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| 1 | Inflammatory status in chronic renal failure: The role of homocysteinemia and pro-inflammatory cytokines显示文摘AIM: To evaluate determinants of inflammatory markers in chronic renal failure patients according to the level of glomerular filtration rate. METHODS: One hundred fifty four patients(Age; 44 ± 06 years, male/female; 66/88) with chronic renal failure(CRF) were divided into 6 groups according to the National Kidney Foundation(NKF) classification. They included 28 primary stage renal failure patients(CRF 1), 28 moderate stage renal failure patients(CRF 2),28 severe stage renal failure patients(CRF 3), 18 endstage renal failure patients(CRF 4), 40 hemodialysis(HD) patients, and 12 peritoneal dialysis(PD) patients. Tumor necrosis factor-α(TNF-α), interleukin-1β(IL-1β), interleukin-6(IL-6) and C-reactive protein(CRP) were analyzed by immunosorbent assay kit(ELISA)(Cayman Chemical's ACETM EIA kit). Immunoassay methods were used for total homocysteine(tH cy)(fluorescence polarization immunoanalysis HPLC, Perkin Emer 200 series), transferrin(MININEPHTM human transferin kit: ZK070.R), ferritin(ADVIA Centaur) and fibrinogen analysis(ACL 200). Differences between groups were performed using SPSS 20.0 and data are expressed as the mean ± SD.RESULTS: Results showed that in comparison with CRF 1 group and other groups, TNF-α and IL-6 levels were respectively more elevated in HD(16.38 ± 5.52 pg/mL vs 0.39 ± 0.03 pg/mL, 11.05 ± 3.59 pg/mL vs 8.20 ± 0.22 pg/mL, P < 0.001) and PD(14.04 ± 3.40 pg/m L vs 0.39 ± 0.03 pg/m L, 10.15 ± 1.66 pg/m L vs 8.20 ± 0.22 pg/m L, P < 0.001). IL-1β levels were increased in HD(9.63 ± 3.50 pg/m L vs 3.24 ± 0.10 pg/mL, P < 0.001) and CRF 4(7.76 ± 0.66 pg/mL vs 3.24 ± 0.10 pg/m L, P < 0.001) patients than in CRF 1 and in the other groups. Plasma t Hcy levels were higher in HD(32.27 ± 12.08 μmol/L) and PD(28.37 ± 4.98 μmol/L) patients compared to the other groups of CRF(P < 0.001). The serum CRP level was significantly increased in HD(18.17 ± 6.38 mg/L) and PD(17.97 ± 4.85 mg/L) patients compared to the other groups of CRF patients(P < 0.001). The plasma fibrinogen level was more elevated in HD(6.86 ± 1.06 g/L) and CRF 4(6.05 ± 0.57 g/L) than in the other groups(P < 0.001). Furthermore; the ferritin level was higher in HD(169.90 ± 62.16 ng/m L) and PD(90.08 ± 22.09 ng/m L) patients compared to the other groups of CRF(P < 0.001). The serum transferrin value was significantly decreased especially in PD(1.78 ± 0.21 g/L) compared to the other groups(P < 0.001). We found a negative correlationbetween glomerular filtration rate(GFR), TNF-α levels(r =-0.75, P < 0.001), and t Hcy levels(r =-0.68, P < 0.001). We observed a positive correlation between GFR and transferrin levels(r = 0.60, P < 0.001). CONCLUSION: CRF was associated with elevated inflammatory markers. The inflammation was observed at the severe stage of CRF and increases with progression of renal failure. | Hadja Fatima Tbahriti Djamel Meknassi Rachid Moussaoui Amar Messaoudi Lakhdar Zemour Abbou Kaddous Malika Bouchenak Khedidja Mekki | 2013 | World Journal of Nephrology2013，2，2： | 32 |
| 2 | 腹膜外径路腹腔镜前列腺癌根治术(附65例报告)显示文摘目的:探讨腹膜外径路腹腔镜PCa根治术的初步体会。方法:经腹膜外径路进行腹腔镜PCa根治术65例。结果:64例(98.5%)成功,手术时间100~440min,平均172min。出血量150~800ml,平均340ml,7例(10.8%)患者输红细胞悬液2~4U。1例术中发生直肠损伤,2例术后发生尿外渗。6例(9.2%)患者术后病理提示切缘阳性。58例(89.2%)患者术后3个月尿控良好。结论:腹膜外径路腹腔镜PCa根治术是安全、可行的。且因避免了术中、术后对腹腔内肠管的干扰,降低了手术并发症,利于术后患者的恢复,值得在临床推广应用。 | 薛波新 单玉喜 ABBOU CC | 2007 | 中华男科学杂志2007，13，11： | 9 |
