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| 1 | 胃癌预防亚太地区共识指南显示文摘背景与目的:胃癌是亚太地区的主要健康负担之一,但对其预防策略尚缺乏共识。本共识会议旨在评价预防胃癌的策略。方法:多学科专家组应用德尔菲(Delphi)法制订共识条文,提呈相关数据,对证据等级、推荐强度以及共识水平予以分级。结果:幽门螺杆菌(H.pylori)感染是非贲门胃腺癌必要但非充分的致病因子。盐的高摄入与胃癌强烈相关。新鲜果蔬对胃癌具有预防作用,但维生素和其他饮食补充并不能预防胃癌。H.pylori感染中的宿主-细菌相互作用导致不同类型的胃炎和胃酸分泌,从而决定疾病结局。胃癌阳性家族史是一个重要的危险因素。低血清胃蛋白酶原反映胃萎缩程度,可作为检出胃癌高危人群的标志物。H.pylori筛查和治疗被推荐作为减少高危人群胃癌危险性的一种策略,该策略在萎缩性胃炎发生前实施最为有效,但并不排除对胃癌高危人群的内镜监测。对胃癌低危人群不推荐行H.pylori筛查。H.pylori感染的一线治疗应遵循国家治疗指南。结论:高危人群中H.pylori筛查和根除策略可能会减少胃癌的发生率,本共识根据现有证据予以推荐。 | Kwong Ming Fock Nick Talley Paul Moayyedi Richard Hunt Takeshi Azuma Kentaro Sugano Shu Dong Xiao Shiu Kum Lam Khean Lee Goh Tsutomu Chiba Naomi Uemura Jae G Kim Nayoung Kim Tiing Leong Ang Varocha Mahachai Hazel Mitchell Abdul Aziz Rani Jyh Ming Liou Ratha-korn Vilaichone Jose Sollanor 钱本余 | 2008 | 胃肠病学2008，13，4： | 37 |
| 2 | 大环内酯类抗生素25年应用总结--面向常见病的应用进展显示文摘 | Arata Azuma 安云霞(翻译) 张放(审校) 康健(审校) | 2009 | 中国实用内科杂志2009，29，10： | 11 |
| 3 | DOG1 is useful for diagnosis of KIT-negative gastrointestinal stromal tumor of stomach显示文摘Approximately 80%-95%of gastrointestinal stromal tumors(GISTs)show positive staining for KIT,while the other 5%-20%show negative staining.If the tumor is negative for KIT,but is positive for CD34,a histological diagnosis is possible.However,if the tumor is negative for KIT,CD34,S-100,and SMA,a definitive diagnosis is often challenging.Recently,Discovered on GIST-1(DOG1)has received considerable attention as a useful molecule for the diagnosis of GIST.DOG1,a membrane channel protein,is known to be overexpressed in GIST.Because the sensitivity and specificity of DOG1 are higher than those of KIT,positive staining for DOG1has been reported,even in KIT-negative GISTs.KITnegative GISTs most commonly arise in the stomach and are mainly characterized by epithelioid features histologically.We describe our experience with a rare case of a KIT-negative GIST of the stomach that was diagnosed by positive immunohistochemical staining for DOG1 in a patient who presented with severe anemia.Our findings suggest that immunohistochemical staining for DOG1,in addition to gene analysis,is useful for the diagnosis of KIT-negative tumors that are suspected to be GISTs. | Takuya Wada Satoshi Tanabe Kenji Ishido Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Akira Naruke Myunguchul Kim Wasaburo Koizumi Tetsuo Mikami | 2013 | World Journal of Gastroenterology2013，19，47： | 11 |
| 4 | A New Titanosauriform Sauropod from the Early Late Cretaceous of Dongyang,Zhejiang Province显示文摘摘要:一张新 titanosauriform sauropod Dongyangosaurus sinensis 情报。et sp。nov。从 Dongyang 县的早迟了的白垩纪,浙江省,基于一架部分 postcranial 骨骼被树立。它被复杂薄片在神经脊骨的侧面的表面和背面的 vertebrae 的 postzygapophyses 上描绘,背面的 vertebrae 的 prezygapophyses 的腹的表面上的一个不同的窝,不同 fossae 也是前面的尾的 vertebrae 的 postzygapophysis 的侧面的表面上的现在;耻骨比坐骨短,耻骨的小闭塞物孔伸长了,并且将近关门了。在 Dongyangosaurus 的背面的 vertebrae 的薄板复杂性显示 titanosauriformes 的更高的差异在中国发生在早迟了的白垩纪期间。 | LU Junchang Yoichi AZUMA CHEN Rongjun ZHENG Wenjie JIN Xingsheng | 2008 | Acta Geologica Sinica(English Edition)2008，82，2： | 10 |
