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| 1 | β5整合素在造血细胞上的表达和诱导细胞凋亡的作用显示文摘目的 研究整合素 (integrins)αvβ5对造血细胞功能的影响。 方法 用逆转录病毒载体系统将αv、β5基因转染K5 6 2细胞 ,观察αv、β5亚基的表达 ;用去除血清的方法 ,观察造血细胞凋亡和分化时αvβ5和αvβ3的变化 ;用抗αvβ5单抗屏蔽造血细胞上αvβ5时对凋亡和增殖的影响。 结果 将含有 β5基因的逆转录病毒导入K5 6 2细胞 ,β5亚基没有得到表达 ;诱导造血细胞分化和凋亡时 ,αvβ5表达升高 ,而αvβ3表达下降 ;用单抗封闭细胞表面的αvβ5 ,可抑制去血清诱导的细胞凋亡。 结论 造血细胞αvβ5的过度表达可抑制细胞增殖并与细胞凋亡有关。 | 殷莲华 赵新永 付四清 F Garacia-Sanchez AB Deisseroth | 2001 | 中华血液学杂志2001，22，1： | 3 |
| 2 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 3 | Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community based study显示文摘 | Nieto F J Young TB Lind BK Shahar E Samet JM Redline S D’ Agostino RB Newman AB Lebowitz MD Picketing TG | 2000 | JAMA2000，283，： | 1 |
| 4 | Comparison of different culture media and growth conditions for recogrdtion of Arcanobacterium hacmolyticum 显示文摘 | Garcia-de-la-Fuente C Campo-Esquisabel AB Unda F | 2008 | Diagn Microbiol Infect Dis2008，61，2： | 1 |
| 5 | Use of safety-modified reroviruses to introduce chemotherapy resistance sequences into normal hematopoietic cells for chemoprotection during the therapy of breast cancer:a pilot trial显示文摘 | Deisseroth AB Holmes F Hortobagyi G | 1996 | Hum Gene Ther1996，7，3： | 1 |
| 6 | Intrastriatal injection of and adenoviral vector expressing glial cell line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease显示文摘 | Bleuel AB Revah F Colin P | 1997 | Proc Natl Acad Sci USA1997，94，16： | 1 |
| 7 | Determinants of BMI in patients with C OPD 显示文摘 | Karadag F Karul AB Cildag O | 2004 | Eur J Med Res2004，9，： | 1 |
| 8 | Cell penetrating peptides: overview and applications to the delivery of oli- onucleotides显示文摘 | Said hassane F Saleh AF Abes R | 2010 | Cell Mol Life Sci2010，67，5： | 1 |
| 9 | Split-calvariacsteoplastic rotational flap for anterior fossa floor repair after fumor excision显示文摘 | Kantrowitz AB Hall C Mosey F | 1993 | Neurosurg1993，79，5： | 1 |
| 10 | The job demands-resources model of burnout 显示文摘 | Demerouti E Bakker AB Nachreiner F | 2001 | J Appl Psychol2001，86，3： | 1 |
| 11 | Tuberculosis in diabetic patients in Tanzania显示文摘 | Swai AB McLarty DG Mugusi F | 1990 | Trop Doct1990，20，： | 1 |
| 12 | Pemistent cough in children:overnsc of medications显示文摘 | Thomson F Mastem IB Chang AB | 2002 | Paediatr Child Heal2002，38，： | 1 |
| 13 | Persistent cough in children:overuse of medications显示文摘 | Thomoson F Master IB Chang AB | 2002 | J Paediatr Child Health2002，38，： | 1 |
| 14 | Effect of atorvastatin on hematologic parameters in patients with hypercholesterolemia显示文摘 | Akin F AyaB Kse N | 2013 | Angiology2013，64，8： | 1 |
| 15 | Functional substrate biodiversity of cultivated and uncultivated Ahorizons of vertisols in New South Wales显示文摘 | Yan F McBratney AB | 2000 | Geoderma2000，96，： | 1 |
| 16 | Primary lymphoepithelioma- like carcinoma of the urinary bladder: report of one ease with review and update of the literature after a pooled analysis of 43 patients显示文摘 | Porcaro AB Gilioli E Migliorini F | 2003 | Int Urol Nephrol2003，35，1： | 1 |
| 17 | Increased prevalence of diabetes mellitus in patients with pulmonary tuberculosis in Tanzanis显示文摘 | Mugusi F Swai AB Alberti KG | 1990 | Tubercle1990，71，4： | 1 |
| 18 | Risk of revision of a total hip replacement in patients with diabetes melli- tus: a population-based follow up study 显示文摘 | Pedersen AB Mehnert F Johnsen SP | 2010 | J Bone Joint Surg ( Br)2010，92，7： | 1 |
| 19 | Correlates of non-thyroidal illness syndrome in chronic obstructive pulmonary disease 显示文摘 | Karadag F Ozcan H Karul AB | 2007 | Respir Med2007，101，7： | 1 |
| 20 | Correlates of non- thyroidal illness syndrome in chronic obstructives pulmonary disease 显示文摘 | Karadag F Ozcan H Karul AB | 2007 | Respir Med2007，101，7： | 1 |
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