurai Masami Tabata Shuji Isaji | 2008 | World Journal of Gastroenterology2008，14，26： | 7 |
| 4 | Clinical significance of different periampullary diverticulum classifications for endoscopic retrograde cholangiopancreatography cannulation显示文摘BACKGROUND Different types of periampullary diverticulum(PAD) may differentially affect the success of endoscopic retrograde cholangiopancreatography(ERCP) cannulation,but the clinical significance of the two current PAD classifications for cannulation is limited.AIM To verify the clinical value of our newly proposed PAD classification.METHODS A new PAD classification(Li-Tanaka classification) was proposed at our center.All PAD patients with native papillae who underwent ERCP from January 2012 to December 2017 were classified according to three classification systems, and the effects of various types of PAD on ERCP cannulation were compared.RESULTS A total of 3564 patients with native papillae were enrolled, including 967(27.13%)PAD patients and 2597(72.87%) non-PAD patients. In the Li-Tanaka classification, type Ⅰ PAD patients exhibited the highest difficult cannulation rate(23.1%, P = 0.01), and type Ⅱ and Ⅳ patients had the highest cannulation success rates(99.4% in type Ⅱ and 99.3% in type Ⅳ, P < 0.001). In a multivariableadjusted logistic model, the overall successful cannulation rate in PAD patients was higher than that in non-PAD patients [odds ratio(OR) = 1.87, 95% confidence interval(CI): 1.04-3037, P = 0.037]. In addition, compared to the non-PAD group,the difficulty of cannulation in the type Ⅰ PAD group according to the Li-Tanaka classification was greater(OR = 2.04, 95%CI: 1.13-3.68, P = 0.004), and the successful cannulation rate was lower(OR = 0.27, 95%CI: 0.11-0.66, P < 0.001),while it was higher in the type Ⅱ PAD group(OR = 4.44, 95%CI: 1.61-12.29, P <0.01).CONCLUSION Among the three PAD classifications, the Li-Tanaka classification has an obvious clinical advantage for ERCP cannulation, and it is helpful for evaluating potentially difficult and successful cannulation cases among different types of PAD patients. | Ping Yue Ke-Xiang Zhu Hai-Ping Wang Wen-Bo Meng Jian-Kang Liu Lei Zhang Xiao-Liang Zhu Hui Zhang Long Miao Zheng-Feng Wang Wen-Ce Zhou Azumi Suzuki Kiyohito Tanaka Xun Li | 2020 | World Journal of Gastroenterology2020，26，19： | 5 |
| 5 | A standardized technique for safe pancreaticojejunostomy:Pair-Watch suturing technique显示文摘AIM:To prevent pancreatic leakage after pancreaticoje-junostomy,we designed a new standardized technique that we term the 'Pair-Watch suturing technique'.METHODS:Before anastomosis,we imagine the faces of a pair of watches on the jejunal hole and pancreatic duct.The first stitch was put between 9 o'clock of the pancreatic side and 3 o'clock of the jejunal side,and a total of 7 stitches were put on the posterior wall,followed by the 5 stitches on the anterior wall.Using this technique,twelve stitches can be sutured on the first layer anastomosis regardless of the caliber of the pancreatic duct.In all cases the amylase activity of the drain were measured.A postoperative pancreatic fistula was diagnosed using postoperative pancreatic fistula grading.RESULTS:From March 2007 to July 2008,29 consecutive cases underwent pancreaticojejunostomy using this technique.Pathologic examination results showed pancreatic carcinoma(n=14),intraductal papillary-mucinous neoplasm(n=10),intraductal papillary-mucinous carcinoma(n=1),carcinoma of ampulla of Vater(n=1),carcinoma of extrahepatic bile duct(n=1),metastasis of renal cell carcinoma(n=1),and duodenal carcinoma(n=1).Pancreaticojejunal anastomoses using this technique were all watertight during the surgical procedure.The mean diameter of main pancreatic duct was 3.4 mm(range 2-7 mm).Three patients were recognized as having an amylase level greater than 3 times the serum amylase level,but all of them were diagnosed as grade A postoperative pancreatic fistula grading and required no treatment.None of the cases developed complications such as hemorrhage,abdominal abscess,and pulmonary infection.There was no postoperative mortality.CONCLUSION:Our technique is less complicated than other methods and very secure,providing reliable anastomosis for any size of pancreatic duct. | Yoshinori Azumi Shuji Isaji Hiroyuki Kato Yuu Nobuoka Naohisa Kuriyama Masashi Kishiwada Takashi Hamada Shugo Mizuno Masanobu Usui Hiroyuki Sakurai Masami Tabata | 2010 | World Journal of Gastrointestinal Surgery2010，2，8： | 2 |
