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		题名	作者	年代	出处	被引量
	1	The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis显示文摘Breast cancer is the most prevalent cancer worldwide,and metastasis is the leading cause of death in cancer patients.Human monocyte chemoattractant protein-1(MCP-1/CCL2)was isolated from the culture supernatants of not only mitogen-activated peripheral blood mononuclear leukocytes but also malignant glioma cells based on its in vitro chemotactic activity toward human monocytes.MCP-1 was subsequently found to be identical to a previously described tumor cell-derived chemotactic factor thought to be responsible for the accumulation of tumor-associated macrophages(TAMs),and it became a candidate target of clinical intervention;however,the role of TAMs in cancer development was still controversial at the time of the discovery of MCP-1.The in vivo role of MCP-1 in cancer progression was first evaluated by examining human cancer tissues,including breast cancers.Positive correlations between the level of MCP-1 production in tumors and the degree of TAM infiltration and cancer progression were established.The contribution of MCP-1 to the growth of primary tumors and metastasis to the lung,bone,and brain was examined in mouse breast cancer models.The results of these studies strongly suggested that MCP-1 is a promoter of breast cancer metastasis to the lung and brain but not bone.Potential mechanisms of MCP-1 production in the breast cancer microenvironment have also been reported.In the present manuscript,we review studies in which the role of MCP-1 in breast cancer development and progression and the mechanisms of its production were examined and attempt to draw a consensus and discuss the potential use of MCP-1 as a biomarker for diagnosis.	Teizo Yoshimura Chunning Li Yuze Wang Akihiro Matsukawa	2023	Cellular & Molecular Immunology2023，20，7：	1
	2	Long term changes in platelet counts after H. pylori eradication in non-ITP patients显示文摘	Yoshihiro Matsukawa Maho Iwamoto Kimitoshi Kato Shigeaki Mizuno Yasuhiro Gon Akihiro Hemmi Natalia Shirinskaya Jin Takeuchi Shigemasa Sawada	2010	Platelets2010，，8：	1
	3	Intervertebral Disc Cells Produce Tumor Necrosis Factor α, Interleukin-1β, and Monocyte Chemoattractant Protein-1 Immediately After Herniation: An Experimental Study Using a New Hernia Model显示文摘	Masakazu Yoshida Takafumi Nakamura Akira Sei Taro Kikuchi Katsumasa Takagi Akihiro Matsukawa	2005	Spine2005，，1：	1
	4	Rupture and drug release characteristics of multi-reservoir type microspheres with poly( dl -lactide- co -glycolide) and poly( dl -lactide)显示文摘	Akihiro Matsumoto Yasuhisa Matsukawa Yuji Horikiri Takehiko Suzuki	2006	International Journal of Pharmaceutics2006，，1：	1
	5	Drug release characteristics of muhi-reservior type microspheres with poly ( DL-lactlde-eo-glycolide) and poly(DL-laetide)显示文摘	Akihiro Matsumoto Yasuhisa Matsukawa Takehiko Suzuki el al	2005	Journal of controlled release2005，106，：	1
	6	Development of Electrical Discharge Coating Machine (EDCOAT) 显示文摘	Akihiro Goto Toshio Moro Koei Matsukawa	2000	Journal of the Japan Society of Electrical Machining Engineers2000，34，3：	1

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