| 5 | Interferon alpha plus ribavirin combination treatment of Japanese chronic hepatitis C patients with HCV genotype 2:A project of the Kyushu University Liver Disease Study Group显示文摘瞄准:决定一座干扰素高山的功效哈并且为感染遗传型 2 的丙肝病毒(HCV ) 的日本病人的 ribavirin 联合治疗,多中心研究回顾地被分析。方法:总共,有 HCV 遗传型 2 的 173 个病人每天一个星期和 ribavirin 的 600-800 mg 为 24 wk 三次皮下地收到 interferon-alpha。结果:总的来说持续的 virological 反应(SVR ) ,在浆液的定义同样无法发现的 HCV RNA,在治疗的结束以后的 24 wk,在 84.4% 显著地高,(146/173 ) 由 intention-to-treat 分析。在 SVR 的有效差量有或没有 ribavirin (46.9% 对 92.9%) 的中止在病人之间被发现,但是没有差别有或没有 ribavirin 的剂量减小在那些之间被发现。在 SVR 的有效差量也与 16 或更与不到 16 wk 和病人在病人之间被发现 ribavirin 治疗(34.8% 对 92.0%) 的星期。结论:24-wk 干扰素和 ribavirin 治疗为有 HCV 遗传型 2 的日本病人是高度有效的。SVR 的重要预言者是 ribavirin 治疗的继续多达 16 个星期。 | Norihiro Furusyo Masaki Katoh Yuichi Tanabe Eiji Kajiwara Toshihiro Maruyama Junya Shimono Hironori Sakai Makoto Nakamuta Hideyuki Nomura Akihide Masumoto Shinji Shimoda Kazuhiro Takahashi Koichi Azuma Jun Hayashi Kyushu University Liver Disease Study Group | 2006 | World Journal of Gastroenterology2006，12，5： | 8 |
| 6 | Initiation of plate tectonics in the Hadean: Eclogitization triggered by the ABEL Bombardment显示文摘When plate tectonics began on the Earth has been long debated and here we argue this topic based on the records of Earth-Moon geology and asteroid belt to conclude that the onset of plate tectonics was during the middle Hadean(4.37-4.20 Ga). The trigger of the initiation of plate tectonics is the ABEL Bombardment, which delivered oceanic and atmospheric components on a completely dry reductive Earth, originally comprised of enstatite chondrite-like materials. Through the accretion of volatiles, shock metamorphism processed with vaporization of both CI chondrite and supracrustal rocks at the bombarded location, and significant recrystallization went through under wet conditions, caused considerable eclogitization in the primordial continents composed of felsic upper crust of 21 km thick anorthosite, and 50 km or even thicker KREEP lower crust. Eclogitization must have yielded a powerful slab-pull force to initiate plate tectonics in the middle Hadean. Another important factor is the size of the bombardment. By creating Pacific Ocean class crater by 1000 km across impactor, rigid plate operating stagnant lid tectonics since the early Hadean was severely destroyed, and oceanic lithosphere was generated to have bi-modal lithosphere on the Earth to enable the operation of plate tectonics.Considering the importance of the ABEL Bombardment event which initiated plate tectonics including the appearance of ocean and atmosphere, we propose that the Hadean Eon can be subdivided into three periods:(1) early Hadean(4.57-4.37 Ga),(2) middle Hadean(4.37-4.20 Ga), and(3) late Hadean(4.20-4.00 Ga). | Shigenori Maruyama M.Santosh Shintaro Azuma | 2018 | Geoscience Frontiers2018，9，4： | 8 |
| 7 | Variations and mutations in the hepatitis B virus genome and their associations with clinical characteristics显示文摘Hepatitis B virus(HBV) infection is major global issue, because chronic HBV infection is strongly associated with liver cancer. HBV spread worldwide with variousmutations and variations. This variability, called quasispecies, is derived from no proof-reading capacity of viral reverse transcriptase. So far, thousands of studies reported that the variety of genome is closely related to the geographic distribution and clinical characteristics. Recent technological advances including capillary sequencer and next generation sequencer have made in easier to analyze mutations. The variety of HBV genome is related to not only antigenicity of HBs-antigen but also resistance to antiviral therapies. Understanding of these variations is important for the development of diagnostic tools and the appropriate therapy for chronic hepatitis B. In this review, recent publications in relation to HBV mutations and variations are updated and summarized. | Yoshihiko Yano Takeshi Azuma Yoshitake Hayashi | 2015 | World Journal of Hepatology2015，7，3： | 8 |
