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| 1 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 2 | 食管静脉曲张治疗:内镜下硬化和EUS引导下硬化治疗食管侧支静脉的随机对照研究显示文摘Background: Endoscopic sclerotherapy (ES) and band ligation are standard treatments for esophageal varices. Unfortunately, recurrence is common and seems to be related to esophageal collateral vessels, easily identified by EUS. Eradication of these vessels might lead to a more durable therapeutic effect. Objective: To compare ES with EUS-guided sclerotherapy of collateral vessels (EUS-ES). Design: Randomized controlled trial. Setting: Endoscopy Unit, Division of Gastroenterology. Universidade Federal de S o Paulo, S o Paulo, Brazil. Patients and Interventions: Fifty cirrhotic patientswith esophageal varices were randomized into 2 groups: ES (n = 25) and EUS-ES (n = 25). EUS-ES was targeted at collateral veins. Patients were followed-up for at least 6 months after eradication. Main Outcome Measurements: Efficacy in eradication, complications, and recurrence of varices. Results: Varices were eradicated in 48 patients who adhered to the study protocol. The mean (SD) number of sessions until eradication was 4.3 (1.5) for the ES group and 4.1 (1.2) for the EUS-ES group. In ES group, 4 patients had mild bleeding. In EUS-ES group, 4 patients had pain. The mean (SD) length of the follow-up period was 22.6 (6.9) months for the ES group and 24.9 (8.1) months for the EUS-ES group. Recurrence was seen in 4 patients after ES and in 2 after EUS-ES (P = .32). The presence of collateral vessels was associated with recurrence (P = .003). Conclusion: EUS-ES is as safe and effective as ES in variceal eradication. Recurrence tends to be less frequent and occurs later. Persistence of esophageal collateral vessels after sclerotherapy is a risk factor for recurrence. | Andrade De Paulo G. Ardengh J. C. Nakao F. S. Ferrari A.P. 陈瑜(译) 郑世成(校) | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，8： | 4 |
| 3 | Different options of endosonography-guided biliary drainage after endoscopic retrograde cholangiopancreatography failure显示文摘AIM To investigate the success rates of endosonography(EUS)-guided biliary drainage(EUS-BD) techniques after endoscopic retrograde cholangiopancreatography(ERCP) failure for management of biliary obstruction.METHODS From Feb/2010 to Dec/2016, ERCP was performed in 3538 patients, 24 of whom(0.68%) suffered failure to cannulate the biliary tree. All of these patients were initially submitted to EUS-guided rendez-vous(EUS-RV) by means of a transhepatic approach. In case of failure, the next approach was an EUS-guided anterograde stent insertion(EUS-ASI) or an EUS-guided hepaticogastrostomy(EUS-HG). If a transhepatic approach was not possible or a guidewire could not be passed through the papilla, EUS-guided choledochoduodenostomy(EUS-CD) was performed.RESULTS Patients were submitted to EUS-RV(7), EUS-ASI(5), EUS-HG(6), and EUS-CD(6). Success rates did not differ among the various EUS-BD techniques. Overall,technical and clinical success rates were 83.3% and 75%, respectively. Technical success for each technique was, 71.4%, 100%, 83.3%, and 83.3%, respectively(P = 0.81). Complications occurred in 3(12.5%) patients. All of these cases were managed conservatively, but one patient died after rescue percutaneous transhepatic biliary drainage(PTBD).CONCLUSION The choice of a particular EUS-BD technique should be based on patient's anatomy and on whether the guidewire could be passed through the duodenal papilla. | JoséCelso Ardengh César Vivian Lopes Rafael Kemp Jose Sebastiao dos Santos | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，5： | 3 |