| 6 | Esophageal epithelial surface in patients with gastroesophageal reflux disease:An electron microscopic study显示文摘AIM: To investigate the intercellular spaces between the most superficially located esophageal epithelial cells in patients with gastroesophageal reflux disease (GERD). METHODS: Eighteen patients with erosive esophagitis, 10 patients with non-erosive reflux disease (NERD), and 18 normal asymptomatic volunteers were enrolled. Biopsy specimens were obtained from the lower esophageal mucosa without ulcer or erosion. Scanning electron microscopy was employed to investigate the tightness of the superficial cellular attachment. RESULTS: The intercellular space between the most superficially located epithelial cells in patients with erosive esophagitis or NERD was not different from that in asymptomatic healthy individuals. CONCLUSION: Widened luminal intercellular spaces of esophageal superficial epithelium are not responsible for the induction of reflux symptoms in patients with GERD. | Takane Azumi Kyoichi Adachi Kenji Furuta Shuji Nakata Shunji Ohara Kenji Koshino Masaharu Miki Terumi Morita Takashi Tanimura Nobuo Ashizawa Yoshikazu Kinoshita | 2008 | World Journal of Gastroenterology2008，14，37： | 2 |
| 7 | Liver Transplantation in the Management of Hepatic Epithelioid Hemangioendothelioma: A Single-Center Experience and Review of the Literature显示文摘 | N. Agrawal S. Parajuli P. Zhao R. Satoskar J. Laurin N. Azumi C. Matsumoto K. Shetty | 2011 | Transplantation Proceedings2011，，7： | 2 |
| 8 | Choledocholithiasis characteristics with periampullary diverticulum and endoscopic retrograde cholangiopancreatography procedures:Comparison between two centers from Lanzhou and Kyoto显示文摘BACKGROUND Most of study regarding periampullary diverticulum(PAD)impact on endoscopic retrograde cholangiopancreatography(ERCP)therapy for choledocholithiasis based on data from one endoscopy center and lacked to compare the clinical characteristic of choledocholithiasis with PAD from different geographical patients.AIM To compare the choledocholithiasis clinical characteristics between two regional endoscopy centers and analyze impacts of clinical characteristics on ERCP methods for choledocholithiasis patients with PAD.METHODS Patients seen in two endoscopy centers(The First Hospital of Lanzhou University,Lanzhou,Gansu Province,China,and Kyoto Second Red Cross Hospital,Kyoto,Japan)underwent ERCP treatment for the first time between January 2012 and December 2017.The characteristics of choledocholithiasis with PAD were compared between the two centers,and their ERCP procedures and therapeutic outcomes were analyzed.RESULTS A total of 829 out of 3608 patients in the Lanzhou center and 241 out of 1198 in the Kyoto center had choledocholithiasis with PAD.Lots of clinical characteristics were significantly different between the two centers.The common bile duct(CBD)diameter was wider,choledocholithiasis size was lager and multiple CBD stones were more in the Lanzhou center patients than those in the Kyoto center patients(14.8±5.2 mm vs 11.6±4.2 mm,12.2±6.5 mm vs 8.2±5.3 mm,45.3%vs 20.3%,P<0.001 for all).In addition,concomitant diseases,such as acute cholangitis,gallbladder stones,obstructive jaundice,cholecystectomy,and acute pancreatitis,were significantly different between the two centers(P=0.03 to<0.001).In the Lanzhou center,CBD diameter and choledocholithiasis size were lower,and multiple CBD stones and acute cholangitis were less in non-PAD patients than those in PAD patients(13.4±5.1 mm vs 14.8±5.2 mm,10.3±5.4 mm vs 12.2±6.5,39%vs 45.3%,13.9%vs 18.5%,P=0.002 to<0.001).But all these characteristics