| 8 | New Nodosaurid Dinosaur from the Late Cretaceous of Lishui, Zhejiang Province, China显示文摘nodosaurid 恐龙的一个新类和种:Zhejiangosaurus lishuiensisgen。et sp。nov。此处被树立。它被由至少三真骶的 vertebrae,熔化形成 presacral 杆的 5 尾的背面的 vertebrae,从身体的中间的线的肠骨的长苗条的 preacetabular 过程的宽分叉,和定位在的 fourthtrochanter 组成的骶骨描绘大腿骨中间长度。 | LU Junchang JIN Xingsheng SHENG Yiming LI Yihong WANG Guoping Yoichi AZUMA | 2007 | Acta Geologica Sinica(English Edition)2007，81，3： | 8 |
| 9 | Predominant mucosal IL-8 mRNA expression in non-cagA Thais is risk for gastric cancer显示文摘AIM:To study gastric mucosal interleukine-8(IL-8) mRNA expression,the cytotoxin-associated gene A(cagA) mutation,and serum pepsinogen(PG)Ⅰ/Ⅱ ratio related risk in Thai gastric cancer.METHODS:There were consent 134 Thai non-cancer volunteers who underwent endoscopic narrow band imaging examination,and 86 Thais advance gastric cancer patients who underwent endoscopic mucosal biopsies and gastric surgery.Tissue samples were taken by endoscopy with 3 points biopsies.The serum PG Ⅰ,Ⅱ,and Helicobacter pylori(H.pylori) immunoglobulin G(IgG) antibody for H.pylori were tested by enzyme-linked immunosorbent assay technique.The histopathology description of gastric cancer and non-cancer with H.pylori detection was defined with modified Sydney Score System.Gastric mucosal tissue H.pylori DNA was extracted and genotyped for cagA mutation.Tissue IL-8 and cyclooxygenase-2(COX-2) mRNA expression were conducted by real time relative quantitation polymerase chain reaction.From 17 Japanese advance gastric cancer and 12 benign gastric tissue samples,all were tested for genetic expression with same methods as well as Thai gastric mucosal tissue samples.The multivariate analysis was used for the risk study.Correlation and standardized t-test were done for quantitative data,P value < 0.05 was considered as a statistically significant.RESULTS:There is a high non cagA gene of 86.8 per cent in Thai gastric cancer although there are high yields of the East Asian type in the positive cagA.The H.pylori infection prevalence in this study is reported by combined histopathology and H.pylori IgG antibody test with 77.1% and 97.4% of sensitivity and specificity,respectively.The serum PG Ⅰ/Ⅱ ratio in gastric cancer is significantly lower than in the non-cancer group,P = 0.045.The serum PG Ⅰ/Ⅱ ratio of less than 3.0 and IL-8 mRNA expression ≥ 100 or log 10 ≥ 2 are significant cut off risk differences between Thai cancer and non-cancer,P = 0.03 and P < 0.001,respectively.There is a significantly lower PGI/II ratio in Japanese than that in Thai gastric cancer,P = 0.026.Serum PG Ⅰ/Ⅱ ratio at cut off less than 3.0 and IL-8 mRNA expression Raw RQ > 100 or log 10 > 2 are significantly difference between Thai cancer group when compared to non-cancer group,P = 0.013 and P < 0.001,respectively.In the correlation study,low PG Ⅰ/Ⅱ ratio does not associate with chronic atrophic gastritis severity score in Thais non-cancer cases.However,there is a trend,but not significant convert correlation between IL-8 mRNA expression level and low PG Ⅰ/Ⅱ ratio in Thai positive H.pylori infection.The high expression of IL-8 gene demonstrates a poorer prognosis by stage and histology.CONCLUSION:Predominant gastric mucosal IL-8 mRNA expression level,H.pylori infection,and low PG Ⅰ/Ⅱ ratio are relative risks for Thai gastric cancer without correlation with cagA mutation. | Sirikan Yamada Shunji Kato Takeshi Matsuhisa Luksana Makonkawkeyoon Masaru Yoshida Thiraphat Chakrabandhu Nirush Lertprasertsuk Pawit Suttharat Bandhuphat Chakrabandhu Shin Nishiumi Wilaiwan Chongraksut Takeshi Azuma | 2013 | World Journal of Gastroenterology2013，19，19： | 8 |
