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| 1 | Sarcopenia and non-alcoholic fatty liver disease:Is there a relationship?A systematic review显示文摘AIM To perform a systematic review to evaluate the incidence and prevalence of non-alcoholic fatty liver disease(NAFLD) in adult patients with sarcopenia.METHODS Randomized clinical trials,cross-sectional or cohort studies including adult patients(over 18 years) with sarcopenia were selected.The primary outcomes of interest were the prevalence or incidence of NAFLD in sarcopenic patients.In the screening process,44 fulltext articles were included in the review and 41 studies were excluded.RESULTS Three cross-sectional studies were included.The authors attempted to perform a systematic review,but due to the differences between the studies,a qualitative synthesis was provided.The diagnosis of NAFLD was made by non-invasive methods(image methods or any surrogate markers) in all three evaluated studies.All the studies suggested that there was an independent association between sarcopenia and NAFLD.CONCLUSION Sarcopenia is independently associated with NAFLD and possibly to an advanced fibrosis. | Cristiane V Tovo Sabrina A Fernandes Caroline Buss Angelo A de Mattos | 2017 | World Journal of Hepatology2017，9，6： | 9 |
| 2 | Influence of proton pump inhibitors in the development of spontaneous bacterial peritonitis显示文摘AIM To investigate whether the use of proton pump inhibitors(PPIs) increases the incidence of spontaneous bacterial peritonitis(SBP) in patients with cirrhosis and ascites.METHODS An historical cohort study was carried out in cirrhotic outpatients with ascites followed in a specialized clinic at a tertiary hospital in Southern Brazil. Patient charts were reviewed to collect information on the variables of interest as the use of PPIs. Primary outcome was defined as development of SBP during the study period. SBP was diagnosed based on ascitic fluid polymorphonuclear cell count ≥ 250 cells/mm3 without evidence of an intraabdominal, surgically treatable source of infection.RESULTS Of 738 cirrhotic patients, 582(58.2% male) were enrolled, with mean age of 53.6 ± 12 years. Hepatitis C virus infection(36.2%) and alcohol abuse(25.6%) were the main etiologies of cirrhosis. The presence of ascites was detected in 299(51.4%) patients during the development of the study. Nineteen patients with previous diagnosis of SBP undergoing secondary prophylaxis and 22 patients with insufficient PPI data were further excluded. Of 258 patients with ascites, 151 used PPIs, and 34 developed SBP(22.5%). Among 107 non-users of PPIs, 23 developed SBP(21.5%)(HR = 1.44, 95%CI: 0.85-2.47, P = 0.176). The median follow-up time of patients using PPI was 27 mo vs 32 mo for non-users. Univariate analysis of the risk factors associated with the development of SBP revealed a significant association of SPB with the severity of liver disease according to the Child-Turcotte-Pugh(CTP) score. Multivariate analysis confirmed that CTP score was the only independent variable influencing the occurrence of SBP. Survival at 60 mo(Kaplan-Meier analysis) was similar in users and non-users of PPI, independently of the presence of SBP(58.4% vs 62.7% respectively, P = 0.66). For patients with SBP, survival at 60 mo was 55.1%, vs 61.7% in patients without SBP(P = 0.34). CONCLUSION In conclusion, the rate of SBP was not significantly different in users or non-users of PPIs in this cohort of cirrhotic with ascites. | Suelen A S Miozzo Jorge A John Marcelo C Appel-da-Silva Isabella A Dossin Cristiane V Tovo Angelo A Mattos | 2017 | World Journal of Hepatology2017，9，35： | 5 |
| 3 | Assessing Public-privateResearch Collaboration:is it Possible to Compare University Per-formance显示文摘 | Abramo G D'Angelo C A Solazzi M | 2010 | Scientometrics2010，84，1： | 1 |
