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| 1 | Parathyroid ultrasonography and bone metabolic profile of patients on dialysis with hyperparathyroidism显示文摘AIM To evaluate the parathyroid ultrasonography and define parameters that can predict poor response to treatment in patients with secondary hyperparathyroidism due to renal failure.METHODS This cohort study evaluated 85 patients with chronic kidney disease stage V with parathyroid hormone levels above 800 pg/mL. All patients underwent ultrasonography of the parathyroids and the following parameters were analyzed: Demographic characteristics(etiology of chronic kidney disease, gender, age, dialysis vintage, vascular access, use of vitamin D), laboratory(calcium, phosphorus, parathyroid hormone, alkaline phosphatase, bone alkaline phosphatase), and the occurrence of bone changes, cardiovascular events and death. The χ~2 test were used to compare proportions or the Fisher exact test for small sample frequencies. Student t-test was used to detect differences between the two groups regarding continuous variables.RESULTS Fifty-three patients(66.4%) had parathyroid nodules with higher levels of parathyroid hormone, calcium and phosphorus. Sixteen patients underwent parathyroidectomy and had higher levels of phosphorus and calcium × phosphorus product(P = 0.03 and P = 0.006, respectively). They also had lower mortality(32% vs 68%, P = 0.01) and lower incidence of cardiovascular or cerebrovascular events(27% vs 73%, P = 0.02). Calcium × phosphorus product above 55 mg^2/dL^2 [RR 1.48(1.06, 2.08), P = 0.03], presence of vascular calcification [1.33(1.01, 1.76), P = 0.015] and previous occurrence of vascular events [RR 2.25(1.27, 3.98), P < 0.001] were risk factors for mortality in this population. There was no association between the occurrence of nodules and mortality.CONCLUSION The identification of nodules at ultrasonography strengthens the indication for parathyroidectomy in patients with secondary hyperparathyroidism due to renal failure. | Cláudia Ribeiro Maria Goretti Moreira Guimaraes Penido Milena Maria Moreira Guimaraes Marcelo de Sousa Tavares Bruno das Neves Souza Anderson Ferreira Leite Leonardo Martins Caldeira de Deus Lucas Joséde Campos Machado | 2016 | World Journal of Nephrology2016，5，5： | 2 |
| 2 | Pharmacoge- netie characteristics of indinavir, zidovudine, and lamivudi- ne therapy in HIV-infeeted adults: a pilot study 显示文摘 | Anderson PL Lamba J Aquilante CL | 2006 | J Ac-quir lmmune Defic syndr2006，42，4： | 1 |
| 3 | Phosphoinositide 3-kinases and the regulation of platelet function显示文摘 | Jackson SP Yap CL Anderson KE | 2004 | Bioehem Soe Trans2004，32，2： | 1 |
| 4 | Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone显示文摘 | Mendenhall CL Anderson S Garcia-Pont P | 1984 | N Engl J Med1984，311，23： | 1 |
| 5 | Prospertive evaluation of emergency physician perfomed bedside ultrasound to detect acute appendicitis 显示文摘 | Fox JC Solley M Anderson CL | 2008 | Eur J emery Med2008，15，2： | 1 |
| 6 | Induced paternal effects mimic cytoplasmic incompatibility in Drosophila显示文摘 | Clark ME Heath BD Anderson CL | 2006 | Genetics2006，173，2： | 1 |
| 7 | Manganese exposure inhibits the clearance of extracellular GABA and influences taurine homeostasis in the striatum of developing rats显示文摘 | Fordahl SC Anderson JG Cooney PT Weaver TL Colyer CL Eriksun KM | 2010 | Neurotoxicology2010，31，6： | 1 |
| 8 | Trends in incidence ratesof invasive lobular and ductal breast carcinoma显示文摘 | Li Cl Anderson BO Daling JR | 2003 | JAMA2003，289，11： | 1 |
| 9 | Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin:a Southwest Oncology Group Study显示文摘 | Anderson JE Kopechy KJ Willman Cl | 2002 | Blood2002，100，12： | 1 |
| 10 | Insulin - like biologicalac- tivity of culinary and medicinal plant aqueous extracts in -vitro显示文摘 | Broadhurst CL Polansky MM Anderson RA | 2000 | J A- gfic Food Chem2000，48，3： | 1 |
| 11 | A1opecia mucinosa : report of a case and review显示文摘 | Anderson BE Mackley CL Helm KF | 2003 | J Cutan Med Surg2003，7，2： | 1 |
| 12 | CDD: a Conserved Domain Database for the functional annotation of proteins 显示文摘 | Marchler-Bauer A Lu S Anderson JB Chitsaz F Derbyshire MK Weese-Scott CD Fong JH Geer LY Geer RC Gonzales NR Gwadz M Hurwitz DI Jackson JD Ke Z Lanczycki CJ Lu F Marchler GH Mullokandov M Omelchenko MV Robertson CL Song JS Thanki N Yamashita RA Zhang D Zhang N Zheng C Bryant SH | 2011 | Nucleic Acids Res2011，39，： | 1 |
| 13 | Epigenetic predisposition to expression of TIMPI from the human inactive X chromosome 显示文摘 | Anderson CL Brown CJ | 2005 | BMC Genet2005，6，1： | 1 |
| 14 | Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins显示文摘 | Anderson L Hunter CL | | 0，，04： | 1 |
| 15 | A new method to enhance contrast of ultrathin cryosections for immunoelectron microscopy显示文摘 | Takizawa T Anderson CL Robinson JM | | 0，，01： | 1 |
| 16 | Platelet transfusion for patients with cancer: clinical practice guidelines of the Ameri- can Society of Clinieal Oneology 显示文摘 | Schiffer CA Anderson KC Bennett CL | 2007 | J Clin Oneol2007，19，5： | 1 |
| 17 | Platelet transfusion for patients with cancer:clinical practice guidelines of the American Society of Clinical Oncology显示文摘 | Schiffer CA Anderson KC Bennet CL | 2001 | J Clin Oncol2001，19，： | 1 |
| 18 | Multi-component immunoaffinity subtraction chromatography: an innovative step towards a comprehensive survey of the human plasma proteome显示文摘 | Pieper R Su Q Gatlin CL Huang ST Anderson NL Steiner S | 2003 | Proteomic2003，3，4： | 1 |
| 19 | Polymorphic X - chromosome inactivation of the human TIMPI gene 显示文摘 | Anderson CL Brown CJ | 1999 | Am J Hum Genet1999，65，3： | 1 |
| 20 | Platelet transfusion for patients with cancer: clinical peactice guidelies of the American Society of Clinical Oncology显示文摘 | Schiffer CA Anderson KC Bennett CL el al | 2001 | J Clin Oncol2001，19，： | 1 |
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