| 10 | Magnifying endoscopy in upper gastroenterology for assessing lesions before completing endoscopic removal显示文摘Any prognosis of gastrointestinal (GI) cancer is closely related to the stage of the disease at diagnosis.Endoscopic submucosal dissection (ESD) and en bloc endoscopic mucosal resection (EMR) have been performed as curative treatments for many early-stage GI lesions in recent years.The technologies have been widely accepted in many Asian countries because they are minimally invasive and supply thorough histopathologic evaluation of the specimens.However,before engaging in endoscopic therapy,an accurate diagnosis is a precondition to effecting the complete cure of the underlying malignancy or carcinoma in situ.For the past few years,many new types of endoscopic techniques,including magnifying endoscopy with narrow-band imaging (MENBI),have emerged in many countries because these methods provide a strong indication of early lesions and are very useful in determining treatment options before ESD or EMR.However,to date,there is no comparable classification equivalent to 'Kudo's Pit Pattern Classification in the colon',for the upper GI,there is still no clear internationally accepted classification system of magnifying endoscopy.Therefore,in order to help unify some viewpoints,here we will review the defining optical imaging characteristics and the current representative classifications of microvascular and microsurface patterns in the upper GI tract under ME-NBI,describe the accurate relationship between them and the pathological diagnosis,and their clinical applications prior to ESD or en bloc EMR.We will also discuss assessing the differentiation and depth of invasion,defying the lateral spread of involvement and targeting biopsy in real time. | Ning-Li Chai En-Qiang Ling-Hu Yoshinori Morita Daisuke Obata Takashi Toyonaqa Takeshi Azuma Ben-Yan Wu | 2012 | World Journal of Gastroenterology2012，18，12： | 7 |
| 11 | Feasibility and safety of endoscopic submucosal dissection for lower rectal tumors with hemorrhoids显示文摘AIM: To evaluate the feasibility and safety of endoscopic submucosal dissection(ESD) for lower rectal lesions with hemorrhoids.METHODS: The outcome of ESD for 23 lesions with hemorrhoids(hemorrhoid group) was compared with that of 48 lesions without hemorrhoids extending to the dentate line(non-hemorrhoid group) during the same study period. RESULTS: Median operation times(ranges) in the hemorrhoid and non-hemorrhoid groups were 121(51-390) and 130(28-540) min. The en bloc resection rate and the curative resection rate in the hemorrhoid group were 96% and 83%, and they were 100% and 90% in the non-hemorrhoid group, respectively. In terms of adverse events, perforation and postoperative bleeding did not occur in both groups. In terms of the clinical course of hemorrhoids after ESD, the rate of complete recovery of hemorrhoids after ESD in lesions with resection of more than 90% was significantly higher than that in lesions with resection of less than 90%.CONCLUSION: ESD on lower rectal lesions with hemorrhoids could be performed safely, similarly to that on rectal lesions extending to the dentate line without hemorrhoids. In addition, all hemorrhoids after ESD improved to various degrees, depending on the resection range. | Shinwa Tanaka Takashi Toyonaga Yoshinori Morita Namiko Hoshi Tsukasa Ishida Yoshiko Ohara Tetsuya Yoshizaki Fumiaki Kawara Eiji Umegaki Takeshi Azuma | 2016 | World Journal of Gastroenterology2016，22，27： | 6 |
