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11篇 您的检索式:作者名="Alias Z"
    题名 作者 年代 出处 被引量
1Amyloid β and free heme:bloody new insights into the pathogenesis of Alzheimer's disease显示文摘The cerebral formation of Amyloid β(Aβ) is a critical pathological feature of Alzheimer's disease(AD).An accumulation of this peptide as senile plaques(SP) was already reported by Alois Alzheimer,the discoverer of the disease.Yet the exact contribution of Aβ to AD development remains elusive.Moreover,while extensive cerebral Aβ formation leads to fibril formation in many species,AD-like symptoms apparently depend on the highly conserved N-terminal residues R5,Y10 and H13.The amino acids were also shown to lead to the formation of Aβ-heme complexes,which exhibit peroxidase activity in the presence of H_2O_2.Taking together these observations we propose that the formation and enzymatic activity of the named complexes may represent an essential aspect of AD pathology.Furthermore,Aβ is also known to lead to cerebral micro-vessel destruction(CAA) as well as to hemolytic events.Thus we suggest that the Aβ-derived cerebral accumulation of blood-derived free heme represents a likely precondition for the subsequent formation of Aβ-heme complexes.Jorg Flemmig Marcel Zámocky A Alia 2018Neural Regeneration Research2018,13,7:1
2IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer显示文摘ALIA Z SANDHU M S LUBEN R N 2006Human Molecular Genetics2006,15,1:1
3Isolation of palm oil-utilising,polyhydroxyalkanoate (PHA)-producing bacteria by an enrichment technique显示文摘ALIAS Z TAN I K 2005Bioresour Technol2005,96,11:1
4Adult Drosophila melanogaster glutathi- one S-transferases: Effects of acute treatment with methyl parathion 显示文摘Alias Z Clark A G 2010Pesticide Biochemistry and Physiology2010,98,:1
5Synthesis and characterization of Li4Ti5O12显示文摘ALIAS N A KUFIAN M Z TEO L P 2009Journal of Alloys and Compounds2009,486,12:1
6Morphology and thermo-mechanical properties of compatibilized polyimide-silica nanocomposities 显示文摘AL-KANDARY SH ALIA AM AHMAD Z 2005Journal ofApplied Polymer Science2005,98,6:1
7Shape recovery and viewpoint planning for reverse engineering显示文摘DAN Z ALIA 2005The International Journal of Advanced Manufacturing Technology2005,26,:1
8显示文摘Alias N A Kufian M Z Teo L P 2009Journal of Alloys and Compounds2009,486,:1
9Morphology and thermo-meehanical properties of compatibilized polyirnide-silica nanocomposites 显示文摘AL-KANDARY S H ALIA A M AI-IMAD Z 2005JAppl Polym Sci2005,98,:1
10Discrimination and identification of geographical origin virgin olive oil by an e -nose based on MOS sensors and pattern recognition techniques 显示文摘HADDI Z AMARI A ALIA O 2011Procedia Eng2011,25,:1
11Influence of the entomopathogenic fungus Isaria fumosorosea onAxinoscymnus cardilobus (Coleoptera: Cocinellidae) under laboratory condition显示文摘Zhou F Alia S Huang Z 2010Biocontrol Science and Technology2010,20,7:1
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