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| 1 | Recurrent aggressive mesenteric desmoid tumor successfully treated with sorafenib: A case report and literature review显示文摘BACKGROUND Desmoid tumors(DT) are locally advanced but histologically benign monoclonal neoplasms that can occur from any musculoaponeurotic structure. The aim of this report is to analyze a rare clinical case of an aggressive intra-abdominal DT successfully treated with sorafenib.CASE SUMMARY A 36-year-old man presented with increasing colicky abdominal pain and a selfpalpable mass in his left abdomen. Fourteen years earlier he was diagnosed with a large intra-abdominal tumor, which adhered to the left colonic flexure, part of the major gastric curvature and the spleen. Subsequent exploratory laparotomy revealed a voluminous mass in the epigastrium, arising from the posterior surface of the stomach and invading the superior mesenteric vessels, transverse mesocolon and the small bowel mesentery. As the tumor was unresectable, a jejunojejunal bypass was performed. Traditional therapeutic interventions proved insufficient, and the patient was started on sorafenib with a subsequent fulldisease response.CONCLUSIONDT's pathogenesis has been associated with mutations in the adenomatous polyposis coli(APC) gene or beta-catenin gene CTNNB1, sex steroids or previous surgical trauma. Local treatment modalities, such as surgery or radiotherapy, are implemented in aggressively progressing or symptomatic patients. Sorafenib is a hopeful therapeutic option against DTs, while several pharmacological agents have been successfully used. | Aikaterini Mastoraki Dimitrios Schizas Chrysovalantis Vergadis Leon Naar Alexios Strimpakos Michail G Vailas Natasha Hasemaki George Agrogiannis Theodore Liakakos Nikolaos Arkadopoulos | 2019 | World Journal of Clinical Oncology2019，10，4： | 4 |
| 2 | A Modular Approach to Generating Fuzzy Rules with Reduced Attributes for the Monitoring of Complex Systems显示文摘 | Qiang S Alexios C | 2000 | Engineering Application of Artificial Intelligence2000，13，3： | 1 |
| 3 | Electrowetting properties of micro/nanostructures black silicon 显示文摘 | Marios B Vassilia Z Alexios P | 2010 | J Am Chem Soc2010，26，13： | 1 |
| 4 | Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs:Three case reports and a literature review显示文摘BACKGROUND Alopecia areata(AA)is an inflammatory disease with autoimmune,environmental,and inherited components directed at the hair follicle,either limited to patchy hair loss over the scalp(Focalis,AF),total loss of scalp hair(Totalis,AT),or total loss of both scalp and body hair(Universalis,AU).Despite multiple treatment modalities,no therapy exists.Vitamin D deficiency in patients with AA/AT/AF influences disease severity and duration,inversely correlating with inflammation histologically.CASE SUMMARY Three girls presented with AT(P1),AU(P2),and AF(P3)at the ages of 1,5,and 5 years,respectively.For P1-P2,all available treatments implemented for 2 years had failed.We started an initial 6-mo repletion with oral cholecalciferol 2000/4000 IU/d,with no apparent effect.Then we attempted immunomodulation using oral calcitriol and its analog paricalcitol.On calcitriol,0.5 mcg/d P1 regrew hair within 6 mo.After 4 years,a relapse with loss of eyebrow hair was resolved after doubling the calcitriol dose to 0.5 mcg×2/d;the results have been maintained for 6 years to date.On calcitriol,0.25 mcg×3/d P2 led to the development of asymptomatic hypercalcemia-hypercalciuria,which was immediately resolved by switching to paricalcitol 2 mcg×3/d;mild tolerable hypercalciuria was maintained.Hair regrowth was observed at 6 mo,stabilizing only as fur at 12 mo.AF in P3 was resolved completely within 3 mo on a daily high dose(8000 IU)of cholecalciferol.CONCLUSION Vitamin D may have immunomodulating therapeutic impact on AT/AU/AF,which needs to be explored with further pilot clinical trials. | Dimitrios T Papadimitriou Christina Bothou Eleni Dermitzaki Alexios Alexopoulos George Mastorakos | 2021 | World Journal of Clinical Pediatrics2021，10，6： | 1 |
