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| 1 | Cytomegalovirus frequency in neonatal intrahepatic cholestasis determined by serology, histology, immunohistochemistry and PCR显示文摘AIM: To determine cytomegalovirus (CMV) frequency in neonatal intrahepatic cholestasis by serology, histological revision (searching for cytomegalic cells), immunohistochemistry, and polymerase chain reaction (PCR), and to verify the relationships among these methods.METHODS: The study comprised 101 non-consecutive infants submitted for hepatic biopsy between March 1982 and December 2005. Serological results were obtained from the patient's f iles and the other methods were performed on paraffin-embedded liver samples from hepatic biopsies. The following statistical measures were calculated: frequency, sensibility, specif ic positive predictive value, negative predictive value, and accuracy.RESULTS: The frequencies of positive results were as follows: serology, 7/64 (11%); histological revision, 0/84; immunohistochemistry, 1/44 (2%), and PCR, 6/77 (8%). Only one patient had positive immunohistochemical fi ndings and a positive PCR. The following statistical measures were calculated between PCR and serology: sensitivity, 33.3%; specificity, 88.89%; positive predictive value, 28.57%; negative predictive value, 90.91%; and accuracy, 82.35%. CONCLUSION: The frequency of positive CMV varied among the tests. Serology presented the highest positive frequency. When compared to PCR, the sensitivity and positive predictive value of serology were low. | Maria Angela Bellomo-Brandao Paula D Andrade Sandra CB Costa Cecilia AF Escanhoela Jose Vassallo Gilda Porta Adriana MA De Tommaso Gabriel Hessel | 2009 | World Journal of Gastroenterology2009，15，27： | 8 |
| 2 | Comparison of two clinical scales for causality assessment in hepatotoxicity显示文摘 | Ma Isabel Lucena Raquel Camargo Raúl J. Andrade Carlos J. Perez-Sanchez Felipe Sanchez De La Cuesta | 2001 | Hepatology2001，，1： | 2 |
| 3 | Novel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways 显示文摘 | Fox EM Andrade J Shupnik MA | 2009 | Steroids2009，74，7： | 1 |
| 4 | Echinococcus multilocularis laminatcd?layer components and the E14t 14-3-3recombinant protein decrease NO production by activated rat macrophages in vitro显示文摘 | Andrade MA Siles-Lucas M Espinoza E | 2004 | Nitric Oxide2004，10，3： | 1 |
| 5 | Elevated IL - 1 f3 and IL -6 levels in lumbar herniated discs in patients with sciatic 显示文摘 | Andrade P Hoogland G Garcia MA | 2013 | Eur Spine J2013，22，4： | 1 |
| 6 | Immunoexpression of interleukin 17,transforming growth factor β1,and forkhead box P3 in periapicalgranulomas,radicular cysts,and residual radicular cysts 显示文摘 | Andrade AL Nonaka CF Gordon-Núnez MA | 2013 | J Endod2013，39，8： | 1 |
| 7 | Elevated IL- 6 显示文摘 | Andrade P Hoogland G Garcia MA | 2013 | Eur Spine J2013，22，4： | 1 |
| 8 | A review of 128 cases of posterior mediastinal goiter 显示文摘 | De Andrade MA | 1997 | World J Surg1997，1，6： | 1 |
| 9 | Use of prescription med- ications with a potential for fetal harm among pregnant women 显示文摘 | Andrade SE Raebel MA Morse AN | 2006 | Phanmwoeidemiol Drug Saf2006，15，8： | 1 |
| 10 | Comparison of ARM and HEAT protein repeats显示文摘 | Andrade MA Petosa C O'Donoghue SI | 2001 | J Mol Bio12001，309，1： | 1 |
| 11 | Humanization health at emer- gency service in a public hospital :comparison on social representation of professional before and after training 显示文摘 | Andrade MA Artmann E Trindade ZA | 2011 | Cien Saude Colet2011，16，1： | 1 |
| 12 | Iatrogenic bile duct injuries显示文摘 | Savassi-Rocha PR Almeida SR Sanches MD Andrade MA | 2003 | Surg Endosc2003，17，： | 1 |
| 13 | Association of genes to genetically inherited diseases using data mining 显示文摘 | Perez-Iratxeta C Bork P Andrade MA | 2002 | Letter to Namm Genetics2002，31，3： | 1 |
| 14 | Review on nanostructured photoelectrodes for next generation dye- sensitized solar cells显示文摘 | J Ma~aira L Andrade A Mendes | 2013 | Renewable and Sustainable Energy Reviews2013，27，6： | 1 |
| 15 | Automated genome sequence analysis and annotation显示文摘 | Brown NP Leroy C | 1999 | Bioinformatics1999，15，5： | 1 |
| 16 | Mortality rate in patients with nosocomial Acinetobacter men-ingitis from a Brazilian hospital显示文摘 | Tuon FF Penteado-Filho SR Amarante D Andrade MA BorbaLA | 2010 | Braz J Infect Dis2010，14，5： | 1 |
| 17 | A prospective study ofrisk factors for cardiovascular events among the elderly 显示文摘 | Cabrera MA de Andrade SM Mesas AE | 2012 | ClinInterv Aging2012，7，： | 1 |
| 18 | Echinococcus multilocularis laminated-layer components and the E14t 14-3-3recombinant protein decrease NO production by activated rat macrophages in vitro显示文摘 | Andrade MA Siles-Lucas M Espinoza E | 2004 | Nitric Oxide2004，10，： | 1 |
| 19 | A prospective study of risk factors for cardiovascular events among the elderly 显示文摘 | Cabrera MA Andrade SM Mesas AE | 2012 | Clin Interv Aging2012，7，： | 1 |
| 20 | Serum leptin levels in normal children: relationship to age, gender, body mass index, pituitry-gonadal hormones and pubertal stage 显示文摘 | Garcia-Mayor RV Andrade MA Rios M | 1997 | J Clin Endocrinol Metab1997，82，9： | 1 |
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