| 12 | Pulmonary embolism after arterial chemoembolization for hepatocellular carcinoma: An autopsy case report显示文摘We report an extremely rare case of pulmonary lipiodol embolism with acute respiratory distress syndrome(ARDS) after transcatheter arterial chemoembolization(TACE) for hepatocellular carcinoma(HCC). A 77-yearold man who was diagnosed with a huge HCC wasadmitted for TACE. Immediately after the procedure, this patient experienced severe dyspnea. We suspected that his symptoms were associated with a pulmonary lipiodol embolism after TACE, and we began intensive treatment. However, his condition did not improve, and he died on the following day. A subsequent autopsy revealed that the cause of death was ARDS due to pulmonary lipiodol embolism. No cases have been previously reported for which an autopsy was performed to explain the most probable mechanism of pulmonary lipiodol embolism; thus, ours is the first report for such a rare case. | Keiichi Hatamaru Shunjiro Azuma Takuji Akamatsu Takeshi Seta Shunji Urai Yoshito Uenoyama Yukitaka Yamashita Kazuo Ono | 2015 | World Journal of Gastroenterology2015，21，4： | 5 |
| 13 | Hypoxia-inducible factor 1 alpha and vascular endothelial growth factor overexpression in ischemic colitis显示文摘AIM: To examine the etiology and pathophysiology in human ischemic colitis from the viewpoint of ischemic favors such as hypoxia-inducible factor 1 alpha (HIF-1alpha and vascular endothelial growth factor (VEGF).METHODS: Thirteen patients with ischemic colitis and 21 normal controls underwent colonoscopy. The follow-up colonoscopy was performed in 8 patients at 7 to 10 d after theoccurrence of ischemic colitis. Biopsy samples were subjected to real-time RT-PCR and immunohistochemistry to detect the expression of HIF-1 alpha and VEGF.RESULTS: HIF-1 alpha and VEGF expression were found in the normal colon tissues by RT-PCR and immunohistochemistry.HIF-1 alpha and VEGF were overexpressed in the lesions of ischemic colitis. Overexpressed HIF-1 alpha and VEGF RNA quickly decreased to the normal level in the scar regions at 7 to 10 d after the occurrence of ischemic colitis.CONCLUSION: Constant expression of HIF-1 alpha and VEGF in normal human colon tissue suggested that HIF-1alpha and VEGF play an important role in maintaining tissue integrity. We confirmed the ischemic crisis in ischemic colitis at the molecular level, demonstrating overexpression of HIF-1 alpha and VEGF in ischemic lesions. These ischemic factors may play an important role in the pathophysiology of ischemic colitis. | Tomoyuki Okuda Takeshi Azuma Masahiro Ohtani Ryuho Masaki Yoshiyuki Ito Yukinao Yamazaki Shigeji Ito Masaru Kuriyama | 2005 | World Journal of Gastroenterology2005，11，10： | 5 |
| 14 | Factors associated with residual gastroesophageal reflux disease symptoms in patients receiving proton pump inhibitor maintenance therapy显示文摘AIM To elucidate the factors associated with residual gastroesophageal reflux disease(GERD) symptoms in patients receiving proton pump inhibitor(PPI) maintenance therapy in clinical practice.METHODS The study included 39 GERD patients receiving maintenance PPI therapy. Residual symptoms were assessed using the Frequency Scale for Symptoms of GERD(FSSG) questionnaire and the Gastrointestinal Symptom Rating Scale(GSRS). The relationships between the FSSG score and patient background factors, including the CYP2C19 genotype, were analyzed.RESULTS The FSSG scores ranged from 1 to 28 points(median score: 7.5 points), and 19 patients(48.7%) had a score of 8 