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| 1 | Ethnopharmacology,phytochemistry,and biological activities of Cymbopogon citratus(DC.) Stapf extracts显示文摘Cymbopogon citratus is a widely distributed perennial herb belonging to the Poaceae family and has been extensively consumed for its medicinal,cosmetic,and nutritional effects for centuries.A large number of reports have been published describing the pharmacological,biological,and therapeutic actions of this herb.In this review,we summarized the literatures on related studies(up to January,2014) that highlighted the pharmacologic and biological effects of the major phytochemicals isolated from C.citratus extracts and its essential oil.The components of the essential oils found in C.citratus have a similar pharmacokinetic properties,including absorption,distribution,metabolism,and excretion.They are quickly absorbed following oral,pulmonary,and dermal administration.Based on the published reports,it can also be inferred that,after absorption from the small intestine,some phytochemicals in C.citratus can undergo oxidation,glucuronidation,sulfation,and/or O-methylation.Excretion is through urine,feces and/or expired volatiles.The biotransformation reactions of C.citratus bioactive constituents are essential for its relatively safe consumption and therapeutic applications.The data available so far warrant further studies evaluating C.citratus pharmacokinetics.Reliable pharmacokinetic data in humans would be critical for a better understanding of the the systemic handling of C.citratus. | Christopher E Ekpenyong Ernest Akpan Azah Nyoh | 2015 | Chinese Journal of Natural Medicines2015，13，5： | 3 |
| 2 | Antiplasmodial and antipyretic studies on root extracts of Anthocleista djalonensis against Plasmodium berghei显示文摘 | Enomfon J Akpan Jude E Okokon Idongesit C Etuk | 2012 | Asian Pacific Journal of Tropical Disease2012，，1： | 2 |
| 3 | Clinical pharmacologic investigations with carvedilot,a new P-blocher with direct vasodilator activity显示文摘 | Von Moellendorff E Abshagen V Akpan W | 1986 | Clic Pharmacol Ther1986，39，： | 1 |
| 4 | Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/ neuron loss and improves neurological function after stroke显示文摘 | Akpan N Serrano-Saiz E Zacharia BE | 2011 | J Neurosci2011，31，24： | 1 |
| 5 | Heavy metal trends in the Calabar River, Nigeria显示文摘 | AKPAN E EKPE U J IBOK U J | 2002 | Environmental Geology2002，42，1： | 1 |
| 6 | Mould temperature and mechanical properties of cast aluminum-silicon carbide composite 显示文摘 | ADEOSUN S O AKPAN E I ABIODUN D | 2013 | International Journal of Materials and Chemistry2013，3，4： | 1 |
| 7 | Case histories with sinter hardening low alloy steel powder显示文摘 | Akpan E L' Esperance G Roy L | 1993 | Metal Powder Report1993，48，10： | 1 |
| 8 | Tin (11) chloride a suitable wetting agent for AA1200-SiC composites 显示文摘 | ADEOSUN S O AKPAN E I BALOGUN S A ABDULMUNIM A S | 2014 | International Journal of Chemical Nuclear Metallurgical and Materials Engineering2014，8，4： | 1 |
| 9 | An inves- tigation of the effects of microstructure on dwell fatigue crack growth in Ti-6242 显示文摘 | McBagonluri F Akpan E Mercer C | 2005 | Materials Science and Engineering A2005，405，： | 1 |
| 10 | Mechanisms of neuronal death in disease:defining the models and the players显示文摘 | Ribe EM Serrano-Saiz E Akpan N | | 0，，02： | 1 |
| 11 | An investigation of the effects of microstructure on dwell fatigue crack growth in Ti-6242 显示文摘 | McBAGONLURI F AKPAN E MERCER C SHEN W SOBOYEJO W O | 2005 | Materials Science and Engineering A2005，405，： | 1 |
| 12 | On the φ0- stability of comparison differential systems显示文摘 | AKPAN E P AKINYELE O | 1992 | Journal of Mathematical Analysis and Applications1992，164，2： | 1 |
| 13 | Clinical pharmacologic investigations with carvedilol,a new β blocher with direct vasodilator activity显示文摘 | Von Moellendorff E Abshagen U Akpan W | 1986 | Clin Pharmcol Ther1986，39，： | 1 |
| 14 | Job-shop sequencing problems via network scheduling technique显示文摘 | Akpan E O P | 1996 | International Journal of Operations & Production Management1996，16，3： | 1 |
| 15 | On the φo-stability of comparison differential systems显示文摘 | AKPAN E P AKINYELE O | 1992 | J Math Anal Appl1992，164，： | 1 |
| 16 | An investigation of the effects of microstructure on dwell fatigue crack growth in Ti-6242显示文摘 | MCBAGONLURI F AKPAN E MERCER C SHEN W SOBOYEJO W O | 2005 | Materials Science and Engineering A2005，405，： | 1 |
| 17 | Gastroprotective effect of the aqueous leaf extract of Guiera senegalensis in Albino rats显示文摘Objective:To evaluate the effect of aqueous leaf extract of Guiera senegalensis(G.senegalensis)on gastric mucosal damage using different ulcer models.Methods:Considering the above claims,the present study was undertaken to validate the gastroprotective potential of the aqueous leaf extract of this plant against ethanol,water immersion and Aspirin induced ulcer models.Results:The leaf extract(50,100 and 200 mg/kg,p.o.)significantly(P<0.05)decreased the ulcer index in all assays used.Conclusions:The results obtained,provide strong evidence of antiulcer activity of the leaf extract of G.senegalensis and support the traditional uses of the plant for the treatment of ulcer. | Akuodor GC Essien AD David-Oku E Chilaka kC Akpan JL Ezeokpo B Ezeonwumelu JOC | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，10： | 1 |
| 18 | Probabilistic risk assessment of solid-propellant rocket motors显示文摘 | Akpan U O Dunbar T E Franklin C W | 2008 | Journal of Spacecraft and Rockets2008，40，3： | 1 |
| 19 | On the φ0-stability of comparison differential systems显示文摘 | AKPAN E P AKINYELE O | 1992 | Journal of Mathematical Analysis and Applications1992，164，2： | 1 |
| 20 | Clinical pharmacologic investigations with carvedilol, a new β-blocher with direct vasodilator activity显示文摘 | Von Moellendorff E Abshagen U Akpan W | 1986 | Clin Pharmacol Ther1986，39，： | 1 |
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