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| 1 | Roux-en-Y versus BillrothⅠreconstruction after distal gastrectomy for gastric cancer:A meta-analysis显示文摘AIM:To conduct a meta-analysis to compare Rouxen-Y(R-Y) gastrojejunostomy with gastroduodenal Billroth Ⅰ(B-Ⅰ) anastomosis after distal gastrectomy(DG) for gastric cancer.METHODS:A literature search was performed to identify studies comparing R-Y with B-Ⅰ after DG for gastric cancer from January 1990 to November 2012 in Medline,Embase,Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in The Cochrane Library.Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed or random effects model.Operative outcomes such as operation time,intraoperative blood loss and postoperative outcomes such as anastomotic leakage and stricture,bile reflux,remnant gastritis,reflux esophagitis,dumping symptoms,delayed gastric emptying and hospital stay were the main outcomes assessed.Meta-analyses were performed using RevMan 5.0 software(Cochrane library).RESULTS:Four randomized controlled trials(RCTs) and 9 non-randomized observational clinical studies(OCS) involving 478 and 1402 patients respectively were included.Meta-analysis of RCTs revealed that R-Y reconstruction was associated with a reduced bile reflux(OR 0.04,95%CI:0.01,0.14;P < 0.00 001) and remnant gastritis(OR 0.43,95%CI:0.28,0.66;P = 0.0001),however needing a longer operation time(WMD 40.02,95%CI:13.93,66.11;P = 0.003).Metaanalysis of OCS also revealed R-Y reconstruction had a lower incidence of bile reflux(OR 0.21,95%CI:0.08,0.54;P = 0.001),remnant gastritis(OR 0.18,95%CI:0.11,0.29;P < 0.00 001) and reflux esophagitis(OR 0.48,95%CI:0.26,0.89;P = 0.02).However,this reconstruction method was found to be associated with a longer operation time(WMD 31.30,95%CI:12.99,49.60;P = 0.0008).CONCLUSION:This systematic review point towards some clinical advantages that are rendered by R-Y compared to B-Ⅰ reconstruction post DG.However there is a need for further adequately powered,welldesigned RCTs comparing the same. | Jun-Jie Xiong Kiran Altaf Muhammad A Javed Quentin M Nunes Wei Huang Gang Mai Chun-Lu Tan Rajarshi Mukherjee Robert Sutton Wei-Ming Hu Xu-Bao Liu | 2013 | World Journal of Gastroenterology2013，19，7： | 33 |
| 2 | Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis显示文摘AIM: To undertake a meta-analysis on the value of urinary trypsinogen activation peptide (uTAP) in predicting severity of acute pancreatitis on admission. METHODS: Major databases including Medline, Embase, Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in the Cochrane Library were searched to identify all relevant studies from January 1990 to January 2013. Pooled sensitivity, specificity and the diagnostic odds ratios (DORs) with 95%CI were calculated for each study and were compared to other systems/biomarkers if mentioned within the same study. Summary receiver-operating curves were conducted and the area under the curve (AUC) was evaluated. RESULTS: In total, six studies of uTAP with a cut-off value of 35 nmol/L were included in this meta-analysis. Overall, the pooled sensitivity and specificity of uTAP for predicting severity of acute pancreatitis, at time of admission, was 71% and 75%, respectively (AUC = 0.83, DOR = 8.67, 95%CI: 3.70-20.33). When uTAP was compared with plasma C-reactive protein, the pooled sensitivity, specificity, AUC and DOR were 0.64 vs 0.67, 0.77 vs 0.75, 0.82 vs 0.79 and 6.27 vs 6.32, respectively. Similarly, the pooled sensitivity, specificity, AUC and DOR of uTAPvs Acute Physiology and Chronic Health Evaluation Ⅱ within the first 48 h of admission were found to be 0.64 vs 0.69, 0.77 vs 0.61, 0.82 vs 0.73 and 6.27vs 4.61, respectively. CONCLUSION: uTAP has the potential to act as a stratification marker on admission for differentiating disease severity of acute pancreatitis. | Wei Huang Kiran Altaf Tao Jin Jun-Jie Xiong Li Wen Muhammad A Javed Marianne Johnstone Ping Xue Christopher M Halloran Qing Xia | 2013 | World Journal of Gastroenterology2013，19，28： | 7 |
| 3 | Degradation of malathion by Pseudomonas during activated sludge treatment system using principal component analysis (PCA)显示文摘Popular descriptive multivariate statistical method currently employed is the principal component analyses (PCA) method. PCA is used to develop linear combinations that successively maximize the total variance of a sample where th ere is no known group structure. This study aimed at demonstrating the performan ce evaluation of pilot activated sludge treatment system by inoculating a strain of Pseudomonas capable of degrading malathion which was isolated by enrichment technique. An intensive analytical program was followed for evaluating the effic iency of biosimulator by maintaining the dissolved oxygen (DO) concentration