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		题名	作者	年代	出处	被引量
	1	Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer显示文摘AIM: To investigate the role of endothelial nitric oxide synthase-786 T > C promoter polymorphism in the etiology of gastric cancer(GC). METHODS: A total of 150 GC patients and 150 control subjects were included in the study. The information on demographic features was elicited with an informed consent from all the patients and control subjects using a structured questionnaire. Helicobacter pylori(H. pylori) infectivity status was tested in antral biopsies from all the subjects by rapid urease test following the method of Vaira et al. Genomic DNA was isolated from whole blood samples following the salting out method of Lahiri et al. Genotype analysis of the rs2070744 polymorphism was carried out by allele-specific polymerase chain reaction method. The genotypes were determined based on the appearance of bands on an agarose gel stained with ethidium bromide under ultraviolet gel documentation with the help of 100 bp ladder. Odds ratios and corresponding 95%CIs were determined using java stat online software. RESULTS: There was a significant difference in the distribution of C allele(C vs T; P = 0.000, OR = 5.038) in patient group compared to the control subjects exhibiting a fivefold increased risk for GC. When the T/T and C/C genotypes were compared, there was an enhanced GC risk for individuals with C/C genotype(T/T vs C/C; P = 0.000). Among the demographic factors, smoking and alcoholism were the common risk factors in patients compared to the control subjects(P < 0.05). Patients with smoking and alcoholism developed cancer even in heterozygous T/C condition(smoking: P = 0.020 and alcoholism: P = 0.005). Individuals with H. pylori infection showed seven fold increased risk for cancer. All the patients with C/C genotype revealed a significant association between H. pylori infection and GC. Among the patients 2.4% of them revealed familial incidence of GC. No significant difference was noticed between cases and controls with regard to consanguinity(P = 0.473).CONCLUSION: The Present data suggest that eN OS-786 C/C genotype and C allele may be considered as potential risk factors in patients with GC.	Devulapalli Krishnaveni Bhayal Amar Chand Porika Shravan Kumar Malladi Uma Devi Macherla Ramanna Akka Jyothy Nallari Pratibha N Balakrishna Ananthapur Venkateshwari	2015	World Journal of Gastrointestinal Oncology2015，7，7：	2
	2	The genetic bases of uterine fibroids; a review显示文摘	Medikare V Kandukuri L R Ananthapur V et ai	2011	J Reprod Infertil2011，12，3：	1
	3	India' s New Data Protection Legis- lation显示文摘	Raghunath Ananthapur	2011	SCRIPTed2011，8，2：	1
	4	Role of tumor necrosis factor-α -308 G/A promoter polymorphism in gastric cancer显示文摘	Amar Bhayal Devulapalli Krishnaveni Kondadasula RangaRao Varun Bogadi Chowdavaram Suman Akka Jyothy Pratibha Nallari Ananthapur Venkateshwari	2013	Saudi Journal of Gastroenterology2013，，4：	1
	5	Association of estrogen receptor α gene polymorphisms with BMD and their affect on estradiol levels in pre- and postmenopausal women in south Indian population from Andhra Pradesh显示文摘	Yasovanthi Jeedigunta Pulla Reddy Bhoomi Reddy Venkata Karunakar Kolla Anjana Munshi Venkateshwari Ananthapur G. Narasimulu Jyothy Akka	2010	Clinica Chimica Acta2010，，7：	1
	6	A novel chromosomal translocation and heteromorphism in a female with recurrent pregnancy loss-a case study 显示文摘	Ananthapur V Avvari S Cingeetham V	2012	J Assist Reprod Genet2012，29，7：	1
	7	Endothe1in 1 gene as a modifier in dilated cardiomyopathy显示文摘	Matsa LS Sagurthi SR Ananthapur V	2014	Gene2014，548，2：	1
	8	A novel chromosomal translocation and hetemmorphism in a female with recurrent preg- nancy loss a case study显示文摘	Ananthapur V Avvari S Cingeetham V	2012	J Assist Reprod Genet2012，29，7：	1

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