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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Extracardiac Fontan operation for complex cardiac anomalies: seven years' experience 显示文摘 | Amodeo A Galletti L Marianeschi S | 1997 | J Thorac C ardiovasc Surg1997，114，： | 1 |
| 3 | Total cavopulm-onary direct anastomosis : a logical approach in selectedpatients 显示文摘 | CAROTTI A IORIO F S AMODEO A | 1993 | Ann Thorac Surg1993，56，4： | 1 |
| 4 | The role of aquaporins and membrane damage in chilling and hydro gen peroxide induced changes in the hydraulic conductance of maize roots 显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiol2005，137，1： | 1 |
| 5 | The role of aqua- porins and membrane damage in chilling and hydrogen per- oxide induced changes in the hvdraulic conductance of maize roots 显示文摘 | Aroca R Amodeo G Fernandez I S | 2005 | Plant Physio12005，137，： | 1 |
| 6 | Clinical outcome of 193 extracardiac Fontan patients:the first 15 years显示文摘 | GIANNICO S HAMMAD F AMODEO A | 2006 | J Am Coll Cardiol2006，47，10： | 1 |
| 7 | Pefineural dexmedetomidine provides an increased duration of analgesia to a thermal stimulus when compared with a systemic control in a rat sciatic nerve block显示文摘 | Brummett C M Amodeo F S Janda A M | 2010 | Reg Anesth Pain Med2010，35，5： | 1 |
| 8 | Perineural dexmedetomidine added to ropivacaine causes a dose-depend- ent increase in the duration of thermal antinociception in sciatic nerve block in rat显示文摘 | Brummett C M Padda A K Amodeo F S | 2009 | Anesthesiology2009，111，5： | 1 |
| 9 | miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells 显示文摘 | Cascio S D' BAndrea A Ferla R Surmacz E Gulotta E Amodeo V | 2010 | J Cell Physiol2010，224，1： | 1 |
| 10 | The role of aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiol2005，137，1： | 1 |
| 11 | The severity of acute kidney injury predicts progression to chronic kidney disease 显示文摘 | Chawla LS Amdur RL Amodeo S | 2011 | Kidney Int2011，79，12： | 1 |
| 12 | MicroRNA miRNA - 24 promotes cell proliferation by targeting the CDKs inhibitors p27(Kipl) and pl6(INK4a, ) 显示文摘 | Giglio S Cirombella R Amodeo R | 2013 | J Cell Physiol2013，228，10： | 1 |
| 13 | Clinical Outcome of 193 extracardiac Fontan patients: the first 15 years显示文摘 | GIANNICO S HAMMAD F AMODEO A | 2006 | J Am Coll Cardiol2006，47，10： | 1 |
| 14 | The severity of acute kidney injury predicts progression to chronic kidney disease显示文摘 | CHAWLA L S AMDUR R L AMODEO S | 2011 | Kidney Int2011，79，12： | 1 |
| 15 | Extracardiac Fontan operation for complex cardiac anomalies:seven years'experience显示文摘 | Amodeo A Galletti L Marianeschi S | 1997 | J Thorac Cardiovasc Surg1997，114，6： | 1 |
| 16 | The role of Aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiology2005，137，1： | 1 |
| 17 | Non-linear optimal controller for unified power quality conditioners显示文摘 | LEON A E AMODEO S J SOLSONA J A | 2011 | IET Power Electronics2011，4，4： | 1 |
| 18 | The role of aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiol2005，137，： | 1 |
| 19 | The role of aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez I S | 2005 | Plant Physiol2005，137，： | 1 |
| 20 | The severity of acute kidney injury predicts progression to chronic kidney disease显示文摘 | Chawla LS Amdur RL Amodeo S | | 0，，12： | 1 |
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