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| 1 | Changes of total antioxidant capacity and total oxidant status of aqueous humor in diabetes patients and correlations with diabetic retinopathy显示文摘AIM:To measure changes of total oxidant status(TOS)and total antioxidant capacity(TAC) of aqueous humor(AH) in diabetic retinopathy(DR) patients,and to determine if there were any differences in TOS and TAC of AH in diabetic patients without retinopathy compared with non-diabetic patients.·METHODS:One hundred and three eyes of 103patients who were enrolled for cataract surgery were included in this study.Patients were grouped according to presence of diabetes and stage of DR.Prior to cataract surgery,0.1mL to 0.2mL of AH was aspirated and analyzed for TAC and TOS level using a colorimetric method.·RESULTS:TOS levels were highest among proliferative diabetic retinopathy(PDR) patients and lowest in patients with only cataracts.Results were statistically significant between all groups(P <0.05).Whereas result between diabetic without retinopathy patients and non-proliferative diabetic retinopathy(NPDR) patients was not statistically significant(P =0.757).TAC levels were highest in patients with only cataract and lowest among PDR patients and results were statistically significant between all groups(P <0.05).·CONCLUSION:Aqueous humor TAC levels are low in diabetic patients and reduced further in DR patients,TOS levels are increased in diabetic patients and this is exacerbated in DR patients. | Emrullah Beyazyildiz Ali Bülent ankaya Esra Ergan Mustafa Alparslan Anayol Yasemin zdamar Sevilay Sezer Mehmet Hakan Tirhis Pelin Yilmazbas Faruk ztürk | 2013 | International Journal of Ophthalmology(English edition)2013，6，4： | 4 |
| 2 | Short-term effects of intravitreal triamcinolone acetonide injection on ocular blood flow evaluated with color Doppler ultrasonography显示文摘AIM:To evaluate the changes in ocular blood flow with color Doppler ultrasonography(CDU) after intravitreal triamcinolone acetonide(IVTA) injection.METHODS:A total of 46 patients who underwent IVTA(4 mg/0.1 mL) injection for diabetic macular edema(DME)(n =22), central retinal vein occlusion(CRVO)(n =12) and choroidal neovascular membrane(CNVM)(n =12) were included in the study. Peak systolic velocity(PSV), end diastolic velocity(EDV) and resistivity index(RI) were measured from the ophthalmic artery(OA), the central retinal artery(CRA) and the posterior ciliary artery(PCA)of each patient with CDU before, at the end of the first week and at the end of the first month following IVTA injection.RESULTS:In the DME group, PSV of OA at the first of the first month(mean ±SD)(37.48 ±10.87 cm/s) increased compared to pre-injection value(31.39 ±10.84 cm/s)(P =0.048). There was a statistically significant decrease(P =0.049) in PSV of CRA at the end of the first month(7.97±2.67 cm/s) compared to the pre-injection(9.47±3.37 cm/s).There was not any statistically significant difference onthe other parameters in the DME group. Also, there was not any statistically significant difference on the ocular blood flow values in the CRVO and CNVM groups.CONCLUSION:We observed that 4 mg/0.1 mL IVTA increased PSV of OA and decreased PSV of CRA in DME patients and did not have any effect on ocular blood flow values of CRVO and CNVM patients. | Mustafa Alpaslan Anayol Yasin Toklu Elif Asik Kamberoglu Sabri Raza Hasan Basri Arifoglu Huseyin Simavli Ayse Gul Kocak Altintas Saban Simsek | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 4 |
