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| 1 | Surgery for colorectal liver metastases: The evolution of determining prognosis显示文摘Despite improvements in the multi-modality treatment of colorectal liver metastasis (CRLM), survival after resection remains varied. Determining prognosis after surgical resection has historically been predicated on preoperative clinicopathological factors such as primary tumor stage, carcinoembryonic antigen levels, number of liver metastases, presence of extrahepatic disease, as well as other factors. While scoring systems have been developed by combining certain preoperative fac- tors, these have been inconsistent in accurately deter- mining prognosis. There has been increasing interest in the use of biologic and molecular markers to predict prognosis following CRLM. The role of markers such as KRAS, BRAF, p53, human telomerase reverse transcrip- tase, thymidylate synthase, Ki-67, and hypoxia inducible factor-1α and their correlation with accurately predict- ing survival after surgical resection have been sup- ported by several studies. Furthermore, other elements such as pathological response to chemotherapy and the presence of circulating tumor cells have shown promise in accurately determining prognosis after resection for colorectal liver metastasis.We herein review past, present, and possible future markers of prognosis among colorectal cancer patients with liver metastasis undergo-ing resection with curative intent. | Gaya Spolverato Aslam Ejaz Nilo Azad Timothy M Pawlik | 2013 | World Journal of Gastrointestinal Oncology2013,5,12: | 7 |
| 2 | In vivo anticancer activity of vanillin semicarbazone显示文摘Objective:To evaluate the anticancer activity of vanillin semicarbazone(VSC) against Ehrlich ascites carcinoma(EAC) cells in Swiss albino mice.Methods:The compound VSC at three doses(5, 7.5 and 10 mg/kg i.p.) was administered into the intraperitoneal cavity of the EAC inoculated mice to observe its efficiency by studying the cell growth inhibition, reduction of tumour weight,enhancement of survival time as well as the changes in depleted hematological parameters. Allsuch parameters were also studied with a known standard drug bleomycin at the dose of 0.3 mg/kg(i.p.).Results:Among the doses studied, 10 mg/kg(i.p.) was found to be quite comparable in potency to that of bleomycin at the dose of 0.3 mg/kg(i.p.). The host toxic effects of VSC was found to be negligible.Conclusions:It can be concluded that VSC can therefore be considered as potent anticancer agent. | Shaikh M Mohsin Ali M Abul Kalam Azad Mele Jesmin Shamim Ahsan M Mijanur Rahman Jahan Ara Khanam M Nazrul Islam Sha M Shahan Shahriar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012,2,6: | 2 |
| 3 | Microprogation and plant regeneration of Rauwolfia serpentina by tissue culture technique显示文摘 | Ahmad S Amin M N Azad M A K | 2002 | PakistanJournal of Biological Sciences2002,5,1: | 1 |
| 4 | Fracture Energy of Weakly Reinforced Concrete Beams显示文摘 | Azad A Mirza M Chan P | | 0,,01: | 1 |
| 5 | New chiral olgopyridines- 4,4 ~ - his ( disaccharide)-functionalized 2,2 ' - bipyridines and 4 ' - (disaccharide) functionalized 2,2 ' : 6 ', 2' terpyridines 显示文摘 | Edwin C C Catherine E H Azad M | 2008 | Carbohydrate Research2008,343,: | 1 |
| 6 | Biofilm vaccine of Aeromonas hydrophila-standardization of dose and duration for oral vaccination of carps 显示文摘 | Azad I S Shanker K M Mohan C V | 1999 | Fish & Shellfish Immunology1999,9,: | 1 |
| 7 | In vitro propagation of rose cultivars显示文摘 | DEBASIS C AZAD M A K DATTA S K | 2000 | Indian Journal of Plant Physiology2000,5,2: | 1 |
| 8 | High impact of 18F-FDG-PET on management and prognostic stratification of newly diagnosed small cell lung cancer显示文摘 | Azad A Chionh F Scott A M | 2010 | Mol Imaging Biol2010,12,4: | 1 |
| 9 | In vitro propagation of rose cultivars显示文摘 | Debasis C Azad M A K Datta S K | 2000 | Indian Journal of Plant Physiology2000,5,2: | 1 |
| 10 | In vitro propagation of rose culti vats显示文摘 | Debasis C Azad M A K Datta S K | 2000 | Indian Journal of Plant Physiology2000,5,2: | 1 |
| 11 | The potassium channel modulator flupir- tine shifts the frequencyresponse function of hippocampal synapses to favor LTD in mice显示文摘 | Azad SC Eder M Simon W | 2004 | Neurosci Lett2004,370,23: | 1 |
| 12 | Plant regeneration through somatic embryogenesis of a medicinal plant, Phellodendron amurense Rupr显示文摘 | Azad M A K Yokota S Begum F Yoshizawa N | 2009 | In Vitro Cellular & Developmental Biology-Plant2009,45,4: | 1 |
| 13 | In vitro propagation of rose cultivars显示文摘 | DEBASIS C AZAD M A K DATTA S K | 2000 | Indian Journal of Plant Physiology2000,5,2: | 1 |
| 14 | In vitropropagation of rose cultivars显示文摘 | Debasis C Azad M A K Datta S K | 2002 | Indian Journal of Plant Physiology2002,5,2: | 1 |
| 15 | A study of the physical sta- bility of wet media-milled fenofibrate suspensions using dynamic equilibrium curves 显示文摘 | Knikek C Azad M A Dave R N | 2013 | Chem Engineer Res Design2013,91,7: | 1 |
| 16 | Fracture energy of weakly reinforced con- crete beams 显示文摘 | Azad A Mirza M Chan P | 1989 | Fatigue and fracture of engineering materials and structures1989,12,1: | 1 |
| 17 | Digital rights management 显示文摘 | AZAD M IYI AHMED A H S ALAM A | 2010 | International Journal of Computer Science and Network Security2010,10,11: | 1 |
| 18 | Deletion mapping and expression in Escherichia coli of the large genomic segment of a birnavirus 显示文摘 | Azad A A Jagadish M N Brown M A | 1987 | Virology1987,161,: | 1 |
| 19 | Metabolic characteristics and oxidative damage to skeletal muscle in broiler chickens ex- posed to chronic heat stress 显示文摘 | Azad M A K Kikusat0 M Maekawa T | 2010 | Comparative Biochemistry and Physiology Part A2010,155,3: | 1 |
| 20 | The ef- fect of K-humate on the nitrate content and accumulation and some yield components in three potato cultivars显示文摘 | Asadi Azad K Mirhadi M J Hassanpanah D | 2010 | Re- search Journal of Environmental Sciences2010,4,5: | 1 |