were not significantly different in the Kyoto center.The proportions of endoscopic sphincterotomy(EST),endoscopic balloon dilatation(EPBD),and EST+EPBD were 50.5%,1.7%,and 42.5%in the Lanzhou center and 90.0%,0.0%,and 0.4%in the Kyoto center,respectively.However,the overall post-ERCP complication rate was not significantly different between the two centers(8.9%in the Lanzhou and 5.8%in the Kyoto.P=0.12).In the Lanzhou center,the difficulty rate in removing CBD stones in PAD was higher than in non-PAD group(35.3%vs 26.0%,P<0.001).But the rate was no significant difference between the two groups in Kyoto center.The residual rates of choledocholithiasis were not significantly different between the two groups in both centers.Post-ERCP complications occurred in 8.9%of the PAD patients and 8.1%of the non-PAD patients in the Lanzhou Center,and it occurred in 5.8%in PAD patients and 10.0%in non-PAD patients in the Kyoto center,all P>0.05.CONCLUSION Many clinical characteristics of choledocholithiasis patients with PAD were significantly different between the Lanzhou and Kyoto centers.The patients had larger and multiple stones,wider CBD diameter,and more possibility of acute cholangitis and obstructive jaundice in the Lanzhou center than those in the Kyoto center.The ERCP procedures to manage native duodenal papilla were different depending on the different clinical characteristics while the overall post-ERCP complications were not significantly different between the two centers.The stone residual rate and post-ERCP complications were not significantly different between choledocholithiasis patients with PAD and without PAD in each center. | Ke-Xiang Zhu Ping Yue Hai-Ping Wang Wen-Bo Meng Jian-Kang Liu Lei Zhang Xiao-Liang Zhu Hui Zhang Long Miao Zheng-Feng Wang Wen-Ce Zhou Azumi Suzuki Kiyohito Tanaka Xun Li | 2022 | World Journal of Gastrointestinal Surgery2022，14，2： | 2 |
| 9 | Immunohistochemical localization of endothelial cell derived lipase in atherosclerotic human coronary arteries 显示文摘 | Azumi H Hirata K lshida T | 2003 | Cardiovasc Res2003，58，3： | 1 |
| 10 | Halocyamines:novel antimicrobial tetrapeptide-like substances isolated from the hemocytes of the solitary ascidian,Halocynthia roretzi显示文摘 | Azumi K Yokosawa H Ishii S | 1990 | Biochemistry1990，29，1： | 1 |
| 11 | Halocyamines:novel antimicrobial tetrapeptide-like substances isolated from the hemocytes of the solitary ascidian Halocynthia roretzi显示文摘 | Azumi K Yokosawa H Ishii S | 1990 | Biochemistry1990，29，1： | 1 |
| 12 | Stromal invasion by carcinoma of the cervix: assessment with dynamic imaging显示文摘 | Seki H Azumi R | 1997 | AJR1997，168，6： | 1 |
| 13 | Magnetic minerals and magnetic properties of the Siwalik Group sediments of the Karnali River section in Nepal 显示文摘 | Pitambar G Azumi H Raj RK | 2000 | Earth Planets and Space2000，52，5： | 1 |
| 14 | Confirmation of heat generation and anomalous element caused by plasma electrolysis in the liquid显示文摘 | Mizuno T Ohmori T Azumi K | 2000 | Conference Proceedings2000，70，： | 1 |
| 15 | Direct plating of electroless Ni-P layers on sputter-deposited Al-Ni alloy films 显示文摘 | AZUMI K YUGIRI T KURIHARA T | 2003 | Journal of the Electrochemical Society2003，150，7： | 1 |
| 16 | A novel inhibitor of bacterial endotoxin derived from cinnamon bark显示文摘 | Azumi S Tanimura A Tanamoto K | 1997 | Biochemical and Bio-physical Research Communications1997，234，： | 1 |
| 17 | Stented pancreaticojejunostomy ( with video) 显示文摘 | Azumi Y Isaji S | 2012 | JHepatobiliary Pancreat Sci2012，19，2： | 1 |
| 18 | Liquid crystalline behavior of α-substituted oligothiophenes 显示文摘 | Yamada T Azumi R Tachibana H | 2001 | Chem Lett2001，1022，： | 1 |
| 19 | Optimization of pulsed electrodeposition of aluminum from AlCl 3 -1-ethyl-3-methylimidazolium chloride ionic liquid显示文摘 | Jinwei Tang Kazuhisa Azumi | 2010 | Electrochimica Acta2010，，3： | 1 |
| 20 | Spectroscopic photoresponse of the passive film formed on iron显示文摘 | Ohtsuka T Sato N | 1986 | J Electrochem Soc1986，133，7： | 1 |
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