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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Avian color perception predicts behavioral responses to experimental brood parasitism in chaffinches显示文摘 | Avilés JM Vikan JR Fossoy F Antonov A Moksnes A R(o)skaft E Stokke BG | | 0，，： | 1 |
| 3 | Evaluation of mild acid oxidation treatments for MWCNT functionalization显示文摘 | Aviles F Cauich-Rodriguez J V Moo Tah L | 2009 | Carbon2009，47，13： | 1 |
| 4 | Effects of stress by unfamiliar sounds on carcass and meat traits in bulls from three continental beef cattle breeds at different ageing times 显示文摘 | PENA F AVILES C DOMENECH V | 2014 | Meat Science2014，，98： | 1 |
| 5 | Electrical and piezoresistive properties of multi-walled carbon nanotube/polymer composite films aligned by an electric field显示文摘 | Oliva-Avile's A I Avile's F Sosa V | 2011 | Carbon2011，49，9： | 1 |
| 6 | Piles as barriers for elastic waves显示文摘 | Aviles J Sanchez -Sesma F J | 1983 | Journal of Geoteehnical Engineering Division ASCE1983，109，9： | 1 |
| 7 | Piles as barriers for elastic waves显示文摘 | Avilés J Sánchez-Sesma F J | 1983 | Journal of Geotechnical Engineering1983，109，9： | 1 |
| 8 | Hypokalemia alters sex hormone and gonadotropin levels:evidence that FSH may be required for luteinization显示文摘 | Tejada F Cremades A Aviles M | 1998 | Endocrino Metab1998，38，： | 1 |
| 9 | Foundation isolation from vibration using piles as barriers显示文摘 | Aviles J Sanchez -Sesma F J | 1988 | Journal of Engineering Mechanics ASCE1988，114，11： | 1 |
| 10 | Foundation isolation from vibrations using piles as barriers显示文摘 | Avilés J Sánchez-Sesma F J | 1988 | Journal of Engineering Mechanics1988，114，11： | 1 |
| 11 | Ile-phe dipeptide self-assembly:Clues to amyloid formation显示文摘 | Groot N S Parella T Aviles F X | | 0，，05： | 1 |
| 12 | Piles as barriers for elastic waves显示文摘 | AVILES J SANCHEZ-SESMA F J | 1983 | Journal of Geotechnical Engineering1983，109，9： | 1 |
| 13 | Foundation isolation from vibration using piles as barriers显示文摘 | AVILES J SANCHEZ-SESMA F J | 1988 | Journal of Engineering Mechanics1988，114，11： | 1 |
| 14 | Crackpath in foam cored DCB sandwich fracture specimens显示文摘 | Carlsson L A Matteson R C Aviles F Loup D C | 2005 | Composites Science and Technology2005，65，1516： | 1 |
| 15 | Foundation isolation from vibrations using piles as barriers 显示文摘 | Aviles J Samchez-sesma F J | 1985 | Journal of Engineering Mechanics1985，114，11： | 1 |
| 16 | Complete Amino Acid Analysis of Proteins by Dabsyl Derivatization and Reverse-Phase Liquid Chromatography显示文摘 | Vendrell J and Aviles F X | 1986 | Chromatogr1986，358，： | 1 |
| 17 | Routine invasive strategy within 24 hours of thrombolysis versus ischaemiaguided conservative approach for acute myocardial infarction with ST segment elevation (GRACIA1):a randomised controlled trial显示文摘 | Fernandez Aviles F Alonso J J Castro Beiras A | 2004 | Lancet2004，364，9439： | 1 |
| 18 | Piles as barriers for elastic waves显示文摘 | AVILLES J SANCHEZ-SESMA F J | 1983 | Journal of Geoteehnieal Engineering Division ASCE1983，109，： | 1 |
| 19 | Piles as barriers for elastic waves显示文摘 | Aviles J Sanchez-sesma F J | | 0，，09： | 1 |
| 20 | Foundation isolation from vibrations using piles as barriers显示文摘 | Avilés J Sánchez-Sesma F J | 1988 | Journal of Engineering Mechanics1988，114，11： | 1 |
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