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| 1 | 英语拒绝策略的可教性实证研究显示文摘英语拒绝策略教学的准实验、定性和定量相结合研究的的是为了检验语用能力的可教性。92人参加了本实验,32人为明示教学组、30人为暗示教学组、30人为控制组,书面话语完成测试、角色扮演和书面自我报告为数据收集工具。结果表明,通过系统教学训练,学习者可学会恰当的英语拒绝表达方式,明示教学比暗示教学效果好,同时延迟记忆也能保持到学习后两个月。 | 段玲琍 Anchalee Wannaruk | 2008 | 四川外语学院学报2008，24，3： | 11 |
| 2 | Autoimmune hepatitis in human immunodeficiency virus-infected patients: A case series and review of the literature显示文摘BACKGROUND Abnormal liver chemistry is a common problem in human immunodeficiency virus (HIV)-infected patients. Common causes of abnormal liver enzymes in this population include viral hepatitis B/C or opportunistic infection, drug toxicity, and neoplasm. Autoimmune hepatitis is a rare cause of hepatitis in HIV-infected individuals;however, this condition has been increasingly reported over the past few years. CASE SUMMARY We present 13 HIV-infected patients (5 males and 8 females) who developed autoimmune hepatitis (AIH) after their immune status was restored, i.e. all patients had stable viral suppression with undetectable HIV viral loads, and median CD4+ counts of 557 cells/× 106 L. Eleven patients presented with chronic persistent elevation of aminotransferase enzyme levels. One patient presented with acute hepatitis and the other patient presented with jaundice. The median levels of aspartate aminotransferase and alanine aminotransferase enzymes were 178 and 177 U/mL, respectively. Elevation of immunoglobulin G levels was present in 11 (85%) patients. Antinuclear antibody and anti-smooth muscle antibody were positive in 11 (85%) and 5 (38%) patients. Liver biopsy was performed in all patients. They had histopathological findings compatible with AIH. The patients were started on prednisolone for remission induction, with good response. After improvement of the liver chemistry, the dose of prednisolone was tapered, and azathioprine was added as life-long maintenance therapy. At the last follow-up visit, all were doing well, without HIV viral rebound or infectious complications. CONCLUSION This report underscores the emergence of autoimmune hepatitis in the context of HIV infection. | Roongruedee Chaiteerakij Anapat Sanpawat Anchalee Avihingsanon Sombat Treeprasertsuk | 2019 | World Journal of Gastroenterology2019，25，35： | 7 |
| 3 | Annexin A1: A new immunohistological marker of cholangiocarcinoma显示文摘AIM: To evaluate a new immunohistological marker, annexin A1 (ANXA1), in cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC). METHODS: Expression of ANXA1 protein was investigated in liver tissues from patients with CCA and HCC by immunohistochemistry. Its expression on differences stages of tumor development was investigated in hamster CCA tissues induced by Opisthorchis viverrini and N -nitrosodimethylamine. Moreover, mRNA expression of ANXA1 was assessed in CCA cell lines by quantitative real-time polymerase chain reaction and silencing of ANXA1 gene expression using small interfering RNA. RESULTS: In human CCA tissue arrays, immunohistochemical analysis revealed that the positive expression of ANXA1 was 94.1% (64/68 cases) consisting of a high expression (66.2%, 45/68 cases) and a low expression (33.8%, 23/68 cases). However, expression of ANXA1 protein was negative in all histologic patterns for HCC (46/46 cases) and healthy individuals (6/6 cases). In hamster with opisthorchiasis-associated CCA, the expression of ANXA1 was observed in the cytoplasm of inflammatory