| 4 | Conservative management of cholestasis with and without fever in acute biliary pancreatitis显示文摘The presence of cholestasis in both mild and severe forms of acute biliary pancreatitis(ABP)does not justify,of itself,early endoscopic retrograde cholangiography(ERC)or endoscopic sphincterotomy(ES).Clinical support treatment of acute pancreatitis for one to two weeks is usually accompanied by regression of pancreatic edema,of cholestasis and by stone migration to the duodenum in 60%-88%of cases.On the other hand,in cases with both cholestasis and fever,a condition usually characterized as ABP associated with cholangitis,early ES is normally indicated.However,in daily clinical practice,it is practically impossible to guarantee the coexistence of cholangitis and mild or severe acute pancreatitis.Pain,fever and cholestasis,as well as mental confusion and hypotension,may be attributed to inflammatory and necrotic events related to ABP. Under these circumstances,evaluation of the bile duct by endo-ultrasonography(EUS)or magnetic resonance cholangiography(MRC)before performing ERC and ES seems reasonable.Thus,it is necessary to assess the effects of the association between early and opportune access to the treatment of local and systemic inflammatory/infectious effects of ABP with cholestasis and fever, and to characterize the possible scenarios and the subsequent approaches to the common bile duct,directed by less invasive examinations such as MRC or EUS. | JoséSebastio Santos Rafael Kemp JoséCelso Ardengh Jorge Elias Jr | 2012 | World Journal of Gastrointestinal Surgery2012，4，3： | 2 |
| 5 | Single step EUS-Guided endoscopic treatment for sterile pancreatic collec-tions:a single-center experience显示文摘 | Jose C Ardengh Djaima E Coelho Jose F | 2008 | Digestive Diseases2008，26，： | 1 |
| 6 | Treatment of esophageal varices:a randomized controlled trial comparing endoscopic sclerotherapy and EUS-guided sclerotherapy of esophageal collateral veins显示文摘 | Gustavo AD Ardengh JC Nakao FS | | 0，，03： | 1 |
| 7 | Endosonographyguided drainage of pancreatic pseudocyst without gastric or duodenal compression显示文摘 | Ardengh JC Della Libera E Ferrari AP | 1998 | Endoscopy1998，30，： | 1 |
| 8 | Treatment of esophageal varices: a randomized controlled trial comparing endoscopic sclerotherapy and EUS-guided sclerotherapy of esophageal collateral veins <ce:link locator='fx1'/>显示文摘 | Gustavo Andrade de Paulo José Celso Ardengh Frank Shigueo Nakao Angelo Paulo Ferrari | 2006 | Gastrointestinal Endoscopy2006，，3： | 1 |
| 9 | Role of EUS in the preoperative localization of insulinomas compared with spiral CT显示文摘 | Ardengh JC Rosenbaum P Ganc A J | | 0，，： | 1 |
| 10 | Microlithiasis of the gallbladder:role of endoscopic ultrasonography in patients with idio- pathic acute pancreatitis 显示文摘 | Ardengh JC Malheiros CA Rahal F | 2010 | Rev Assoe Med Bras2010，56，1： | 1 |
| 11 | Endo-sonography-guided celiac plexus neurolysis in the treatment of pain secondary to acute intermittent porphyria 显示文摘 | Ferrari AP Ardengh JC | 2002 | Endoscopy2002，34，4： | 1 |
| 12 | Clinicopathologic characteristics and endoscopic treatment of posttraumatic pancreatic pseudocysts 显示文摘 | Coelho DE Ardengh JC Carbalo MT | 2011 | Pancreas2011，40，3： | 1 |
| 13 | Endoscopic ultrasound and fine neeclle aspiration in chronic pancreatitis: differential diagnosis between pseudotumoral masses and pancreatic cancer 显示文摘 | Ardengh JC Lopes CV Campos AD | 2007 | JOP2007，8，4： | 1 |
| 14 | Cell block technique and cytological smears for the differential diagnosis of pancreatic neoplasms after endosonography-guided fine-needle aspiration 显示文摘 | Ardengh JC Lopes CV de Lima LF | 2008 | Acta Gastroenterol Latinoam2008，38，4： | 1 |
| 15 | Identification of insulinomas by endoscopic ultrasonography显示文摘 | Ardengh JC Valiati LH Geocze S | 2004 | Rev Assoc Med Bras2004，50，2： | 1 |
| 16 | Role of EUS in the preoperative localization of insulinoma compared with sp iral CT显示文摘 | Rosenbaum P Ganc J | 2000 | Gastrointest Endosc2000，51，5： | 1 |
| 17 | Role of EUS in the preoperative localization of insulinomas compared with spiral CT 显示文摘 | Ardengh JC Rosenbaum P Ganc A J | 2000 | Gastrointest Endosc2000，51，5： | 1 |
| 18 | Microlithiasis of the gallbladder: role of endoscopic ultrasonography in patients with idiopathic acute pancreatitis 显示文摘 | Ardengh JC Malheiros CA Rahal F | 2010 | Rev Assoc Med Bras2010，56，1： | 1 |
| 19 | Clinicopathologic characteristics and endoscopic treatment of post-traumatic pancreatic pseudocysts显示文摘 | Coelho DE Ardengh JC Carbalo MT | | 0，，03： | 1 |
| 20 | Role of EUS in thepreoperative localization of insulinomas compared with spiralCT 显示文摘 | Ardengh JC Rosenbaum P Ganc AJ | 2000 | Gastrointestinal Endoscopy2000，51，5： | 1 |
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