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| 1 | Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation显示文摘BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young children.Clinical and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver transplantation.AIM To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing PLDLT.METHODS We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative complications.The receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/kg.Subsequently,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be analyzed.RESULTS High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up period.During a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the LTr.Over a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection complications.Additionally,Cox hazard regression found that high-volume RBC transfusion increased the mortality risk by 3.031-fold compared to low-volume transfusion.The Kaplan-Meier survival curves of the studied groups were compared using log-rank tests and the analysis showed significantly decreased graft survival,but with no impact in patient survival related to major complications.On the other hand,there was a significant decrease in both graft and patient survival,with high-volume RBC transfusion.CONCLUSION Transfusion of RBC volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short-and long-term postoperative morbidity and mortality after PLDLT. | Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori Eduardo Henrique Giroud Joaquim Joao Seda-Neto Eduardo Antunes da Fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque | 2021 | World Journal of Gastroenterology2021，27，12： | 6 |
| 2 | 黄龙与黄石钙华微生物沉积作用比较研究显示文摘本文通过调查黄龙风景区水体的环境地质特征与微生物群落结构及多样性,并与黄石公园对比分析,探讨了两种特殊地理环境下的微生物群落结构和多样性及其对钙华沉积的影响。结果表明:黄龙沟泉水属于地下冷泉,且景区内覆盖着大量植被,水体中有大量藻类和细菌;黄石公园猛犸象温泉区泉水属于地下热泉,植被覆盖率很低,泉水中微生物多为嗜热菌,藻类较少。黄龙与黄石钙华主要由方解石组成并且微生物参与了钙华的形成过程。微生物对钙华沉积的作用,主要分为模板作用、产物诱导作用和代谢调控作用,对比探讨了特殊地质环境下的微生物对钙华沉积的贡献,指出微生物沉积作用在钙华沉积过程中的重要性,可为黄龙钙华'黑化'防治提供理论依据。 | 董发勤 代群威 饶瀚云 王富东 赵学钦 蒋忠诚 张强 李博文 Alexander IMalov Enrico Capezzuoli Augusto Auler | 2021 | 中国岩溶2021，40，2： | 4 |
| 3 | Arterial pulse pres sure variation predicting fluid responsiveness in critically ill pa- tients显示文摘 | Auler JO Jr Galas FR Sundin MR | 2008 | Shock2008，30，1： | 1 |
| 4 | Pulse pressure variation is comparable with central venous pressure to guide fluid resuscitation in experimental hemorrhagic shack with endotoxemia 显示文摘 | Noel-Morgan J Otsuki DA Auler JO | 2013 | Shock2013，40，4： | 1 |
| 5 | Arterial pulse pressure variation predicting fluid responsiveness in critically ill patitents显示文摘 | Auler JO Jr Galas F R Sundin M R | 2012 | Shoek2012，30，2： | 1 |
| 6 | Clinical evaluation of theflotrac/vigileoTM system for continuous cardiac output monitoring inpatients undergoing regional anesthesia for elective cesarean section:apilot study显示文摘 | Auler JO Jr Torres ML Cardoso MM | 2010 | Clinics(Sao Paulo)2010，65，8： | 1 |
| 7 | Relations among Valencia orange yields with soil and leaf nutrients in northwestern Parana, Brazil 显示文摘 | Fidalski J Auler P A M Tormem V | 2000 | Braz Arch Biol Technol2000，43，4： | 1 |
| 8 | Late quaternary paleoclimate in semi- arid northeastern Brazil from U-series dating of travertine and water-table speleothems显示文摘 | Auler A S Smart P L | 2001 | Quaternary Research2001，55，2： | 1 |
| 9 | Effects of low doses of inhaled nitric oxide combined with oxygen for the evaluation of pulmonary vascular reactivity in patients with pulmonary hypertension 显示文摘 | Azeka E Auler C Kajita L | 2002 | Pediatr Cardiol2002，23，： | 1 |
| 10 | Volume Replacement Therapy during Hip Arthroplasty using Hydroxyethyl Starch (130/0.4) Compared to Lactated Ringer Decreases Allogeneic Blood Transfusion and Postoperative Infection显示文摘 | Adilson Hamaji Ludhmila Hajjar Marcelo Caiero Juliano Almeida Rosana Ely Nakamura Eduardo A Osawa Julia Fukushima Filomena R Galas Jose Otavio Costa Auler Junior | 2013 | Brazilian Journal of Anesthesiology2013，，1： | 1 |
| 11 | Relations among valenciaorange yields with soil and leaf nuIrients in northwestern Parana, Brazil 显示文摘 | Fidalski J Auler P A M Tormem V | 2000 | Brazilian Archives of Biology and Technology2000，43，4： | 1 |
| 12 | Temperature and acid-base balance in coronary bypass grafting with cardiopulmonary bypass,under hypothermia and normothermia显示文摘 | LUZ H L AULER J J | 2002 | Rev Bras Anestesiol2002，52，2： | 1 |
| 13 | Untersuchungen uber die Rolle der Porphyrine bei geschwulstkranken Menschen und Tieren显示文摘 | Auler H Banzer G | 1942 | Z Krebsforsch1942，53，： | 1 |
| 14 | New stationary phase for anion -exchange chromatography 显示文摘 | AULER L M L A SILVA C R COLLINS K E | 2005 | J Chromatogr A2005，1073，： | 1 |
| 15 | Perioperative fluid therapy: a statement from the international Fluid Optimization Group 显示文摘 | Navarro LH Bloomstone JA Auler JO Jr | 2015 | Perioper Med (Lond)2015，4，： | 1 |
| 16 | Alveolar recruitment maneuver to reverse hypoxemia in the immediate postoperative period of cardiac surgery显示文摘 | Auler Jr JOC Nozawa E Toma EK etal | 2007 | RevBras Anestesio12007，57，5： | 1 |
| 17 | Effects of low doses of inhaled nitric oxide combined with oxygen for the evaluation of pulmonary vascular reactivity in patients with pulmonary hypertension 显示文摘 | Azeka E Costa Auler JO Jr Kajita L | 2002 | Pediatr Cardiol2002，23，1： | 1 |
| 18 | Pulse pressure variation is comparable with central venous pressure to guide fluid resuscita- tion in experimental hemorrhagic shock with endotoxemia显示文摘 | Noel-Morgan J Otsuki DA Auler JO | 2013 | Shock2013，40，4： | 1 |
| 19 | Millennial-scale precipi- tation changes in southern Brazil over the past 90, 000 years 显示文摘 | Wang X F Auler A S Edwards R L | 2007 | Geo- physical Research Letters2007，34，23： | 1 |
| 20 | Online monitoring of pulse pressure variation to guide fluid therapy after cardiac surgery 显示文摘 | Auler JO Jr Galas F Hajjar L | 2008 | Anesth Analg2008，106，4： | 1 |
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