cells, bile duct epithelia and tumor cells. Grading scores of ANXA1 expression were significantly increased with tumor progression. In addition, mRNA expression of ANXA1 significantly increased in all of the various CCA cell lines tested compared to an immortalized human cholangiocyte cell line (MMNK1). Suppressing the ANXA1 gene significantly reduced the matrix metalloproteinase (MMP) 2 and MMP9, and transforming growth factor-β genes, but increased nuclear factor-kB gene expression. CONCLUSION: ANXA1 is highly expressed in CCA, but low in HCC, suggesting it may serve as a new immunohistochemical marker of CCA. ANXA1 may play a role in opisthorchiasis-associated cholangiocarcinogenesis. | Nuttanan Hongsrichan Rucksak Rucksaken Yaovalux Chamgramol Porntip Pinlaor Anchalee Techasen Puangrat Yongvanit Narong Khuntikeo Chawalit Pairojkul Somchai Pinlaorr | 2013 | World Journal of Gastroenterology2013，19，16： | 4 |
| 4 | The possible role of penaeidin5 from the black tiger shrimp, Penaeus monodon , in protection against viral infection显示文摘 | Noppawan Woramongkolchai Premruethai Supungul Anchalee Tassanakajon | 2011 | Developmental and Comparative Immunology2011，，5： | 1 |
| 5 | Molecular cloning, genomic organization and antibacterial activity of a second isoform of antilipopolysaccharide factor (ALF) from the mud crab 显示文摘 | Chanprapa Imjongjirak Piti Amparyup Anchalee Tas- sanakajon | 2011 | Scylla paramamosain Fish or Shellfish Immunology2011，30，1： | 1 |
| 6 | Prophenoloxidase system and its role in shrimp immune responses against major pathogens 显示文摘 | Amparyup Piti Charoensapsri Walaiporn Tassanakajon Anchalee | 2013 | Fish & Shellfish Immunology2013，34，： | 1 |
| 7 | Two prophenoloxidases are important for the survival of Vibrioharveyi challenged shrimp Penaeus monodon显示文摘 | Piti A Walaiporn C Anchalee T | 2009 | Developmental and Comparative Immunology2009，33，： | 1 |
| 8 | A five-domain Kazal-type serine proteinase inhibitor from black tiger shrimp Penaeus monodon and its inhibitory activities显示文摘 | Nawarat S Vichien R Anchalee T | 2006 | Developmental and Comparative Immunology2006，30，11： | 1 |
| 9 | Two novel antimicrobial peptides, arasin-like Sp and GRP Sp , from the mud crab Scylla paramamosain , exhibit the activity against some crustacean pathogenic bacteria显示文摘 | Chanprapa Imjongjirak Piti Amparyup Anchalee Tassanakajon | 2011 | Fish and Shellfish Immunology2011，，2： | 1 |
| 10 | Two prophenoloxidases are important for the survival of Vibrio harveyi challenged shrimp Penaeus monodon显示文摘 | Piti Amparyup Walaiporn Charoensapsri Anchalee Tassanakajon | 2008 | Developmental and Comparative Immunology2008，，2： | 1 |
| 11 | A Comparison of Dexmedetomidine Versus Propofol on Hypotension During Colonoscopy Under Sedation显示文摘 | Anchalee T Tewarux V Chuleeporn S | 2012 | J Anesth Clin Res2012，24，3： | 1 |
| 12 | Phyllanthus acidus(L.) Skeels and Rhinacanthus nasutus(L.) Kurz leaf extracts suppress melanogenesis in normal human epidermal melanocytes and reconstitutive skin culture显示文摘Objective: To determine the effect of extracts from Phyllanthus acidus(P. acidus)(L.) Skeels and Rhinacanthus nasutus(R. nasutus)(L.) Kurz leaves on melanogenesis and the underlying mechanism in normal human epidermal melanocytes(NHEM) and a reconstitutive skin model. Methods: NHEM and a reconstitutive skin model were stimulated with ethanol extracts of P. acidus(L.) Skeels and R. nasutus(L.) Kurz leaves. mRNA