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| 1 | Biomechanical characteristics of bone in streptozotocin-induced diabetic rats:An in-vivo randomized controlled experimental study显示文摘AIM: To investigate the in vivo effects of type Ⅰdiabetes on the mechanical strength of tibial bone in a rodent model.METHODS: The biomechanical effect of diabetes on the structural integrity of the tibia in streptozotocin induced diabetic Wistar rats was analysed. Induction of diabetes was achieved by an intra-peritoneal injection and confirmed by measuring serial blood glucose levels(> 150 mg/d L). After 8 wk the tibiae were harvested and compared to a control group. Biomechanical analysis of harvested tibiae was performed using a threepoint bending technique on a servo hydraulic MTS 858 MiniB ionix frame. Maximum force applied to failure(N), stiffness(N × mm) and energy absorbed(N/mm) were recorded and plotted on load displacement curves. A displacement control loading mode of 1 mm/min was selected to simulate quasi-static loading conditions. Measurements from load-displacement curves were directly compared between groups.RESULTS: Fourteen streptozotocin induced diabetic Wistar rats were compared against nineteen non-diabetic controls. An average increase of 155.2 g in body weight was observed in the control group compared with only 5 g in the diabetic group during the experimental study period. Levels of blood glucose increased to 440.25 mg/d L in the diabetic group compared to 116.62 mg/d L in the control group.The biomechanical results demonstrate a highly significant reduction in the maximum load to failure from 69.5 N to 58 N in diabetic group compared to control(P = 0.011). Energy absorption to fracture was reduced from 28.2 N in the control group to 23.5 N in the diabetic group(P = 0.082). No significant differences were observed between the groups for bending stiffness.CONCLUSION: Streptozotocin-induced diabetes in rodents reduces the maximum force and energy absorption to failure of bone, suggesting a predisposition for fracture risk. | Nektarios Korres Eleftherios Tsiridis George Pavlou Athanasios Mitsoudis Despina N Perrea Aristedes B Zoumbos | 2013 | World Journal of Orthopedics2013,4,3: | 2 |
| 2 | Layered Organosilicate Nanoparticles with Liquid-Like Behavior 显示文摘 | Athanasios B Bourlinos Subhendu Ray Chowdhury David D Jiang | 2005 | Small2005,1,1: | 1 |
| 3 | A UTD Propagation Model in Urban Microcellular En- vironments显示文摘 | Athanasios G K Ioannis D K George B K | 1997 | IEEE Transactions on Vehicular Technology1997,46,1: | 1 |
| 4 | A pulmonary rehabili tation program reduces levels of anxiety and depression in COPD patients显示文摘 | Athanasios T Dionisios B Argiro P | 2013 | Multidiseiplinary Respiratory Medicine2013,8,: | 1 |
| 5 | Effect of protein kinase inhibitors on the stretch-elicited c-Fos and c-Jun up-regulation in human PDL osteoblast-like cells显示文摘 | Kletsas D B Efthimia K Athanasios G | 2002 | J Cell Physiol2002,190,3: | 1 |
| 6 | Differentiation between patients with acute upper gastrointestinal bleeding who need early urgent upper gastrointestinal endoscopy and those who do not. A prospective study显示文摘 | Adam B Adamopoulos Nikolaos M Baibas Stamatis P Efstathiou Dimitrios I Tsioulos Athanasios G Mitromaras Amalia A Tsami Theodore D Mountokalakis | 2003 | European Journal of Gastroenterology & Hepatology2003,,4: | 1 |
| 7 | Antibi-otic prophylaxis in cochlear implant surgery显示文摘 | BARRY E H ATHANASIOS B MARK W | 2007 | La-ryngoscope2007,117,: | 1 |
| 8 | A Com- plete Farm Management System Based?on Animal Identification Using? RFID Technology 显示文摘 | ATHANASIOS S CHARALAMPOS Z ALEXANDER B | 2010 | Computers and Electronics in Agriculture2010,70,2: | 1 |
| 9 | Intratympanic andsystemic steroids for sudden hearing loss显示文摘 | Petros K Athanasios B Aristides S | 2013 | Otol Neurotol2013,34,4: | 1 |
| 10 | The use of the ALT flap and lateral femoral cutaneous nerve for the recon-struction of carpal soft tissueand ulnar nerve defects: a case re- port 显示文摘 | Athanasios K Serafeim B Konstantinos A | 2014 | J Hand Microsurg2014,10,8: | 1 |
| 11 | Modeling ap- proach for transit signal preemption 显示文摘 | Agrawal B B Waller S T Athanasios Z | 2002 | Transportation Research Record2002,1791,: | 1 |
| 12 | T3 and cardiac myocyte cell: a theoretical model显示文摘 | Athanasios T Antonios B Antonios L | 2013 | Recent Pat Cardiovasc Drug Discov2013,8,2: | 1 |
| 13 | Graphite oxide: Chemical reduction to graphite and surface modification with primary aliphatic amines and amino acids 显示文摘 | Athanasios B Bourlinos | 2003 | Langmuir2003,19,15: | 1 |
| 14 | Graphite oxide:chemical reduction to graphite and surface modification with primary aliphatic amines and amino acids显示文摘 | Athanasios B Bourlinos Dimitrios | 2003 | Langmuir2003,19,15: | 1 |
| 15 | 以自然的名义显示文摘自人类开始以来,人们就知道从自然中获取灵感和智慧,自然界中形形色色的生物和自然现象,给予人们无限大的提取空间和想象空间。建筑的形成,陶罐的出现,家具的产生,衣服、装饰品的图案等,首先都来自于宇宙天地,日月星辰,飞禽走兽,花草鱼鸟等自然属性和鲜明的个性特征,而这些取自于自然的时尚元素,也为人们的生活增添了无穷的光辉。20世纪80年代开始,由于计算机技术的快速发展和普及以及因特网的迅猛发展,人类进入了一个信息爆炸的新时代,这个巨大的变化同时也改变着人们的生活方式。城市的喧嚣、工业化。 | Athanasios Babalis Béatrice Bruneteau HCWD Studio KiBiSi Luca Nichetto Martín Azúa Milia Seyppel MEJD Studio Pinchdesign Perla Valtierra Tjalle&Jasper Tommaso Caldera Zaven 伏平 范嘉苑 | 2015 | 现代装饰(家居)2015,0,2: | 0 |