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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis显示文摘BACKGROUND Rotator cuff pathology is a very common source of shoulder pain.Similarly,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar symptoms.Surgical management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of GHOA.AIM To evaluate if a relationship exists between outcomes of RCR in the setting of GHOA.METHODS This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between 2010-2017.Patients were stratified based on rotator cuff tear size and glenohumeral osteoarthritis severity.Cohorts were paired 1:1 with patients without glenohumeral osteoarthritis.Patients included had a minimum two year follow-up.Rate of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were collected.RESULTS A total of 142 patients were included.The number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without GHOA.Following rotator cuff repair,both groups showed favorable patientreported outcomes.CONCLUSION Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis. | Ian S Hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman | 2022 | World Journal of Orthopedics2022，13，7： | 2 |
| 3 | Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer显示文摘AIM: To evaluate the M1 and M2 monocyte phenotype in patients with non-small cell lung cancer(NSCLC) compared to controls. Also, to examine the expression of Th1 and Th2 cytokines in plasma of NSCLC vs controls. METHODS: Freshly prepared peripheral blood mononuclear cells samples were obtained from patients with NSCLC(lung adenocarcinoma and squamous cell lung carcinoma) and from non-cancer controls. Flow cytometry was performed to investigate M1 and M2 phenotypes in peripheral monocytes(classical monocytes CD14+, CD45+ and CD16-) using conventional surface markers. Th1 and Th2 cytokine production was alsoanalysed in the plasma using cytometric bead array technique. RESULTS: There were no significant difference in expression of M1(HLA-DR) and/or M2 markers(CD163 and CD36) markers on classical monocytes in patients with NSCLC compared to non-cancer controls. Expression of CD11 b, CD11 c, CD71 and CD44 was also shown to be similar in patients with NSCLC compared to noncancer controls. Th1 and Th2 cytokines [interleukin(IL)-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12(p70), tumor necrosis factor(TNF)-α, TNF-β, and interferon-γ] analysis revealed no significant difference between patients with NSCLC and non-cancer controls. CONCLUSION: This study shows no alteration in peripheral monocyte phenotype in circulating classical monocytes in patients with NSCLC compared to noncancer controls. No difference in Th1 and Th2 cytokine levels were noted in the plasma of these patients. | Saleh A Almatroodi Christine F Mc Donald Allison L Collins I an A Darby Dodie S Pouniotis | 2014 | World Journal of Clinical Oncology2014，5，5： | 2 |
| 4 | Knee osteoarthritis:Therapeutic alternatives in primary care显示文摘AIM To discusses pharmacological and non-pharmacological therapeutic alternatives for managing knee osteoarthritis in primary care by primary health care nurse practitioners.METHODS A case example is presented, the evidence-based guideline recommendations of the Osteoarthritis Research Society International and the American Academy of Orthopaedic Surgeons are reviewed, and a plan of care is developed.RESULTS Osteoarthritis is the most common form of arthritis seen in primary care, and it is a major public health issue because the aging population and widespread obesity have drastically increased incidence. Osteoarthritis is clinically associated with escalating chronic pain, physical disability, and decreased quality of life. Early diagnosis of mild osteoarthritis in relatively young patients presents an opportunity for primary health care providers to manage pain, increase quality of life, and decrease risk of disability. CONCLUSION Primary health care providers can implement these recommendations in their own practices to provide care to patients with knee osteoarthritis based on current best evidence. | Allison L Evaniew Nathan Evaniew | 2017 | World Journal of Orthopedics2017，8，2： | 2 |
| 5 | The development of the self in the era of the internet and role-playing fantasy games显示文摘 | Allison SE von Wahlde L Shockley T | 2006 | Am J Psychiatry2006，163，3： | 1 |
| 6 | A novel hepatitis B virus variant in the sera of immunized children显示文摘 | Karthigesu V D Allison L M C Fortuin M | 1994 | J Gen Virol1994，75，： | 1 |
| 7 | Developmental and aging changes in somatosensory,auditory and visual evoked potentials显示文摘 | Allison T Hume A L Wood C C | 1984 | Electroencephalogr Clin Neurophysiol1984，58，1： | 1 |
| 8 | Changes in enzymeactivities and soil microbial community composition along carbonand nutrient gradients at the Franz Josef chronosequence,NewZealand显示文摘 | ALLISON V J CONDRON L M PELTZER D A | 2007 | Soil Biological and Biochemistry2007，39，7： | 1 |
| 9 | Antipsychotic- induced weight gain:a comprehensive research synthesis显示文摘 | ALLISON D B MENTORE J L HEO M | 1999 | Am J Psychiatry1999，156，11： | 1 |
| 10 | Adaptation of tick-borne encephalitis virus to BHK-21 ceils results in the for- mation of multiple heparan sulfate binding sites in the envelope protein and attenuation in Vivo 显示文摘 | MANDL C W KROSCHEWSKI H ALLISON S L | 2001 | J Virol2001，75，： | 1 |
| 11 | Milestones in chloroplast genetic engineering:an environmentally friendly era in biotechnology显示文摘 | DANIELL H KHAN M S ALLISON L | 2002 | Trends Plant Sci2002，7，2： | 1 |
| 12 | Heart mitochondria contain functional ATP-dependent K^+ channels 显示文摘 | Zsombor L James A S Allison W M | 2003 | J Mo Cell Cardiol2003，35，11： | 1 |
| 13 | Milestones in chloroplast genetic engineering:an environmentally friendly era in biotechnology显示文摘 | Daniell H Khan M S Allison L | | 0，，： | 1 |
| 14 | Preparation of Cr-doped Y3Al5O12 phosphors by heterogeneous precipitation methods and their luminescent properties显示文摘 | MATSUBARA I PARANTHAMAN M ALLISON S W CATES M R BESHEARS D L HOLCOMB D E | 2000 | Materials Research Bulletin2000，35，2： | 1 |
| 15 | Behavioural responses of piglets to castration : the effect of piglet age 显示文摘 | Allison A T Daniel M W Martin L | 2001 | AppliedAnimal Behaviour Science2001，73，1： | 1 |
| 16 | Patterns in nutrient availability and plant diversity of temperate north America wetlands显示文摘 | BEDFORD L B WALBRIDGE M R ALLISON A | 1999 | Ecology1999，80，7： | 1 |
| 17 | Equivalent wind-erosion protection fi'om selected crop residues显示文摘 | Lyles L Allison B E | 1981 | Transactions of the ASAE1981，24，： | 1 |
| 18 | Patterns in nutrient availability and plant diversity of temperate North American wetlands显示文摘 | Barbara L B Mark RW Allison A | 1999 | Ecology1999，7，： | 1 |
| 19 | Marine waterjet propulsion显示文摘 | ALLISON J L | 1993 | SNAME Transactions1993，101，： | 1 |
| 20 | Adoption of cloud computing technologies in supply Chains显示文摘 | Cegielski C G Allison L J Wu Y | 2012 | The International Journal of Logistics Management2012，23，2： | 1 |
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