expression of microphthalmiaassociated transcription factor(MITF), tyrosinase(TYR), tyrosinase-related protein 1(TYRP1) and dopachrome tautomerase(DCT) were examined by real-time PCR. The melanin content in NHEM was also measured. Moreover, protein levels of tyrosinase were determined using western blot analysis.Results: In NHEM and the reconstitutive skin model, ethanol extracts from P. acidus(at 12.5 and 25.0 μg/mL) and R. nasutus(at 6.25 and 12.50 μg/mL) significantly diminished mRNA expression of MITF, TYR, TYRP1 and DCT in a concentration-dependent manner. P. acidus and R. nasutus extracts also reduced the amount of melanin in α-MSH-stimulated NHEM. Moreover, P. acidus and R. nasutus extracts markedly suppressed tyrosinase at the translational level in the reconstitutive skin model. Conclusions: P. acidus and R. nasutus extracts significantly reduced melanogenesis in NHEM and the reconstitutive skin model, suggesting that P. acidus and R. nasutus extracts can inhibit melanin synthesis through downregulation of MITF, TYR, TYRP1 and DCT. Therefore, the ethanol extracts of P. acidus and R. nasutus contain compounds that have the potential for development as a skin lightening agent for the treatment of hyperpigmentation disorder or melasma. | Moragot Chatatikun Takeshi Yamauchi Kenshi Yamasaki Anchalee Chiabchalard Setsuya Aiba | 2019 | Asian Pacific Journal of Tropical Medicine2019，12，3： | 1 |
| 13 | Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone显示文摘 | Wasana Pratchayasakul Sasiwan Kerdphoo Petnoi Petsophonsakul Anchalee Pongchaidecha Nipon Chattipakorn Siriporn C. Chattipakorn | 2011 | Life Sciences2011，，13： | 1 |
| 14 | Sexual Behavior and Risk Factors for HIV Infection Among Homosexual and Bisexual Men in Thailand显示文摘 | Andrea Li Anchalee Varangrat Wipas Wimonsate | 2009 | AIDS Behav2009，13，： | 1 |
| 15 | R219K Polymorphism of ATP Binding Cassette Transporter A1 Related with Low HDL in Overweight/Obese Thai Males显示文摘 | Anong K Hathairad H Anchalee T | 2007 | Arch Med Res2007，38，： | 1 |
| 16 | Shrimp single WAP domain (SWD)-containing protein exhibits proteinase inhibitory and antimicrobial activities显示文摘 | Piti Amparyup Suchao Donpudsa Anchalee Tassanakajon | 2008 | Developmental and Comparative Immunology2008，，12： | 1 |
| 17 | Molecular cloning, genomic organization and recombinant expression of a crustin-like antimicrobial peptide from black tiger shrimp Penaeus monodon显示文摘 | Piti Amparyup Hidehiro Kondo Ikuo Hirono Takashi Aoki Anchalee Tassanakajon | 2007 | Molecular Immunology2007，，4： | 1 |
| 18 | Discovery of immune molecules and their crucial functions in shrimp immunity显示文摘 | ANCHALEE T KUNLAYA S PREMRUETHAI S | 2013 | Fish & Shellfish Immunology2013，34，4： | 1 |
| 19 | Cloning, expression and antimicrobial activity of crustin Pm 1, a major isoform of crustin, from the black tiger shrimp Penaeus monodon显示文摘 | Premruethai Supungul Sureerat Tang Cherdsak Maneeruttanarungroj Vichien Rimphanitchayakit Ikuo Hirono Takashi Aoki Anchalee Tassanakajon | 2007 | Developmental and Comparative Immunology2007，，1： | 1 |
| 20 | Antilipopolysaccharide factor (ALF) of mud crab Scylla paramamosain : Molecular cloning, genomic organization and the antimicrobial activity of its synthetic LPS binding domain显示文摘 | Chanprapa Imjongjirak Piti Amparyup Anchalee Tassanakajon Siriporn Sittipraneed | 2007 | Molecular Immunology2007，，12： | 1 |
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