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| 1 | Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial显示文摘 | JY Douillard D Cunningham AD Roth M Navarro RD James P Karasek P Jandik T Iveson J Carmichael M Alakl G Gruia L Awad P Rougier | 2000 | The Lancet2000，，9209： | 4 |
| 2 | 视网膜病变、视网膜微血管异常与脑卒中、脑血管病的关系显示文摘视网膜循环异常可能与脑血管病有关。该研究基于英国的三民族人口的基础队列调查了视网膜微血管异常与脑卒中和亚临床脑梗死及脑白质病变之间的相关性。方法:纳入1185名受试者[年龄(68.8±6.1)岁,77%为男性]进行视网膜成像和脑磁共振成像。利用磁共振成像识别脑梗死和脑白质高信号,对视网膜病变进行分级,并测量视网膜血管参数。 | 刘莉 叶鹏 Hughes AD Falaschetti E Witt N Wijetunge S Thom SA Tillin T Aldington SJ Chaturvedi N | 2016 | 中华高血压杂志2016，24，11： | 2 |
| 3 | 冠状动脉内皮功能障碍患者胆固醇流出异常,高密度脂蛋白颗粒物浓度降低显示文摘冠状动脉内皮功能障碍(endothelial dysfunction,ED)是动脉粥样硬化早期标志,增加心血管事件发生风险。该研究假设胆固醇流出容量和高密度脂蛋白颗粒浓度(high-density lipoprotein particle concentration,HDL-PIMA)较高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)更能预测ED。 | 刘莉 叶鹏 Monette JS Hutchins PM Ronsein GE Wimberger J Irwin AD Tang C Sara JD Shao B Vaisar T Lerman A Heinecke JW | 2016 | 中华高血压杂志2016，24，6： | 2 |
| 4 | A systemic granulomatous response to Schistosoma mansoni eggs alters responsiveness of bone- marrow-derived macrophages to Toll-like receptor agonists 显示文摘 | Joshi AD Raymond T Coelho AL | 2008 | J Leukoc Biol2008，83，2： | 1 |
| 5 | Reevaluation of bone marrow-derived cells as a source for hepatocyte regeneration显示文摘 | Cantz T Sharma AD Jochheim-Richter A | 2004 | Cell Transplant2004，13，6： | 1 |
| 6 | Left ventricular dysfunction,natriuretic peptides,and mortality in an urban population显示文摘 | Cunningham AD Morrison CE | 2001 | Heart2001，86，： | 1 |
| 7 | TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionarylineage of enteropathogenic Escherichia coli 显示文摘 | Whale AD Hernandes RT Ooka T | 2007 | Microbiology2007，153，： | 1 |
| 8 | The programmned death-1 (PD-1) pathway regulates autoimmune diabetes in nonohese diabetic (NOD) mice显示文摘 | Ansari MJ Salarna AD Chitnis T | 2003 | J Exp Meal2003，198，1： | 1 |
| 9 | Massage for low back p-ain : an updated systematic review within ihe framework of the Co-chrane Back Review Group显示文摘 | Furlan AD Imamura M Dryden T | 2009 | Spine2009，34，16： | 1 |
| 10 | A comparative risk as- sessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a sys- tematic analysis for the Global Burden of Disease Study 2010 显示文摘 | Lim SS Vos T Flaxman AD | 2012 | Lancet2012，380，9859： | 1 |
| 11 | Vascular-targetedoverexpression of G protein-coupled receptor kinase-2 in transgen-ic mice attenuates beta-adrenergic receptor signaling and increasesresting blood pressure显示文摘 | Eckhart AD Ozaki T Tevaearai H | 2002 | Mol Pharmacol2002，61，4： | 1 |
| 12 | Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2protects against acetaminophen-induced liver toxicity显示文摘 | Patterson AD Shah YM Matsubara T Krausz KW Gonzalez FJ | 2012 | Hepatology2012，56，1： | 1 |
| 13 | NT-proBNP in- dependently predicts long term mortality after acute exacer- bation of copd - a prospective cohort study 显示文摘 | Hoiseth AD Omland T Hagve TA | 2012 | Respir Res2012，13，： | 1 |
| 14 | Linked chromosome 16q13 chemokines, macrophage derived chemokine, ractalkine, and thymus and activation regulated ehemokine, are expressed in human atherosclerotic lesions显示文摘 | Greaves DR Hakkinen T Lucas AD | 2001 | Arterioscler Thromb Vasc Biol2001，21，6： | 1 |
| 15 | Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro显示文摘 | Daniels J T Cambrey AD Occleston NL | 2007 | Invest Ophthalmol Vis Sci2007，48，3： | 1 |
| 16 | Thermal bonding of polymeric capillary electrophoresis microdevices in water 显示文摘 | Kelly Ry T Woolley Ad T | 2003 | Anal Chem2003，75，8： | 1 |
| 17 | Factors predicting perioperative cytokine response in patients undergoing liver transplantation显示文摘 | Miki C Mcmaster T Mayer AD | 2000 | Critical Care Medicine2000，28，2： | 1 |
| 18 | Insulin decreases the serum potassium concentration during the anhepatic stage of liver transplantation显示文摘 | Wolf AD Drenette L Kang T | 1993 | Anesthesiology1993，78，： | 1 |
| 19 | Incidence and mortality of acute lung injury and the acute respiratory distress syndrome in three Australian states 显示文摘 | Bersten AD Edibam C Hunt T | 2002 | Am J Respir Crit Care Med2002，165，4： | 1 |
| 20 | MPL515 mutations in myeloproliferative and other myeloid disorders:a study of 1182patients显示文摘 | Pardanani AD Levine RL Lasho T | | 0，，10： | 1 |
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