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| 1 | A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration显示文摘Age-related macular degeneration(AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040.Genetics,age,diabetes,gender,obesity,hypertension,race,hyperopia,iris-color,smoking,sun-light and pyroptosis have varying roles in AMD,but oxidative stress-induced inflammation remains a significant driver of pathobiology.Eye is a unique organ as it contains a remarkable oxygengradient that generates reactive oxygen species(ROS) which upregulates inflammatory pathways.ROS becomes a source of functional and morphological impairments in retinal pigment epithelium(RPE),endothelial cells and retinal ganglion cells.Reports demonstrated that hydrogen sulfide(H_2S) acts as a signaling molecule and that it may treat ailments.Therefore,we propose a novel hypothesis that H_2S may restore homeostasis in the eyes thereby reducing damage caused by oxidative injury and inflammation.Since H_2S has been shown to be a powerful antioxidant because of its free-radicals' inhibition properties in addition to its beneficial effects in age-relatedconditions,therefore,patients may benefit from H_2S salubrious effects not only by minimizing their oxidant and inflammatory injuries to retina but also by lowering retinal glutamate excitotoxicity. | Akash K George Mahavir Singh Rubens Petit Homme Avisek Majumder Harpal S SANDhu Suresh C Tyagi | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 2 | 简易转速测量系统设计显示文摘介绍了一种基于定时器的转速测量系统的设计与开发。使用直流电动机的转轴来测量其转速,定时器IC 555用于不稳定模式。使用数字存储示波器(DSO)测量的定时器输出波形的频率几乎与转轴的转速成线性比例,而这个转速又与外部输入电压水平的变化成线性关系,由此得到了定时器输出波形频率与转速之间的线性关系。该系统的主要优点是线性输入-输出,体积小,便于携带且成本低。 | Akash Kumar Anindya Debnath Antar Banik Kabirul Islam Mondal Partha Pratim Biswas Rik Bhattacharyya T K Maiti | 2020 | Journal of Measurement Science and Instrumentation2020，11，2： | 2 |
| 3 | Enzymatic modification of guar solutions 显示文摘 | Akash Tayal Robert M K | 2007 | Macromolecules2007，，5： | 1 |
| 4 | Interleukin-1 receptor an- tagonist:a new therapy for type 2 diabetes mellitus显示文摘 | Akash MS Sben Q Rehman K | 2012 | J Pharm Sci2012，101，5： | 1 |
| 5 | Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus 显示文摘 | Akash M S Rehman K Chert S | 2013 | J Cell Biochem2013，114，3： | 1 |
| 6 | Oral bioavailability enhancement of exemestane from self- microemulsifying drug delivery system 显示文摘 | Ajeet K S Akash C Anshumali A | 2009 | Pharm Sci Tech2009，10，3： | 1 |
| 7 | Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus显示文摘 | Akash MS Rehman K Chen S | 2013 | J Cell Biochem2013，114，3： | 1 |
| 8 | Endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of central lung parenchymal lesions显示文摘 | AKASH V KYEONGMAN J WONJUNG K | 2013 | Yonsei Medical Journal2013，54，3： | 1 |
| 9 | Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus显示文摘 | AKASH M S REHMAN K CHEN Shuqing | 2013 | Journal of Cellular Biochemistry2013，114，3： | 1 |
| 10 | Interleukin-1 receptor antagonist: a new therapy for type 2 diabetes mellitus 显示文摘 | Akash MS Shen Q Rehman K | 2012 | J Pharm Sci2012，101，： | 1 |
| 11 | Assessment of release kinetics,stability and polymer interaction of poloxamer 407basedthermosensitive gel of interleukin-1 receptor antagonist 显示文摘 | AKASH MS REHMAN K SUN H | 2014 | Pharm Dev Techno12014，19，3： | 1 |
| 12 | Enhanced 5-HT(2A) receptor status in the hypothalamus and corpus striatum of ethanol-treated rats 显示文摘 | Akash K G Balarama K S Paulose C S | 2008 | Cell Mol Neurobiol2008，28，7： | 1 |
| 13 | Growth and char- acterization of Mg2Zn1-x O thin films by aerosol-assisted chemical vapor deposition(AACVD) 显示文摘 | AKASH S KAUSHIK V K PRASHER D | 2014 | Electronic Materials Letters2014，10，1： | 1 |
| 14 | Jitter’ s alpha stable distribu-tion behavior显示文摘 | Bandhopadhya T K Manish S Akash T | 2013 | International Journal of Computer Technologyand 曰ectronics Engineering2013，3，1： | 1 |
| 15 | Interleukin-1 receptor antagonist:a new therapy for type 2 diabetes mellite显示文摘 | Akash MS Shen Q Rehman K | 2012 | J Pharm Sci2012，101，5： | 1 |
| 16 | Assessment of release kinetics, stability and polymer interaction of poloxamer 407-based thermosensitive gel of interleukin-1 receptor antagonist显示文摘 | Akash M S H Rehman K Sun H | 2013 | Pharm Dev Technol2013，19，3： | 1 |
| 17 | Ajax asynchronous database refresh 显示文摘 | Akash K Singh | 2012 | International Journal of Information and Communication Technology Research2012，2，8： | 1 |
| 18 | Assessment of releasekinetics,stability and polymer interaction of poloxamer 407 -basedthermosensitive gel of interleukin-1 receptor ntagonist 显示文摘 | AKASH MS REHMAN K SUN H | 2013 | PharmDevelop Technol2013，19，3： | 1 |
| 19 | Recent progress in biomedical applications of Pluronie ( PF127 ) : Pharmaceutical perspectives 显示文摘 | Akash MS Rehman K | 2015 | J Control Re- lease2015，209，7： | 1 |
| 20 | 查看详情显示文摘 | Lei Y Zhang S Fang L Akash M S H Shi W Sun K Xu Y Chen S | | 0，，： | 1 |
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