|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Cetuximab,paclitaxel,carboplatin and radiation for esophageal and gastric cancer显示文摘 | Suntharalingam M Dipertrillo T Akerman P | 2006 | J Clin Oncol2006，24，18： | 1 |
| 3 | Flow cytometreic S-phase fraction in soft tissue Sarcoma:prognostic importance analysed in 160 patients显示文摘 | Ferno M Akerman M | 1997 | Br J Cancer1997，75，1： | 1 |
| 4 | Nanocrystal targeting in vivo显示文摘 | Akerman M E Chan W C W Laakkonen P | 2002 | Proceedings of the Na- tional Academy of Sciences of the United States of Amer- ica2002，99，12： | 1 |
| 5 | Single-file electrophoretic transport and counting of individual DNA molecules in surfactant nanotubes显示文摘 | Tokarz M Akerman B Olofsson J | 2005 | Proc Natl Acad Sci USA2005，102，26： | 1 |
| 6 | Core-needle biopsy performed by the cytopathologist:a technique to complement fine-needle aspiration of soft tissue and bone lesions显示文摘 | Domanske HA Akerman M Carlén B | | 0，，04： | 1 |
| 7 | Low pH treatment protects litchi fruit colour显示文摘 | Zauberman G Ronen R Akerman M | 1989 | Acta Hort1989，269，： | 1 |
| 8 | Trimethylamin- uria is caused by mutations of the FM03 gene in a North American Cohort显示文摘 | Akerman B R Lemass H Chow L M | 1999 | Mol Genet Metab1999，68，1： | 1 |
| 9 | Pulmonary manifestations of AIDS:review of 106 episodes显示文摘 | Akerman M Orenstein M | 1986 | Radiology1986，161，1： | 1 |
| 10 | The management of break through pain during labour 显示文摘 | Akerman N Dresner M | 2009 | CNS Drugs2009，23，： | 1 |
| 11 | Nanocrystal targeting in vivo显示文摘 | AKERMAN M E CHAN W C LAAKKONEN P | 2002 | Proic Natl Acad Sci USA2002，99，12： | 1 |
| 12 | Nanocrystal Targeting in Vivo显示文摘 | AKERMAN M E CHAN W LAAKKONEN P | 2002 | Proc Natl Acad Sci USA2002，99，12： | 1 |
| 13 | Combined morphologic and karyotypic study of 59 atypical lipomatous tumors(evaluation of their relationship and differential diagnosis with other adipose tissue tumors:a report of the CHAMP study group)显示文摘 | Rosai J Akerman M Dal Cin P | 1996 | Am J Surg Pathol1996，20，10： | 1 |
| 14 | Nanocrystal targeting in vivo显示文摘 | Akerman M E Chan W C Laakkonen P | 2002 | Science2002，99，12： | 1 |
| 15 | Flow cytometreic S-phase fraction in soft tissue Sarcoma:prognostic importance analysed in 160 patients显示文摘 | Gustafson P Ferno M Akerman M | 1997 | Br J Cancer1997，75，1： | 1 |
| 16 | Integration of pre-and postharvest treatments for the control of black spot caused by Alternaria alternata in stored persimmon fruit显示文摘 | Kobiler I Akerman M Huberman L | 2011 | Postharvest Biology and Technol ogy2011，59，2： | 1 |
| 17 | Postharvest retention of the red colour of litchi fruit pericarp显示文摘 | Zauberman G Ronen R Akerman M | 1991 | ScientiaHorticulturae1991，47，： | 1 |
| 18 | Postharvest retention of the red colour of litchi fruit pericarp显示文摘 | Zauberman G Ronen R Akerman M | 1991 | Scientia Horticlturae1991，47，： | 1 |
| 19 | Flow cytomettic S-phase fraction in soft tissue sarcoma: prognostic importance analysed in 160 patients显示文摘 | Gustafson P Ferno M Akerman M | 1997 | Br J Cancer1997，75，1： | 1 |
| 20 | Nanocrystal targeting in vivo显示文摘 | M E Akerman W C Chan P Laakkonen | 2002 | Proceedings of the National Academy of Sciences2002，99，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员