at 4.0 mg/L. Analyses by high performance liquid chromatographic technique revealed that 90% of malathion removal was achieved within 29 h of treatment whereas COD got reduced considerably during the treatment process and mean removal efficien cy was found to be 78%. The mean pH values increased gradually during the treatm ent process ranging from 7.36—8.54. Similarly the mean ammonia-nitrogen (NH3-N) values were found to be fluctuating between 19.425—28.488 mg/L, mean nitrite-n itrogen (NO3-N) ranging between 1.301—2.940 mg/L and mean nitrate-nitrogen (NO3 -N) ranging between 0.0071—0.0711 mg/L. The study revealed that inoculation of bacterial culture under laboratory conditions could be used in bioremediation of environmental pollution caused by xenobiotics. The PCA analyses showed that pH, COD, organic load and total malathion concentration were highly correlated and emerged as the variables controlling the first component, whereas dissolved oxyg en, NO3-N and NH3-N governed the second component. The third component repeated the trend exhibited by the first two components. | Hashmi Imran Khan M Altaf Kim Jong-Guk | 2006 | Journal of Environmental Sciences2006，18，4： | 3 |
| 4 | Production of L(+)lactic acid by Lactobacillus amylophilus GV6 in semi-solid state fermentation using wheat bran显示文摘 | NAVAEENA B J ALTAF M BHADRIAH K | 2004 | Food Technol Biotechnol2004，42，： | 1 |
| 5 | Single step fermentation of starch to L (+) lactic acid by Lactobacillus amylophilus GV6 in SSF using inexpensive nitrogen sources to replace peptone and yeast extract-Optimization by RSM显示文摘 | Altaf M Naveena B J Venkateshwar M | 2006 | Process Biochemistry2006，41，2： | 1 |
| 6 | Curcumin,a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase,represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin显示文摘 | Balasubramanyam K Varier R A Altaf M | 2004 | J Biol Chem2004，279，51： | 1 |
| 7 | Polyisoprenylated benzophenone,garcinol,a natural histone acetyltransferase inhibitor,represses chromatin transcription and alters global gene expression显示文摘 | Balasubramanyam K Altaf M Varier R A | 2004 | J Biol Chem2004，279，33： | 1 |
| 8 | Household demand for improved solid waste management:a case study of Gujranwala,Pakistan显示文摘 | Altaf M A Deshazo J R | 1996 | World Development1996，，5： | 1 |
| 9 | Laparoscopic accessory splenectomy:the value of perioperative localization studies显示文摘 | Altaf AM Sawatzky M Ellsmere J | 2009 | Surg Endosc2009，23，12： | 1 |
| 10 | Selection of medium components by Plackett -Burman design for production of L ( + ) lactic acid by Lactobacillus amylophilus GV6 in SSF using wheat bran 显示文摘 | NAVEENA B J ALTAF M D BHADRIAH K | 2005 | Bioresource Technology2005，96，： | 1 |
| 11 | Amylolytic bac- terial lactic acid fermentation : A review显示文摘 | Reddy G Altaf M Naveena B J | 2008 | Biotechnolo- gy Advances2008，26，1： | 1 |
| 12 | Host adaptation and host–parasite co-evolution in Cryptosporidium : implications for taxonomy and public health显示文摘 | Lihua Xiao Irshad M Sulaiman Una M Ryan Ling Zhou Edward R Atwill Monica L Tischler Xichen Zhang Ronald Fayer Altaf A Lal | 2002 | International Journal for Parasitology2002，，14： | 1 |
| 13 | Polysoprenylated Benzophenone,garcinol,a natural histone acetyltransferase inhibitor,represses chromatin transcription and alters global gene expression 显示文摘 | Balasubramanyam K Altaf M Varier RA | 2004 | J Biol Chem2004，279，33： | 1 |
| 14 | Direct fermentation of starch to 1 (+) lactic acid in SSF by Lactobacillus amylophilus GV6 using wheat bran as support and substrate: medium optimization using RSM显示文摘 | Naveena B J Altaf M Bhadrayya K | 2005 | Process Biochemistry2005，40，2： | 1 |
| 15 | 查看详情显示文摘 | Hussain M Hanif M Altaf M | | 0，，01： | 1 |
| 16 | Polyiso-prenylated benzophenone,garcinol,a natural histone acetyltransferase inhibitor,represses chromatin transcription and alters global gene expression 显示文摘 | Balasubramanyam K Altaf M Varier RA | 2004 | J Biol Chem2004，279，33： | 1 |
| 17 | What is the evidence for the management of urethral amyloidosis? A systematic re- viewoitheliterature显示文摘 | ALTAF M KATE DL MALEE F | 2011 | BJU Int2011，109，12： | 1 |
| 18 | Use of inexpensive nirogen sources and starch for L-lactic acid production in anaerobic submerged fermentation显示文摘 | Altaf M Naveena B J Reddy G | 2007 | Bioresource Technology2007，98，： | 1 |
| 19 | Amylolytic bacterial lactic acid fermentation- A review显示文摘 | Reddy G Altaf M Naveena B J | 2008 | Bioteehnology Advances2008，26，1： | 1 |
| 20 | Direct fermentation of starch to L(+) lactic acid in SSF by Lactobacillus amylophilus GV6 using wheat bran as support and substrate: medium optimization using RSM显示文摘 | Naveena B J Altaf M Bhadrayya K | 2005 | Process Biochemistry2005，40，2： | 1 |
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