| 5 | Arnodular approach to generating fuzzy rules with redfaced attributes for the monitoring of complex systems显示文摘 | Qiang S Alexios C | 2000 | Engineering Application of Artificial Intelligence2000，13，3： | 1 |
| 6 | Energy efficiency of manufacturing processes: A Critical Review 显示文摘 | Apostolos F Alexios P Georgios P | 2013 | Procedia CIRP ($2212-8271)2013，7，5： | 1 |
| 7 | The value of serial cervical length measurements for the prediction of threatened preterm labour显示文摘 | Alexandros S Alexios K Stefania P | | 0，，01： | 1 |
| 8 | Characterization and expression analysis of FRUIRFULL-and SHTTERPROOFlike genes from peach (prunus persica) and their role in splitpit formation 显示文摘 | Eleni T Alexios N P Athanasios S T | 2007 | Tree Physiology2007，27，： | 1 |
| 9 | Molecular path- ways and genetic factors in the pathogenesis of laryngopharyn geal reflux显示文摘 | Alexios S Alexander D Katerina D | 2009 | Eur Arch Otorhinolaryngol2009，266，： | 1 |
| 10 | A rough-fuzzy approach for generating classification rules显示文摘 | Qiang Shen Alexios chouchoulas | 2002 | Pattern Recogonition2002，35，： | 1 |
| 11 | A computer-vision system and methodology for the analysis of fish behavior显示文摘 | Vassilis M. Papadakis Ioannis E. Papadakis Fani Lamprianidou Alexios Glaropoulos Maroudio Kentouri | 2011 | Aquacultural Engineering2011，，： | 1 |
| 12 | Characterization and expression analysis of AGAMOUS-like, SEEDSTICKlike, and SEPALLATA-like MADS-box genes in peach(Prunus persica) fruit显示文摘 | Tani E Alexios NP Emmanouil F | 2009 | Plant Physiol Biochem2009，47，： | 1 |
| 13 | A rough- fuzzy approach for generating classification rules显示文摘 | Qiang Shen Alexios chouchoulas | 2002 | Pattern Recogonition2002，，35： | 1 |
| 14 | 查看详情显示文摘 | Evie L.P Marios B Vassilia Z Aleka M. Alexios P. Emmanuel S. Costas F | | 0，，07： | 1 |
| 15 | Nanoseale zero- valent iron supported on mesoporous silica: characterization and reactivity for Cr(VI) removal from aqueous solution显示文摘 | Eleni Petala Konstantinos Dimos Alexios Douvalis | 2013 | Journal of Hazardous Materials2013，261，2013： | 1 |
| 16 | Amodular Approach to Gen-Erating Fuzzy Rules with Reduced Attributes for the Monitoring of Complex Systems显示文摘 | Qiang Sh Alexios Ch | 2000 | Engineering Application of Artificial Intelligence2000，13，3： | 1 |
| 17 | Phase-transfer catalyzed synthesis of flavonoid glycosides 显示文摘 | Costas D Alexios L Fran T | 1990 | Carbo- hydr Res1990，207，： | 1 |
| 18 | Transarterial Chemoembolization of Unresectable Hepatocellular Carcinoma with Drug Eluting Beads: Results of an Open-Label Study of 62 Patients显示文摘 | Katerina Malagari Katerina Chatzimichael Efthymia Alexopoulou Alexios Kelekis Brenda Hall Spyridon Dourakis Spyridon Delis Athanasios Gouliamos Dimitrios Kelekis | 2008 | CardioVascular and Interventional Radiology2008，，2： | 1 |
| 19 | Evaluation of gasoline-ethanol-water ternary mixtures used as a fuel for an Otto engine显示文摘 | Kyriakides Alexios Dimas Vasilis Lymperopoulou Eleni | 2013 | Fuel2013，108，： | 1 |
| 20 | Rough Set-Aided Keyword Reduction For Text Categorization 显示文摘 | Alexios Chouchoulas & Qiang Shen | 2001 | Application Artificial intelligence2001，8，： | 1 |
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