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| 1 | Anti-obesity and antihyperlipidaemic effect of Hunteria umbellata seed extract in experimental hyperlipidaemia显示文摘 | Adejuwon Adewale Adeneye Olufunmilayo Olaide Adeyemi Esther Oluwatoyin Agbaje | 2010 | Journal of Ethnopharmacology2010，，2： | 2 |
| 2 | Association of serum phosphate with vascular and valvular calcification in moderate CKD显示文摘 | Adeney KL Siscovic DS Ix JH | | 0，，： | 1 |
| 3 | Nephroprotective effects of the aqueous root extract of Harungana madagascarienses (L) in acute and repeated dose acetaminophen renal injured rats 显示文摘 | Adeneye AA Olagunju JA Benebo AS | 2008 | Int J Appl Res Nat Prod2008，1，1： | 1 |
| 4 | Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice 显示文摘 | Adeneye A A Amole O O Adeneye A K | 2006 | Fitoterapia2006，77，： | 1 |
| 5 | Anti-obesity and antihyperlipidaemic effect of Hunteria umbellata seed extract in experimental hyperlipidaemia显示文摘 | ADENEYE A A ADEYEMI O O AGBAJE E O | 2010 | Journal of Ethnopharmacology2010，130，2： | 1 |
| 6 | Association of serum phos-phate with vascular and valvular calcification in moderate CKD显示文摘 | Adeney K L Siscovick D S Ix J H | | 0，，02： | 1 |
| 7 | The leaf and seed aqueous extract of Phyllanthus amarus improves insulin resistance diabetes in experimental animal studies显示文摘 | Adejuwon Adewale Adeneye | 2012 | Journal of Ethnopharmacology2012，，3： | 1 |
| 8 | Performance of sheep fed soybean stover and cassava crumb bssed diets显示文摘 | SMITH J W DASHIELL K E | 1999 | Small Ruminant Research1999，31，3： | 1 |
| 9 | Performance of sheep fed soybean stover and cassava crumb based diets显示文摘 | ADENEYE J A SMITH J W DASHIELL K E | 1999 | Small Ruminant Research1999，31，3： | 1 |
| 10 | Hypoglycemic and hypolipidemic effects of meth-anol seed extract of Citrus paradisi Macfad(Rutaceae)in allox-an-induced diabetic Wistar rats显示文摘 | Adeneye AA | 2008 | Nig Q J Hosp Med2008，18，4： | 1 |
| 11 | Hypoglycemic and hypolipidemic effects of methanol seed extract of Citrus paradisi Macfad (Rutaceae) in alloxan-induced diabetic Wistar rats显示文摘 | ADENEYE A A | 2008 | Nigerian quarterly journal of hospital medicine2008，18，4： | 1 |
| 12 | Protective effect of the aqueous leaf and seed extract of Phyllanthus amarus on gentamicin and acetaminophen-induced nephrotoxic rats显示文摘 | ADENEYE A A BENEBO A S | 2008 | J Ethnopharmacol2008，118，2： | 1 |
| 13 | Using the Fast Orthogonal Search with First Term Reselection to Find Subharmonic Terms in Spectral Analysis显示文摘 | Donald R. McGaughey Michael J. Korenberg Kathryn M. Adeney Susan D. Collins G. J. M. Aitken | 2003 | Annals of Biomedical Engineering2003，，6： | 1 |
| 14 | Structural and functional vascular alterations and incident hypertension in normotensive adults:the Multi-Ethnic Study of Atherosclerosis显示文摘 | Peralta CA Adeney KL Shlipak MG | | 0，，01： | 1 |
| 15 | Protective effect of the aqueous leaf and seed extract of Phyllanthus amarus on gentamicin and acetaminophen-induced nephrotoxic rats 显示文摘 | Adeneye AA Benebo AS | 2008 | J Ethnopharmacol2008，118，2： | 1 |
| 16 | Weight losing, antihyperlipidemic and cardioprotective effects of the alkaloid fraction of Hunteria umbellata seed extract on normal and triton-induced hyperlipidemic rats显示文摘Objective: To investigate the weight losing, antihyperlipidemic and cardioprotective effects of the alkaloid fraction of Hunteria umbellata(H. umbellata) seed.Methods: Adult female Wistar rats(weight range: 120-150 g) were randomly divided into 4 and 5 treatment groups in the normal and triton-induced hyperlipidemic models, respectively. and were daily treated for 14 d before they were humanely sacrificed under inhaled diethyl ether anesthesia. About 5 mL of whole blood was obtained by cardiac puncture from each treated rat, from which serum for lipids assay was subsequently separated. Tissue samples of livers of treated rats were harvested and processed for histopathological analysis.Results: Repeated daily oral treatments of normal rats with 25 and 50 mg/kg/day of alkaloid fraction of H. umbellata resulted in significant(P<0.05 and P<0.001) and dose-dependent weight loss, and decreases in the serum triglyceride, total cholesterol and low density lipoprotein cholesterol, while significantly(P<0.001) increased the serum levels of high density lipoprotein cholesterol fraction. Similarly, oral pre-treatments with 25 and 50 mg/kg/day of alkaloid fraction of H. umbellata for 14 d before induction of hyperlipidemia with triton WR-1339 significantly(P<0.01, P<0.001) and dose-dependently attenuated increases in the average body weights, serum levels of triglyceride, total cholesterol and low density lipoprotein cholesterol while also significantly(P<0.01, P<0.001) and dose-dependently attenuated significant(P<0.001) decrease in the serum high-density lipoproteincholesterol levels when compared to the untreated control values. However, the results obtained for 50 mg/kg of alkaloid fraction of H. umbellata in both normal and triton WR-1339-induced hyperlipidemic rats were comparable to that recorded for 20 mg/kg of simvastatin. Similarly, oral pretreatments with 25 and 50 mg/kg/day of alkaloid fraction of H. umbellata significantly improved the histological lesions of fatty hepatic degeneration induced by triton WR-1339 treatment.Conclusions: Overall, results of this study showed that repeated oral treatments with 25 and 50 mg/kg/day of alkaloid fraction of H. umbellata elicited weight losing, antihyperlipidemic and cardioprotective effects in triton WR-1339 induced hyperlipidemic rats that were mediated via de novo cholesterol biosynthesis inhibition. | Adejuwon Adewale Adeneye Peter Anthony Crooks | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，5： | 0 |
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