|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dysregulation of gastric H,K-ATPase by cigarette smoke extract显示文摘AIM:To test whether the expression and activity of H,K-ATPase in parietal cells would be affected by cigarette smoke extract.METHODS: Extracts of cigarette smoke were administered into mice by gastric gavage (5 mg/kg body weight/day) for 3 d or in drinking water for 7 or 14 d. For the latter, each day a mouse consumed 5 mL water containing extracts of two cigarettes, on average. Control littermate mice received only vehicle. To compare the amount of H,K-ATPase in control and smoke-treated mice, the stomach was processed for Western blotting and immunohistochemical analysis using monoclonal antibodies specific for α- or β-subunits of H,K-ATPase. The p-nitrophenylphospatase activity assay was used as a measurement for K-dependent H,K-ATPase activity.RESULTS: Probed transblots showed an increase in the amount of H,K-ATPase in smoke-treated mice which was confirmed by immunohistochemistry and was found to be due to increased amounts of protein per parietal cell rather than an increased parietal cell number. The increase in the amount of H,K-ATPase was associated with an enhancement of its enzymatic activity. K-dependent activity in control and smoke-treated mice was significantly different (respectively, 0.12 μmol/mg vs 0.27 μmol/mg per minute, P<0.05).CONCLUSION: Administration of cigarette smoke extract is associated with an increase in the amount and activity of H,K-ATPase and hence, smokers are susceptible to development of peptic ulcer. | Muna Hammadi Mohamed Adi Rony John Ghalia AK Khoder Sherif M Karam | 2009 | World Journal of Gastroenterology2009，15，32： | 7 |
| 2 | ABA is an essential signal for plant resistance to pathogens affecting JA biosynthesis and the activation of de- fenses in arabidopsis 显示文摘 | ADIE B A T PEREZ-PEREZ J PEREZ-PEREZ M M | 2007 | Plant cell2007，19，5： | 1 |
| 3 | Canopy fogging of an overstory tree-recommendations for standardization显示文摘 | Adis J Y Basset A Floren P M Hammond and K E Linsenmair | | 0，，： | 1 |
| 4 | Perceptual audio data conceal ment and watemarking scheme using direct frequency domain substitution显示文摘 | Tio C M M McLoughlin I V Adi R W | 2002 | Vision Image and Signal Processing IEE Proceedings2002，149，6： | 1 |
| 5 | A method for obtain- ingdigital signatures and public-key cryptosystems显示文摘 | Ronald Rivest Adi Shamir Leonard M Adleman | 1978 | ACM1978，21，2： | 1 |
| 6 | Symptomatic occipital lobe epilepsy following neonatal hypoglycemia显示文摘 | Caraballo RH Sakr D Mozzi M Guerrero A Adi JN Cersosimo RO | 2004 | Pediatr Neurol2004，31，1： | 1 |
| 7 | Efect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells显示文摘 | Mal adi P Xu Y Chiou M | | 0，，： | 1 |
| 8 | Cryotherapy after total knee arthroplasty: a systematic review and meta-analysis of random- ized controlled trials 显示文摘 | Adie S Naylor J M Harris I A | 2010 | J Arthroplasty2010，25，5： | 1 |
| 9 | Repairing Organizational Legitimacy Following Information Technology, (IT) Material Weaknesses : Executive Turnover, IT Expertise, and IT System Upgrades 显示文摘 | Haislip J Z Adi M Richardson V J Juan M S | 2016 | Journal of Information Systems2016，30，1： | 1 |
| 10 | A comparison of synaptophysin,chromogranin,and L2Dopa decarboxylase as markers for neuroendocrine differentiation in lung cancerlines显示文摘 | Sandra M Jensen Adi F Gazdar F C | 1990 | Cancer Rese1990，50，15： | 1 |
| 11 | BAB is an Essential Signal for Plantresistane to Pathogens Affecting JA Biosynthesis and the Activation of Defenses in Arabidopsis显示文摘 | ADIE B PEREZ-PEREZ J PEREZ-PEREZ M M | 2007 | Plant Cell2007，19，： | 1 |
| 12 | C-reactive protein and outcome after first-ever ischemic stroke 显示文摘 | aDi Napoli M Di Gianfilippo G Sollecito A | 2000 | Stroke2000，31，1： | 1 |
| 13 | Metallothionein-bound cadmium in the gut of the insect Orchesella cincta (Collembola) in relation to dietary cadmium exposure显示文摘 | Paul J Hensbergen Martin J.M van Velzen Rully Adi Nugroho Marianne H Donker Nico M van Straalen | 2000 | Comparative Biochemistry and Physiology Part C: Comparative Pharmacology and Toxicology2000，，1： | 1 |
| 14 | Deubiquitinating enzymes are in(trinsic to proteasome function) 显示文摘 | Adi G Glickman M H | 2004 | Current Protein and Peptide Science2004，5，4： | 1 |
| 15 | Exchange bias u- sing a spin glass显示文摘 | ALl M ADIE P MARROWS C H | 2007 | Nature Materials2007，6，： | 1 |
| 16 | ABA is an essential signal for plant resistance to pathogens af- fecting JA biosynthesis and the activation of defenses in Ara- bidopsis 显示文摘 | ADIE B A T PEREZ-PEREZ J PEREZ-PEREZ M M | 2007 | Plant Cell2007，19，5： | 1 |
| 17 | Rural sustainability under threat in Zimbabwe-Simulation of future land use/cover chang- es in the Bindura district based on the Markov-cellular automa- ta model显示文摘 | Kamusoko C Aniya M Adi B | 2009 | Applied Geography2009，29，3： | 1 |
| 18 | Rural sustainability under threat in Zimbabwe-simulation of future land use/cover changes in the Bindura district based on the Markov-cellular automata model显示文摘 | Kamusoko C Aniya M Adi B | 2009 | Applied Geography2009，29，3： | 1 |
| 19 | Heterogeneity of serotonergic response in treatment - refractory schizophrenia patients显示文摘 | Lindermayer JP Adi tyanjee Vital - Herne M | 1997 | Biol p sychiatry1997，42，： | 1 |
| 20 | ABA is an essential signal for plant resistance to pathogens affecting JA biosynthesis and the activation of defenses in Arabidopsis显示文摘 | ADIE B A T PEREZ-PEREZ J PEREZ-PEREZ M M GODOY M SANCHEZ-SERRANO J J SCHMELZ E A SOLANO R | 2007 | Plant Cell2007，19，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员