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		题名	作者	年代	出处	被引量
	1	Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients显示文摘AIM: To determine the composition of both fecal and duodenal mucosa-associated microbiota in irritable bowel syndrome (IBS) patients and healthy subjects using molecular-based techniques. METHODS: Fecal and duodenal mucosa brush samples were obtained from 41 IBS patients and 26 healthy subjects. Fecal samples were analyzed for the composition of the total microbiota using fluorescent in situ hybridization (FISH) and both fecal and duodenal brush samples were analyzed for the composition of bif idobacteria using real-time polymerase chain reaction. RESULTS: The FISH analysis of fecal samples revealed a 2-fold decrease in the level of bifidobacteria (4.2 ± 1.3 vs 8.3 ± 1.9, P < 0.01) in IBS patients compared to healthy subjects, whereas no major differences in other bacterial groups were observed. At the species level, Bifidobacterium catenulatum levels were significantly lower (6 ± 0.6 vs 19 ± 2.5, P < 0.001) in the IBS patients in both fecal and duodenal brush samples than in healthy subjects.CONCLUSION: Decreased bifidobacteria levels in both fecal and duodenal brush samples of IBS patients compared to healthy subjects indicate a role for microbiotic composition in IBS pathophysiology.	Angèle PM Kerckhoffs Melvin Samsom Michel E van der Rest Joris de Vogel Jan Knol Kaouther Ben-Amor Louis MA Akkermans	2009	World Journal of Gastroenterology2009，15，23：	33
	2	手术后胃排空紊乱显示文摘在过去的10年里,对胃进行手术的次数已明显下降。尽管如此,人们仍对讨论手术后胃排空功能紊乱十分感兴趣。在任何外科手术的头几天,都可以观察到胃排空障碍。这一情况(通常又称为手术后胃无力或手术后胃轻瘫)大多数为自限性,但也时常向外科医生提出一些严肃的问题。许多接受胃手术的病人术后晚些时候表现出的症状和体征都与残胃排空和动力紊乱有关。胃动力学病理生理知识及及胃手术后排空知识对满足病人需要的手术类型是重要的。本文对可发生于任何类型手术后(不仅仅是胃手术)的急性胃动力紊乱进行了讨论。	Andre JPM Smout Louis MA Akkermans	1996	中国实用外科杂志1996，16，5：	4
	3	Decreased mechanical efficiency in clinically stable patients with COPD 显示文摘	Baarends EM Schols AMWJ Akkermans MA	1997	Thorax1997，52，：	1
	4	Decreased mechanical efficiency in clinically stable patients with COPD 显示文摘	Baarends EM Schols AM Akkermans MA	1997	Thorax1997，52，11：	1

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