| 4 | Wet air oxidation of caustic liquors显示文摘 | De Angelo D J Wilhehni A R | 1983 | Chemical Engineering Process1983，79，3： | 1 |
| 5 | Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia显示文摘 | Kristi A Sacco Angelo Termine Aisha Seyal | 2005 | Arch Gen Psychiatry2005，62，6： | 1 |
| 6 | Identification of lipoxygenase linoleate decomposition products by direct gas chromatography-mass spectrometry显示文摘 | Angelo A J Legendre M G Dupuy H P | 1980 | Lipids1980，15，： | 1 |
| 7 | Vascular endothelial growth factors and angiogenesis显示文摘 | Frelin C Ladoux A D'angelo G | | 0，，： | 1 |
| 8 | Creep and recovery显示文摘 | D Angelo J A R Dongre G Reinke | 2007 | Public roads2007，，70： | 1 |
| 9 | Hepatocellular carcinoma in non-alcoholic steatohepatitis without cirrhosis显示文摘Cirrhosis is an emerging major cause of the development of hepatocellular carcinoma(HCC),but in non-alcoholic fatty liver disease(NAFLD),up to 50%of patients with HCC had no clinical or histological evidence of cirrhosis.It is currently challenging to propose general recommendations for screening patients with NAFLD without cirrhosis,and each patient should be evaluated on a caseby-case basis based on the profile of specific risk factors identified.For HCC screening in NAFLD,a valid precision-based screening is needed.Currently,when evaluating this population of patients,the use of non-invasive methods can guide the selection of those who should undergo a screening and surveillance program.Hence,the objective of the present study is to review the epidemiology,the pathophysiology,the histopathological aspects,the current recommendations,and novel perspectives in the surveillance of non-cirrhotic NAFLD-related HCC. | Cristiane Valle Tovo Angelo Zambam de Mattos Gabriela Perdomo Coral Giovana D P Sartori Livia Villela Nogueira Gustavo Tovo Both Cristiane A Villela-Nogueira Angelo A de Mattos | 2023 | World Journal of Gastroenterology2023，29，2： | 1 |
| 10 | Relationship between homocysteine and thrombotic disease显示文摘 | Selhub J D' angelo A | 1998 | Am J Med Sci1998，316，2： | 1 |
| 11 | Association studies of genetic polymorphisms and complex disease显示文摘 | Gambaro G Anglani F D'Angelo A | 2000 | Lancet2000，355，： | 1 |
| 12 | Analysis of Lipids from Cooked Beef by Thin-layerChromatography with Flame-ionization Detection显示文摘 | St Angelo A J James Jr C | 1993 | JAOCS1993，70，12： | 1 |
| 13 | Hydrodynamical modeling of charge carrier transport in semiconductors显示文摘 | Angelo M A Vittorio R | 2000 | Overviews and Tutorials2000，35，： | 1 |
| 14 | Consumer credit and consump- tion forecasts显示文摘 | Angelos A Antzoulatos | 1996 | International journal of forecasting1996，，12： | 1 |
| 15 | 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy显示文摘 | Michele B Angelo A Gonzalo BE | 2013 | Eu- ropean Heart Journal2013，，34： | 1 |
| 16 | Tollip is a mediator of protein sumoylation显示文摘 | Ciarrocchi A D Angelo R Cordiglieri C | 2009 | PLoS One2009，4，2： | 1 |
| 17 | Relationship between homocysteine and thrombotic disease 显示文摘 | Selhub J d'Angelo A | 1998 | Am J Med Sci1998，316，2： | 1 |
| 18 | Successful treatment of recalcitrant genital ulcers of Behcet's disease with adalimumab after fail- ure of infliximab and elanereept 显示文摘 | Olivieri I D'Angelo S Padula A | 2009 | Clin Exp Rheumatol2009，27，2153： | 1 |
| 19 | IL-22 defines a novel immune pathway of antifungal resistance显示文摘 | De Luca A Zelante T D'Angelo C | | 0，，： | 1 |
| 20 | Therapeutic outcome according to histologic subtype in 121 patients with malignant pleural mesothelioma显示文摘 | Giovanni Luca Ceresoli Laura Deborah Locati Andrés José Mar??a Ferreri Cesare Cozzarini Paolo Passoni Giulio Melloni Piero Zannini Angelo Bolognesi Eugenio Villa | 2001 | Lung Cancer2001，，2： | 1 |
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