| 3 | 白内障超声乳化术后前房膜形成的危险因素(英文)显示文摘目的:探讨白内障超声乳化术后前房膜形成的危险因素。方法:对1356例行白内障超声乳化+单片式PMMA人工晶体植入术患者进行前瞻性研究。假性囊膜剥脱综合症,核硬度,瞳孔大小,超声时间,实际超声时间,系统性疾病,术中并发症(囊膜撕裂,悬韧带断裂,后囊破裂伴玻璃体丢失),IOL植入位置和术后并发症(眼内压变化,粘连形成)作为膜形成的危险因素分析。结果:观察到111例患者(8.1%)术后出现伴有膜形成的纤维素性前葡萄膜炎。膜形成平均时间是术后第2d(术后第1~7d),膜存在持续时间平均为5.2d(1~48d)。在膜形成病例中,+4级核病例占45%,而在无膜形成病例中仅为13.5%,差异具有显著统计学意义(P<0.05)。在膜形成组,平均超声时间为2.4min,平均实际超声时间为32.8s,而无膜形成组分别为1.8min和22.1s。这两项参数在膜形成组均明显较长(P<0.05)。在膜形成组中,出现后囊破裂伴玻璃体丢失和IOL睫状沟植入者占33%,而无膜形成组为11%(P<0.05)。其他危险因素在膜形成组和无膜形成组中的比较无统计学意义。在术后第1d和第7d,平均最佳矫正视力(Snellen视力表)在膜形成组分别为0.2和0.4,无膜形成组为0.4和0.6(P<0.05)。但术后3mo,平均最佳矫正视力在膜形成组和无膜形成组中结果相似(分别为0.8和0.9)。结论:晶状体核硬度较高,较长超声时间和实际超声时间,术中后囊破裂是术后前房纤维膜形成的明显相关性危险因素。 | Ayse Gul Kocak Altintas M. Alpaslan Anayol Saban Simsek | 2006 | 国际眼科杂志2006，6，6： | 2 |
| 4 | Comparison of corneal edema caused by cataract surgery with different phaco times in dia- betic and non-diabetic patients 显示文摘 | Altintas AG Yilmaz E Anayol MA | 2006 | Ann Ophthalmol2006，38，1： | 1 |
| 5 | Comparison of Central Corneal Thickness, Thinnest Corneal Thickness, Anterior Chamber Depth, and Simulated Keratometry Using Galilei, Pentacam, and Sirius Devices显示文摘 | Mustafa A. Anayol Emre Güler Ramazan Ya?c Mehmet A. ?ekero?lu Meltem Ylmazo?lu Hakan Trh? Ali E. Kulak Pelin Ylmazba? | 2014 | Cornea2014，，6： | 1 |
| 6 | Evaluation of efficacy of topical povidone-iodine and different types of fluoroquinolones in the sterilization of bacterial flora on the conjunctiva 显示文摘 | Coskun M Altintas AG Anayol MA | 2011 | J Ocul Pharmacol Ther2011，27，6： | 1 |
| 7 | Electron microscopic evaluation of the effect of therapeutic silicone hydrogel lenses on the limbal area显示文摘 | Gurdal C Takmaz T Sargon MF Anayol A Ylmaz E Can I | 2006 | Eye Contact Lens2006，32，3： | 1 |
| 8 | An overlooked effect of systemic anticholinergics:alteration on accommodation amplitude显示文摘AIM: To investigate the effect of oral solifenacin succinate, tolterodine-L-tartarate and oxybutinin hydrochloride(HCl) on accommodation amplitude.·METHODS: Female overactive bladder syndrome(OAB)patients who were planned to use oral anticholinergics,patients that uses solifenacin succinate 5 mg(Group I,n =25), tolterodine-L-tartarate 4 mg(Group II, n =25),and oxybutinin HCl 5 mg b.i.d.(Group III, n =25) and age matched healthy female subjects(Group IV, n =25) were recruited and complete ophthalmological examination and accommodation amplitude assessment were done at baseline and 4wk after initiation of treatment.·RESULTS: The mean age of 100 consecutive female subjects was 51.6 ±5.7(40-60)y and there were no statistically significant difference with regard to the mean age(P =0.107) and baseline accommodation amplitude(P =0.148) between study groups. All treatment groups showed a significant decrease in accommodation amplitude following a 4-week course of anticholinergic treatment(P =0.008 in Group I, P =0.002 in Group II, P =0.001 in Group III), but there was no statistically significant difference in Group IV(P =0.065).·CONCLUSION: A 4-week course of oral anticholinergic treatment have statistically significant effect on accommodation amplitude. Clinicians should avoid both overestimating this result, as this would unnecessarily restrict therapeutic possibilities, and also underestimating it which may lead to drug intolerance. | Mehmet Ali Sekeroglu Emre Hekimoglu Mustafa Alpaslan Anayol Yasemin Tasci Ismail Dolen | 2016 | International Journal of Ophthalmology(English edition)2016，9，5： | 0 |
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