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| 1 | Large gangliocytic paraganglioma of the duodenum:A rare entity显示文摘Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. | Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean | 2015 | World Journal of Gastrointestinal Surgery2015，7，8： | 2 |
| 2 | Performance of cold-preserved rat liver Microorgans as the biological component of a simplified prototype model of bioartificial liver显示文摘AIM To develop a simplified bioartificial liver(BAL) device prototype, suitable to use freshly and preserved liver Microorgans(LMOs) as biological component. METHODS The system consists of 140 capillary fibers through which goat blood is pumped. The evolution of hema-tocrit, plasma and extra-fiber fluid osmolality was evaluated without any biological component, to characterize the prototype. LMOs were cut and cold stored 48 h in BG35 and Via Span~? solutions. Fresh LMOs were used as controls. After preservation, LMOs were loaded into the BAL and an ammonia overload was added. To assess LMOs viability and functionality, samples were taken to determine lactate dehydrogenase(LDH) release and ammonia detoxification capacity. RESULTS The concentrations of ammonia and glucose, and the fluids osmolalities were matched after the first hour of perfusion, showing a proper exchange between blood and the biological compartment in the minibioreactor. After 120 min of perfusion, LMOs cold preserved in BG35 and Via Span~? were able to detoxify 52.9% ± 6.5% and 53.6% ± 6.0%, respectively, of the initial ammonia overload. No significant differences were found with Controls(49.3% ± 8.8%, P < 0.05). LDH release was 6.0% ± 2.3% for control LMOs, and 6.2% ± 1.7% and 14.3% ± 1.1% for BG35 and Via Span~? cold preserved LMOs, respectively(n = 6, P < 0.05). CONCLUSION This prototype relied on a simple design and excellent performance. It’s a practical tool to evaluate the detoxification ability of LMOs subjected to different preservation protocols. | María Dolores Pizarro María Gabriela Mediavilla Alejandra Beatriz Quintana ángel Luis Scandizzi Joaquín Valentín Rodriguez María Eugenia Mamprin | 2016 | World Journal of Hepatology2016，8，33： | 1 |
| 3 | Evolution of Bacillus thuringiensis Cry toxins insecticidal activity显示文摘 | Alejandra Bravo Isabel Gómez Helena Porta Blanca Ines García‐Gómez Claudia Rodriguez‐Almazan Liliana Pardo Mario Soberón | 2012 | Microbial Biotechnology2012，，1： | 1 |
| 4 | Garlic and Onion Attenuates Vascular Inflammation and Oxidative Stress in Fructose-Fed Rats显示文摘 | Marcela Alejandra Vazquez-Prieto Cecilia Rodriguez Lanzi Carina Lembo Claudio Rómulo Galmarini Roberto Miguel Miatello C. S. Johnston | 2011 | Journal of Nutrition and Metabolism2011，，： | 1 |
| 5 | Wheat genotypic variability in grain yield and carbon isotope discrimination under Mediterranean conditions assessed by spectral reflectance显示文摘A collection of 368 advanced lines and cultivars of spring wheat(Triticum aestivum L.) from Chile, Uruguay, and CIMMYT(Centro Internacional de Mejoramiento de Maíz y Trigo), with good agronomic characteristics were evaluated under the Mediterranean conditions of central Chile. Three different water regimes were assayed: severe water stress(SWS, rain fed), mild water stress(MWS; one irrigation around booting), and full irrigation(FI; four irrigations: at tillering,flag leaf appearance, heading, and middle grain filling). Traits evaluated were grain yield(GY), agronomical yield components,days from sowing to heading, carbon isotope discrimination(D13C) in kernels, and canopy spectral reflectance. Correlation analyses were performed for 70 spectral reflectance indices(SRI) and the other traits evaluated in the three trials. GY and D13C were the traits best correlated with SRI, particularly when these indices were measured during grain filling. However,only GY could be predicted using a single regression, with ResearchNormalized Difference Moisture Index(NDMI2: 2,200; 1,100)having the best fit to the data for the three trials. For D13C, only individual regressions could be forecast under FI(r2: 0.25–0.37)and MWS(r2: 0.45–0.59) but not under SWS(r2: 0.03–0.09).NIR‐based SRI proved to be better predictors than those that combine visible and NIR wavelengths. | Gustavo A. Lobos Iván Matus Alejandra Rodriguez Sebastián Romero-Bravo José Luis Araus Alejandro del Pozo | 2014 | Journal of Integrative Plant Biology2014，56，5： | 1 |
| 6 | Effect of Ambient Temperature and Humidity Conditions on the Efficacy of Organic Treatments against Varroa destructor in Different Climatic Zones of Chile显示文摘 | Aldea Patricia Rodriguez Rafael Olivares Alejandra Farffin Macarena Riveros Daniel Nfifiez Fanny Trivelli Luz | 2013 | Journal of Agricultural Science and Technology(A)2013，3，6： | 0 |
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