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| 1 | Systematic review and meta-analysis on the association of tuberculosis in Crohn's disease patients treated with tumor necrosis factor-α inhibitors(Anti-TNFα)显示文摘AIM To perform a meta-analysis on the risk of developing Mycobacterium tuberculosis(TB) infection in Crohn's disease(CD) patients treated with tumor necrosis factoralpha(TNFα) inhibitors.METHODS A meta-analysis of randomized, double-blind, placebocontrolled trials of TNFα inhibitors for treatment of CD in adults was conducted. Arcsine transformation of TB incidence was performed to estimate risk difference. A novel epidemiologically-based correction(EBC) enabling inclusions of studies reporting no TB infection cases in placebo and treatment groups was developed to estimate relative odds.RESULTS Twenty-three clinical trial studies were identified, including 5669 patients. Six TB infection cases were reported across 5 studies, all from patients receiving TNFα inhibitors. Eighteen studies reported no TB infection cases in placebo and TNFα inhibitor treatment arms. TB infection risk was significantly increased among patients receiving TNFα inhibitors, with a risk difference of 0.028(95%CI: 0.0011-0.055). The odds ratio was 4.85(95%CI: 1.02-22.99) with EBC and 5.85(95%CI: 1.13-30.38) without EBC.CONCLUSION The risk of TB infection is higher among CD patients receiving TNFα inhibitors. Understanding the immunopathogenesis of CD is crucial, since using TNFα inhibitors in these patients could favor mycobacterial infections, particularly Mycobacterium avium subspecies paratuberculosis, which ultimately could worsen their clinical condition. | Brent L Cao Ahmad Qasem Robert C Sharp Latifa S Abdelli Saleh A Naser | 2018 | World Journal of Gastroenterology2018,24,25: | 4 |
| 2 | Kinetics of the Anti-oxidant Response to Salinity in the Halophyte Cakile maritima显示文摘在抗氧化剂酶(超级氧化物 dismutase ,过氧化氢酶(猫),过氧化物酶(邮政部门), ascorbate 过氧化物酶( APX ), monodehydroascorbate reductase , dehydroascorbate reductase ( DHAR ),和 glutathionereductase ( GR ))的活动的 NaCI 应力的效果,抗氧化剂分子( ascorbate 和谷胱甘肽),并且氧化应力( malondialdehyde ( MDA ),电解质漏,和 H_2O_2 集中)的参数在 Cakilemaritima 被调查,沿着突尼斯的海岸经常的盐土植物。幼苗面对盐(100, 200,和 400 mmol/L NaCI ) 被种。植物在 20 天周期性地被收获。生长面对 0-100 mmol/L NaCI 是最大的。在 400 mmol/L NaCI,生长显著地减少了。C 的 Thesalt 忍耐。在中等咸度, maritima 与氧化应力的最低价值 oftheparameters 陈述语气被联系,也就是,邮政部门,猫, APX, DHAR, andGR 和高织物的最高的活动 ascorbate 和谷胱甘肽满足。然而,延长了暴露到高咸度在 anti-oxidantactivities 和高 MDA 导致了减少内容,电解质漏,和 H_2O_2 集中。这些结果建议 anti-oxidantsystems 参予 C 的忍耐。maritima 将节制咸度。 | Nader Ben Amor Ana Jimenez Wided Megdiche Marianne Lundqvist Francisca Sevilla Chedly Abdelly | 2007 | Journal of Integrative Plant Biology2007,49,7: | 2 |
| 3 | The c - Jun N - terminal kinase JNK participates in cytokine and isolation stress - induced ratpanre - a mtic islet apoptosis 显示文摘 | Abdelli S Abderrahmani A Hering B J | 2007 | Diabetologia2007,50,: | 1 |
| 4 | Gastric emptying is accelerated in obese type 2 diabetic patients without autonomic neuropathy 显示文摘 | Bertin E Schneider N Abdelli N | 2001 | Diabetes Metab2001,27,3: | 1 |
