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| 1 | HLA is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells 显示文摘 | King A Allan DS Bowen M | 2000 | Eur J Immunol2000，30，6： | 1 |
| 2 | Analyses of expressed sequence tags from apple显示文摘 | NEWCOMB R D CROWHURST R N GLEAVE A P RIKKERINK E H A ALLAN A C BEUNING L L BOWEN J H GERA E JAMIESON K R JANSSEN B J LAING W A MCARTNEY S NAIN B ROSS G S SNOWDEN K C SOULEYRE E J F WALTON E F YAUK Y K | 2006 | Plant Physiology2006，141，： | 1 |
| 3 | Differential expression within the LOX gene family in ripening kiwifruit显示文摘 | ZHANG B CHEN K S BOWEN J ALLAN A ESPLEY R KARUNAIRETNAM S FERGUSON I | 2006 | Journal of Experimental Botany2006，57，14： | 1 |
| 4 | Differential expression within the LOX gene family in ripening kiwifruit显示文摘 | ZHANG B CHEN K S BOWEN J ALLAN A ESPLEY R KARUNA1RETNAM S FERGUSON I | 2006 | Journal of Experimental Botany2006，57，： | 1 |
| 5 | Analyses of expressed sequence tags from apple显示文摘 | NEWCOMB R D CROWHURST R N CLEAVE A P RIKKERINK E H A ALLAN A C BEUNING L L BOWEN J H GERA E JAMIESON K R JANSSEN B J LAING W A | 2006 | Plant Physiology2006，141，1： | 1 |
| 6 | Differential expression within the LOX gene family in ripening kiwifruit显示文摘 | ZHANG B CHEN K S BOWEN J ALLAN A ESPLEY R KARUNAIRETNAM S FERGUSON I | 2006 | Journal of experimental botany2006，57，14： | 1 |
| 7 | HLA-E is expressed on trophoblast and interacts with CD94 /NKG2 receptors on decidual NK cells显示文摘 | King A Allan DS Bowen M | | 0，，06： | 1 |
| 8 | HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells 显示文摘 | King A Allan D S Bowen M | 2000 | Eur J Immunol2000，30，6： | 1 |
| 9 | HLA-E is expressed on trophoblast and interact with CD94/CDNKG2 receptors on decidual NK cells显示文摘 | King A Allan D S Bowen M | 2000 | Eur J Immunol2000，30，： | 1 |
| 10 | HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells显示文摘 | Allan DS Bowen M | 2000 | Eur J Immunol2000，30，6： | 1 |
| 11 | HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells 显示文摘 | Allan DS Bowen M | 2000 | Eur J Immunol2000，30，6： | 1 |
| 12 | HLA-E is expressed on trophoblast and interact with CD94/CDNKG2 receptors on decidual NK cells显示文摘 | King A Allan DS Bowen MP | 2000 | Eur J Immonol2000，30，5： | 1 |
| 13 | HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells显示文摘 | King A Allan DS Bowen M | 2000 | Eur J Immunol2000，30，： | 1 |
| 14 | Analysis of expressed sequence tags from Actinidia:applications of across species EST database for gene discovery in the areas of flavor,health,color and ripening显示文摘 | CROWHURST R N GLEAVE A P MACRAE E A MPOMAH-DWAMENA C A ATKINSON R G BEUNING L L BULLEY S M CHAGNE D MARSH K B MATICH A J MONTEFIORI M NEWCOMB R D SCHAFFER R J USADEL B ALLAN A C BOLDINGH H L BOWEN J H DAVY M W ECKLOFF R FER-GUSON A R FRASER L G GERA E HELLENS R P JANSSENB J KLAGES K LO K R NAIN B MCNEILAGE M A DI-ARMID R M M RASSAM M RICHARDSON A C RIKKERINK EH A Ross G S SCHRODER R SNOWDEN K C SOULEYRE E JF TEMPLETON M D WALTON E F WANG D WANG M Y WANG Y Y WOOD M WU R M YAUK Y K LIANG W A | 2008 | BMC Genomics2008，9，351： | 1 |
| 15 | PLGA nanodepots co-encapsulating prostratin and anti-CD25 enhance primary natural killer cell antiviral and antitumor function显示文摘Natural killer(NK)cells are attractive effector cells of the innate immune system against human immunodeficiency virus(HIV)and cancer.However,NK cell therapies are limited by the fact that target cells evade NK cells,for example,in latent reservoirs(in HIV)or through upregulation of inhibitory signals(in cancer).To address this limitation,we describe a biodegradable nanoparticlebased“priming”approach to enhance the cytotoxic efficacy of peripheral blood mononuclear cell-derived NK cells.We present poly(lactic-co-glycolic acid)(PLGA)nanodepots(NDs)that co-encapsulate prostratin,a latency-reversing agent,and anti-CD25(aCD25),a cell surface binding antibody,to enhance primary NK cell function against HIV and cancer.We utilize a nanoemulsion synthesis scheme to encapsulate both prostratin and aCD25 within the PLGA NDs(termed Pro-aCD25-NDs).Physicochemical characterization studies of the NDs demonstrated that our synthesis scheme resulted in stable and monodisperse Pro-aCD25-NDs.The NDs successfully released both active prostratin and anti-CD25,and with controllable release kinetics.When Pro-aCD25-NDs were administered in an in vitro model of latent HIV and acute T cell leukemia using J-Lat 10.6 cells,the NDs were observed to prime J-Lat cells resulting in significantly increased NK cell-mediated cytotoxicity compared to free prostratin plus anti-CD25,and other controls.These findings demonstrate the feasibility of using our Pro-aCD25-NDs to prime target cells for enhancing the cytotoxicity of NK cells as antiviral or antitumor agents. | Elizabeth E.Sweeney Preethi B.Balakrishnan Allison B.Powell Allan Bowen Indra Sarabia Rachel A.Burga R.Brad Jones Alberto Bosque C.Russell Y.Cruz Rohan Fernandes | 2020 | Nano Research2020，13，3： | 0 |
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