points or more. The patients' GSRS scores were significantly correlated with their FSSG scores(correlation coefficient = 0.47, P < 0.005). In erosive esophagitis patients, the FSSG scores of the CYP2C19 rapid metabolizers(RMs) were significantly higher than the scores of the poor metabolizers and intermediate metabolizers(total scores: 16.7 ± 8.6 vs 7.8 ± 5.4, P < 0.05; acid reflux-related symptom scores: 12 ± 1.9 vs 2.5 ± 0.8, P < 0.005). In contrast, the FSSG scores of the CYP2C19 RMs in the non-erosive reflux disease patients were significantly lower than those of the other patients(total scores: 5.5 ± 1.0 vs 11.8 ± 6.3, P < 0.05; dysmotility symptom-related scores: 1.0 ± 0.4 vs 6.0 ± 0.8, P < 0.01). CONCLUSION Approximately half of the GERD patients receiving maintenance PPI therapy had residual symptoms associated with a lower quality of life, and the CYP2C19 genotype appeared to be associated with these residual symptoms. | Fumiaki Kawara Tsuyoshi Fujita Yoshinori Morita Atsushi Uda Atsuhiro Masuda Masaya Saito Makoto Ooi Tsukasa Ishida Yasuyuki Kondo Shiei Yoshida Tatsuya Okuno Yoshihiko Yano Masaru Yoshida Hiromu Kutsumi Takanobu Hayakumo Kazuhiko Yamashita Takeshi Hirano Midori Hirai Takeshi Azuma | 2017 | World Journal of Gastroenterology2017，23，11： | 5 |
| 15 | A New Species of Huaxiapterus (Pterosauria: Pterodactyloidea) from the Lower Cretaceous of Western Liaoning, China with Comments on the Systematics of Tapejarid Pterosaurs显示文摘tapejarid 翼龙的新种, Huaxiapterus corollatus sp。nov。根据一个将近完全的颅骨被树立并且从辽宁省的更低的 CretaceousJiufotang 形成张贴头部的骨骼,中国。Huaxiapterus corollatus sp。nov。被一个塑造和斧的矩形的过程在切牙骨上描绘,其短轴对 premaxillae 的前面的边缘垂直。除了这个过程,颅骨的另外的人物如此的著名计算机生产厂商他在 nasoantorbital 窗的前面的边缘和切牙骨的前面的边缘之间的猪嘴的宽度类似于 Huaxiapterus jii 的。Huaxiapterus 和第二 Chinesetapejarid, Sinopterus,和 Tapejara 一样的份额几独特头部的人物和这三个类看起来比到另外的 azhdarchoids 与对方有关仔细是更多。Chinesetapejarids (Sinopterus 和 Huaxiapterus ) 相对伸长颅骨和微弱地发达的头部的冠并且似乎少些比 Tapejara 被发源,与它的更短的、更深的颅骨和大头部的冠。Tupuxuarids (Tupuxuara 和 Thalassodromeus ) 经常是在家庭 Tapejaridae 的联系 withtapejarids,但是因为一些种系发生的分析支持了与 Azhdarchidae 配对 tupuxuarids,这种关系是争论的。我们建议 thatTapejaridae 被限制为 Tapejara, Sinopterus 和 Huaxiapterus。 | Lü Junchang JIN Xingsheng David M. UNWIN ZHAO Lijun AZUMA Yoichi JI Qiang | 2006 | Acta Geologica Sinica(English Edition)2006，80，3： | 5 |
| 16 | Delayed perforation after endoscopic submucosal dissection for early gastric cancer: Clinical features and treatment显示文摘Perforation is an important procedural complication of endoscopic submucosal dissection(ESD) for early gastric cancer. Although the incidence of delayed perforation after ESD is low, extreme caution is necessary because many cases require surgical intervention. Among 1984 lesions of early gastric cancer treated in our hospital by ESD in 1588 patients from September 2002 through March 2015, delayed perforation developed in 4 patients(4 lesions, 0.25%). A diagnosis of delayed perforation requires prompt action, including surgical intervention when required. | Takafumi Yano Satoshi Tanabe Kenji Ishido Mizutomo Azuma Takuya Wada Mizuto Suzuki Natsuko Kawanishi Sakiko Yamane Tohru Sasaki Chikatoshi Katada Tetsuo Mikami Natsuya Katada Wasaburo Koizumi | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，8： | 4 |
