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| 1 | Validation of modified albumin-bilirubin-TNM score as a prognostic model to evaluate patients with hepatocellular carcinoma显示文摘BACKGROUND An ideal staging system for hepatocellular carcinoma(HCC)should rely on the hepatic reserve function and tumor burden.With the improvement in diagnostic and treatment strategies for HCC,in addition to recent treatment of viral hepatitis,finding a suitable assessment tool for hepatic reserve has become mandatory.AIM To validate a recently proposed modified albumin-bilirubin-TNM(mALBI-T)grade as a prognostic model for patients with HCC in Egypt.METHODS For patients diagnosed with HCC,Child-Turcotte-Pugh(CTP)score,Barcelona Clinic Liver Cancer(BCLC)stage,albumin-bilirubin(ALBI),plateltetalbumin– bilirubin(PALBI),ALBI-based BCLC,ALBI-T and mALBI-T grades were estimated.Patients were followed from time of diagnosis to date of death or date of data collection if they remained alive.Overall survival and received treatments were determined.Survival data were analyzed.RESULTS A total of 1910 patients were included(mean age,57 years;1575 males).At presentation,50.6%had CTP A,36.1%had CTP B and 13.4%had CTP C;12%had ALBI grade 1,62.3%had ALBI grade 2 and 24.7%had ALBI grade 3.Overall median survival was 13 mo;survival was better in patients with ALBI 1 than in those with ALBI 2 and 3(28.6 vs 14 and 5.8 mo,respectively,P<0.001).Patients with ALBI-T grades 0 and 1 had better survival than those with ALBI-T grades 2,3,4 and 5(P<0.001).The modified ALBI-T showed better stratification and significant improvement in prediction of survival.CONCLUSION ALBI-T grade is a superior prognostic tool that selects patients with HCC who have better liver reservoir and tumor stage.mALBI-T is a better prognostic model in patients with HCC. | Omar Elshaarawy Alzhraa Alkhatib Mostafa Elhelbawy Asmaa Gomaa Naglaa Allam Ayman Alsebaey Eman Rewisha Imam Waked | 2019 | World Journal of Hepatology2019，11，6： | 7 |
| 2 | Endoscopic ultrasonography-guided diagnosis of subepithelial tumors显示文摘 | Alkhatib AA Faigel DO | 2012 | Gastrointest Endosc Clin N Am2012，22，2： | 1 |
| 3 | Optimal design of passive linear suspension using genetic algo-rithm 显示文摘 | Alkhatib R Nakhaie Jazar G Golnaraghi M F | 2004 | Journal of Sound and Vibration2004，275，： | 1 |
| 4 | Optimal design of passive linear suspension using genetic algorithm显示文摘 | Alkhatib R Nakhaie Jazar G Golnaraghi M F | 2004 | Journal of Sound and Vibration2004，275，： | 1 |
| 5 | Optimization of methacrylic acid ester copolymers blends as controlled release coatings using response surface methodology显示文摘 | ALKHATIB H S SAKR A | 2003 | Pharm Dev Tech2003，8，： | 1 |
| 6 | Optimal design of passive linear suspension using genetic algorithm显示文摘 | Alkhatib R Nakhaie Jazar G Colnaraghi M F | 2004 | Journal of Sound and Vibration2004，，275： | 1 |
| 7 | STRL33, A Novel Chemokine Receptor-like Protein, Functions as a Fusion Cofactor for Both Macrophage -tropic and T Cell Line - tropic HIV - 1 显示文摘 | Liao F Alkhatib G Penden K | 1997 | J Exp Med1997，185，11： | 1 |
| 8 | An estimate of hospitalization cost for elderly patients with acute upper gastrointestinal bleeding in the USA显示文摘 | Alkhatib A A Abubakr S M Elkhatib F A | 2009 | Dig Dis Sei2009，54，3： | 1 |
| 9 | CC CKR5:a RANTES,MIP-1α,MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1显示文摘 | Alkhatib G Combadiere C Broder CC | 1996 | Science1996，272，： | 1 |
| 10 | CC CKR5: RANTES,MIP-1α, MIP-1βreceptor as a fusion cofactor for macrophage-tropic HIV-1显示文摘 | Comabdiere C Broder CC | 1996 | Science1996，272，5270： | 1 |
| 11 | Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5 : Studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk 显示文摘 | Zimmerman PA Buckler-White A Alkhatib G | 1997 | Mol Med1997，3，1： | 1 |
| 12 | Pathogenicity of adisease associated human IL-4 receptor allele in experi-mental asthma显示文摘 | Taehdjian R Mathias C Alkhatib S | 2009 | J Exp Med2009，206，10： | 1 |
| 13 | CC CKR5:a RANTES,MIP-1 alpha,MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1显示文摘 | Alkhatib G Combadiere C Broder C C | 1996 | Science1996，272，： | 1 |
| 14 | Root mean square optimization criterion for vibration behavior of linear quarter car using analytical methods显示文摘 | NAKHAIE JAZAR G ALKHATIB R GOLNARAGHI M F | 2006 | Vehicle System Dynamics2006，44，6： | 1 |
| 15 | Naturally occurring splice variant of CXCL12/SDF-1 is a potent HIV-1 inhibitorwith weak chemotaxis activity 显示文摘 | Altenburg J QW Jin G Alkhatib | 2007 | J Virol2007，81，15： | 1 |
| 16 | Prevalence of self-assessed tooth discolouration in the United Kingdom 显示文摘 | Alkhatib M N Holt R Bedi R | 2004 | Journal of Dentistry2004，32，7： | 1 |
| 17 | Acute mechanical injury of the human intervertebral disc : link to degeneration and pain显示文摘 | Alkhatib B Rosenzweig DH Krock E | 2014 | Eur Cell Mater2014，28，： | 1 |
| 18 | Active structural vibra- tion control: a review显示文摘 | Alkhatib R Golnaraghi M F | 2003 | Shock and Vibration Digest2003，35，5： | 1 |
| 19 | Morphological peculiarities of the deep infratemporal fossa in advanced age显示文摘 | Michael Lüdinghausen Ikuo Kageyama Masahiro Miura Mohamed AlKhatib | 2006 | Surgical and Radiologic Anatomy2006，，3： | 1 |
| 20 | Synthesis and in vitro behavior of iron-crosslinked N-methyl and N-benzyl hydroxamated derivatives of alginic acid as controlled release carriers 显示文摘 | ALKHATIB H S TAHA M O AIEDEH K M BISTANJI Y | 2006 | European Polymer Journal2006，42，10： | 1 |
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