| 5 | Comparison of toxicities from three metal oxide nanoparticles at environmental relevant concentrations in nematode Caenorhabditis elegans 显示文摘 | Qiuli W Abdelli N Yiping L | 2012 | Chemosphere2012,90,3: | 1 |
| 6 | Phytodesalination of a salt-affected soil with the halophyte Sesuvium portulacastrum L. to arrange in advance the requirements for the successful growth of a glycophytic crop显示文摘 | Mokded Rabhi Siwar Ferchichi Jihène Jouini Mohamed Hédi Hamrouni Hans-Werner Koyro Annamaria Ranieri Chedly Abdelly Abderrazak Smaoui | 2010 | Bioresource Technology2010,,17: | 1 |
| 7 | Salt tolerance of the annual halophyte Cakile maritima as affected by the provenance and the developmental stage显示文摘 | Megdiche W Ahmed N B Debez A Hessini K Ksouri R Zuily-Fodil Y Abdelly C | 2007 | Acta Physiologiae Plantarum2007,29,4: | 1 |
| 8 | Performancesimprovements and torque ripple minimization for VSI fed induction machine with direct control torque 显示文摘 | Abdelli R Rekioua D Rekioua T | 2011 | ISA Transactions2011,50,: | 1 |
| 9 | Modelling water-harvesting systems in the arid south of Tunisia using SWAT显示文摘 | Ouessar M Bruggeman A Abdelli F | 2009 | Hydrology and Earth System Sciences2009,13,10: | 1 |
| 10 | Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the e-Jun NH2-terminal kinase pathway显示文摘 | Ferdaoussi M Abdelli S Yang JY | 2008 | Diabetes2008,57,5: | 1 |
| 11 | Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway显示文摘 | Ferdaoussi M Abdelli S Yang JY | 2008 | Diabetes2008,57,5: | 1 |
| 12 | LC–ESI-TOF–MS identification of bioactive secondary metabolites involved in the antioxidant, anti-inflammatory and anticancer activities of the edible halophyte Zygophyllum album Desf.显示文摘 | Wided Megdiche Ksouri Faten Medini Khaoula Mkadmini Jean Legault Christian Magné Chedly Abdelly Riadh Ksouri | 2013 | Food Chemistry . 2013 (1-4)2013,,1: | 1 |
| 13 | Percutaneous MR-guided cryoablation of prostate cancer:initial experience显示文摘 | Gangi A Tsoumakidou G Abdelli O | 2012 | Eur Radiol2012,22,8: | 1 |
| 14 | Effects of salt on lipid peroxidation and antioxidant enzyme activities of Catharanthus roseus suspension cells 显示文摘 | Elkahoui S Hernandez J A Abdelly C | 2005 | Plant Sci- ence2005,168,3: | 1 |
| 15 | Transplanted inducedpluripo tent stem cell improve cardiac function and induce neovascular ization in the infarcted hearts of db/db mice显示文摘 | Yan B Abdelli LS Singla DK | 2011 | Mol Pharm2011,8,5: | 1 |
| 16 | Exendin-4 protects betacells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway显示文摘 | Ferdaoussi M Abdelli S Yang JY | 2008 | Diabetes2008,57,: | 1 |
| 17 | Exendin-4 protects beta- cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway 显示文摘 | Ferdaoussi M Abdelli S Yang JY | 2008 | Diabetes2008,57,5: | 1 |
| 18 | Effect of salinity on root-nodule conductance to the oxygen diffusion in the (Medicago truncat- ula) - (Sinorhizobium rneliloti) symbiosis显示文摘 | Aydi S Drevon J J Abdelly C | 2004 | Plant Physiology and Biochemistry2004,42,10: | 1 |
| 19 | Percutaneous MR-guided cryoablation of prostate cancer: initial experi?ence显示文摘 | Gangi A Tsoumakidou G Abdelli 0 | 2012 | Eur Radiol2012,22,8: | 1 |
| 20 | Uranium isotopes in Tunisian bottled mineral waters显示文摘 | Gharbi F Baccouche S Abdelli W ct al | 2010 | J Environ Radioact2010,101,: | 1 |