| 17 | A New Iguanodontian Dinosaur from the Lower Cretaceous Khok Kruat Formation,Nakhon Ratchasima in Northeastern Thailand显示文摘Here we report a new iguanodontian dentary found from the Lower Cretaceous Khok Kruat Formation,Nakhon Ratchasima,northeast Thailand.A unique character,which is an elongated and flat shape of the dentary ramus,makes it possible to assign the specimen to the new genus of non-hadrosaurid iguanodontian,Ratchasimasaurus suranareae gen.et sp.nov.R.suranareae shows both primitive and derived characters,such as a caudally inclined coronoid process and alveolar trough with a primitive crown impression,and a deri... | Masateru SHIBATA Pratueng JINTASAKUL Yoichi AZUMA | 2011 | Acta Geologica Sinica(English Edition)2011，85，5： | 4 |
| 18 | READ-F树脂的除氟性能研究显示文摘通过静态和动态实验,研究了新型除氟树脂READ-F对F-的吸附性能,考察了pH、树脂的用量、通水倍数对该树脂除氟性能的影响,并与改性活性氧化铝(MAA)的除氟性能进行了比较。研究结果表明:pH=4时,临界通水倍数可达3 000;pH=6时,临界通水倍数仅为175。READ-F树脂应在pH≤4时使用。此时出水中溶出的金属离子浓度近似为零,表明该树脂具有良好的耐酸侵蚀性能。原水pH=4时,出水pH随着通水倍数的增大而减小,通水倍数为500时pH最小,然后随着通水倍数的增大而升高。MAA在较低用量(<4 g)时,除氟效率不如READ-F树脂高;但是在较高用量(≥4 g)时,MAA则高于READ-F树脂的除氟效率。 | 王风贺 姜炜 张勇 王力友 Isamu Azuma | 2009 | 工业水处理2009，29，6： | 4 |
| 19 | Argon plasma coagulation for superficial esophageal squamous-cell carcinoma in high-risk patients显示文摘AIM: To evaluate the usefulness and safety of argon plasma coagulation (APC) for superficial esophageal squamous-cell carcinoma (SESC) in high-risk patients. METHODS: We studied 17 patients (15 men and 2 women, 21 lesions) with SESC in whom endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and open surgery were contraindicated from March 1999 through February 2009. None of the patients could tolerate prolonged EMR/ESD or open surgery because of severe concomitant disease (e.g., liver cirrhosis, cerebral infarction, or ischemic heart disease) or scar formation after EMR/ESD and chemoradiotherapy. After conventional endoscopy, an iodine stain was sprayed on the esophageal mucosa to determine the lesion margins. The lesion was then ablated by APC. We retrospectively studied the treatment time, number of APC sessions per site, complications, presence or absence of recurrence, and time to recurrence.RESULTS: The median duration of follow-up was 36 mo (range: 6-120 mo). All of the tumors were macroscopically classified as superficial and slightly depressed type (0-Ⅱc). The preoperative depth of invasion was clinical T1a (mucosal cancer) for 19 lesions and clinical T1b (submucosal cancer) for 2. The median treatment time was 15 min (range: 10-36 min). The median number of treatment sessions per site was 2 (range: 1-4). The median hospital stay was 14 d (range: 5-68 d). Among the 17 patients (21 lesions), 2 (9.5%) had recurrence and underwent additional APC with no subsequent evidence of recurrence. There were no treatment-related complications, such as bleeding or perforation. CONCLUSION: APC is considered to be safe and effective for the management of SESC that cannot be resected endoscopically because of underlying disease, as well as for the control of recurrence after EMR and local recurrence after chemoradiotherapy. | Kumiko Tahara Satoshi Tanabe Kenji Ishido Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Kento Nakatani Akira Naruke Myungchul Kim Wasaburo Koizumi | 2012 | World Journal of Gastroenterology2012，18，38： | 4 |
| 20 | Fukuititan nipponensis,A New Titanosauriform Sauropod from the Early Cretaceous Tetori Group of Fukui Prefecture,Japan显示文摘一条 titanosauriform 恐龙:Fukuititan nipponensis 情报。et sp。nov。基于不完全的骨骼被树立。它被伸长的不对称的牙齿王冠与一条弱或不在的唇音沟并且没有语言的凹度描绘;颈的椎骨的像梗的 epipophysis;肱骨的近似结束的横向的宽度约 32% 肱骨长度;掌部更长,约 48% 半径和 ischia 的远侧的结束稍微膨胀了。它代表从日本发现的第一架相对完全的 titanosauriform 骨骼。Fukuititan 的发现显示差异和 Titanosauriformes 的地理分发比以前的思维高得多。 | Yoichi AZUMA Masateru SHIBATA | 2010 | Acta Geologica Sinica(English Edition)2010，84，3： | 3 |
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