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| 1 | A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration显示文摘Age-related macular degeneration(AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040.Genetics,age,diabetes,gender,obesity,hypertension,race,hyperopia,iris-color,smoking,sun-light and pyroptosis have varying roles in AMD,but oxidative stress-induced inflammation remains a significant driver of pathobiology.Eye is a unique organ as it contains a remarkable oxygengradient that generates reactive oxygen species(ROS) which upregulates inflammatory pathways.ROS becomes a source of functional and morphological impairments in retinal pigment epithelium(RPE),endothelial cells and retinal ganglion cells.Reports demonstrated that hydrogen sulfide(H_2S) acts as a signaling molecule and that it may treat ailments.Therefore,we propose a novel hypothesis that H_2S may restore homeostasis in the eyes thereby reducing damage caused by oxidative injury and inflammation.Since H_2S has been shown to be a powerful antioxidant because of its free-radicals' inhibition properties in addition to its beneficial effects in age-relatedconditions,therefore,patients may benefit from H_2S salubrious effects not only by minimizing their oxidant and inflammatory injuries to retina but also by lowering retinal glutamate excitotoxicity. | Akash K George Mahavir Singh Rubens Petit Homme Avisek Majumder Harpal S SANDhu Suresh C Tyagi | 2018 | International Journal of Ophthalmology(English edition)2018,11,5: | 3 |
| 2 | Complementary roles of interventional radiology and therapeutic endoscopy in gastroenterology显示文摘Acute upper and lower gastrointestinal bleeding, enteral feeding, cecostomy tubes and luminal strictures are some of the common reasons for gastroenterology service. While surgery was initially considered the main treatment modality, the advent of both therapeutic endoscopy and interventional radiology have resulted in the paradigm shift in the management of these conditions. In this paper, we discuss the patient's work up, indications, and complementary roles of endoscopic and angiographic management in the settings of gastrointestinal bleeding, enteral feeding, cecostomy tube placement and luminal strictures. These conditions often require multidisciplinary approaches involving a team of interventional radiologists, gastroenterologists and surgeons. Further, the authors also aim to describe how the fields of interventional radiology and gastrointestinal endoscopy are overlapping and complementary in the management of these complex conditions. | David M Ray Indu Srinivasan Shou-jiang Tang Andreas S Vilmann Peter Vilmann Timothy C McCowan Akash M Patel | 2017 | World Journal of Radiology2017,9,3: | 2 |
| 3 | Investigation of simultaneous coal and lignin liquefaction Kinetic studies显示文摘 | Akash B A Muchore C B Koropchak J A | 1992 | Energy & Fuel1992,6,5: | 1 |
| 4 | Investigation of simultaneous coal and lignin liquefaction--Kinetic studies显示文摘 | Akash B A Muchore C B Koropchak J A | 1992 | Energy & Fuel1992,6,5: | 1 |
| 5 | Oral bioavailability enhancement of exemestane from self- microemulsifying drug delivery system 显示文摘 | Ajeet K S Akash C Anshumali A | 2009 | Pharm Sci Tech2009,10,3: | 1 |
| 6 | Ubiquitin is part of the retrovirus budding machinery 显示文摘 | Akash P Vintent C John W W | 2000 | Proc Natl Acad Sci USA2000,97,13: | 1 |
| 7 | Investigation of simultaneous coal and lignin liquefaction-Kinetic studies 显示文摘 | Akash B A Muchore C B Koropehak J A | 1992 | Energy & Fuel1992,6,5: | 1 |
| 8 | Enhanced 5-HT(2A) receptor status in the hypothalamus and corpus striatum of ethanol-treated rats 显示文摘 | Akash K G Balarama K S Paulose C S | 2008 | Cell Mol Neurobiol2008,28,7: | 1 |
| 9 | Trapa natans (Water Chestnut): an overview 显示文摘 | Shalabh B Akash J Jasmine C | 2012 | International Research Journal of Pharmacy2012,3,6: | 1 |
| 10 | Rate of chitobiase degradation as a measure of development rate in planktonic Crustacea 显示文摘 | Akash R John C | 2000 | Canadian Journal of Fisheries and Aquatic Sci- ences2000,57,: | 1 |
| 11 | Investigation of Simultaneous Coal and Lignin Liquefaction-kinetic Studies 显示文摘 | Akash B A Muehore C B Koropchak J A | 1992 | Energy & Fuel1992,6,5: | 1 |
| 12 | Coliquefaction of coal and black liquor to environmentally acceptable liquid fuels显示文摘 | KIM J LALVANI S B MUCHMORE C B AKASH B A | 1999 | Energy Sources1999,21,9: | 1 |
| 13 | Investigation of simultaneous coal and lignin liquefaction-Kinetic studies显示文摘 | Akash B A Muchore C B Koropchak J A | | 0,,05: | 1 |