| 3 | 腹腔镜模拟训练箱内采用连续法、双半圆法行膀胱—尿道吻合术的评价显示文摘目的评价腹腔镜模拟训练箱内分别采用连续法、双半圆法行膀胱-尿道吻合术的成效及各自的优缺点。方法腹腔镜模拟训练箱内,利用膀胱-尿道模型,分别采用连续法、双半圆法行膀胱-尿道吻合术。缝线均为Vicryl3-0可吸收线。连续法──从3点顺时针连续缝合10~12针至3点;双半圆法──从6点顺时针连续缝合5、6针至12点,再从6点逆时针连续缝合5、6针至12点。以没有漏针、边缘撕脱及吻合口能自由通过18F导尿管作为吻合术成功的标准。记录每次手术时间,分别描记各组的学习曲线。比较两种吻合方式的优劣。结果该组采用连续法、双半圆法行膀胱-尿道吻合术各21例,吻合口均符合标准。连续法吻合时间26~60min,平均(37.91±1.98)min,双半圆法吻合时间24~62min,平均(33.95±2.23)min。两组手术时间比较差异有显著性(P<0.001)。通过比较手术时间、吻合口质量、手术难易度等发现双半圆法优于连续法。结论成功应用模型在腹腔镜模拟训练箱内行膀胱-尿道吻合术,进一步拓展了腹腔镜模拟训练的训练深度。通过体外模拟训练,评价两种吻合方式的优劣,有助于临床实践中手术步骤的改进。 | 薛波新 单玉喜 Clement-Claude ABBOU | 2008 | 中国内镜杂志2008，14，8： | 2 |
| 4 | SAFETY AND EFFICACY OF PARTIAL NEPHRECTOMY FOR ALL T1 TUMORS BASED ON AN INTERNATIONAL MULTICENTER EXPERIENCE显示文摘 | JEAN-JACQUES PATARD OLEG SHVARTS JOHN S. LAM ALLAN J. PANTUCK HYUNG L. KIM VINCENZO FICARRA LUCA CINDOLO KEN-RYU HAN ALEXANDRE DE LA TAILLE JACQUES TOSTAIN WALTER ARTIBANI CLAUDE C. ABBOU BERNARD LOBEL DOMINIQUE K. CHOPIN ROBERT A. FIGLIN PETER F.A. MULDE | 2004 | The Journal of Urology2004，，6： | 2 |
| 5 | EAU guidelines on prostate cancer显示文摘 | Aus G Abbou CC Pacik D et ol | 2001 | Eur Urol2001，40，： | 1 |
| 6 | Orchiectomy and nilutamide or placebo as treatment of metastatic prostatic cancer in a multinational double-blind randomized trial显示文摘 | Janknegt RA Abbou CC Bartoletti R | 1993 | Urol1993，149，： | 1 |
| 7 | The learning curve for lapa- roscopic radical prostatectomy: an international multicenter study 显示文摘 | Secin FP Savage C Abbou C | 2010 | J Urol2010，184，6： | 1 |
| 8 | Remote laparoscopic radical prostatectomy carried out with a robot: report of a case显示文摘 | Abbou CC Hoznek A Salomon L | 2000 | Prog Urol2000，10，4： | 1 |
| 9 | EAU Guidelines on Prostate Canc- er显示文摘 | Aus G Abbou CC Bolla M | 2005 | Euro Uro12005，48，： | 1 |
| 10 | T HELPER 1/2 LYMPHOCYTE URINARY CYTOKINE PROFILES IN RESPONDING AND NONRESPONDING PATIENTS AFTER 1 AND 2 COURSES OF BACILLUS CALMETTE-GUERIN FOR SUPERFICIAL BLADDER CANCER显示文摘 | FABIEN SAINT JEAN J. PATARD PASCALE MAILLE PASCALE SOYEUX ANDRé HOZNEK LAURENT SALOMON ALEXANDRE DE LA TAILLE CLAUDE C. ABBOU DOMINIQUE K. CHOPIN | 2001 | The Journal of Urology2001，，6： | 1 |
| 11 | EAU guidelines on prostate cancer显示文摘 | Aus G Abbou CC Bollam | 2005 | Eur Urol2005，48，4： | 1 |
| 12 | Orchiectomy and nilutamide or placebo as treatment of metastatic prostatic cancer in a multinational double blind randomized trial显示文摘 | Janknegt RA Abbou CC Bartoletti R | 1993 | J Urol1993，149，1： | 1 |
| 13 | Sensor-less speed control of induction motor using DTFC based fuzzy logic显示文摘 | ABBOU A MAHMOUDI H | 2008 | Journal of Electrical Engineering2008，2，5： | 1 |
| 14 | Influence of urological complications on the prognosis of prostatic cancer显示文摘 | Colombel M Mallame W Abbou CC | 1997 | Eur Urol1997，31，3： | 1 |
| 15 | PROGNOSTIC VALUE OF A T HELPER 1 URINARY CYTOKINE RESPONSE AFTER INTRAVESICAL BACILLUS CALMETTE-GUERIN TREATMENT FOR SUPERFICIAL BLADDER CANCER显示文摘 | FABIEN SAINT JEAN J. PATARD PASCALE MAILLE PASCALE SOYEUX ANDRé HOZNEK LAURENT SALOMON CLAUDE C. ABBOU DOMINIQUE K. CHOPIN | 2002 | The Journal of Urology2002，，1： | 1 |
| 16 | EAU guidelines on prostate cancer显示文摘 | Aus G Abbou CC Bolla M etal | 2005 | Eur Urol2005，48，4： | 1 |
| 17 | Laparoscopic partial nephrectomy:the european experience显示文摘 | Rassweiler JJ Abbou C Janetschek G | 2009 | Urol Clin North Am2009，27，： | 1 |
| 18 | Laparoscopic radical prostatectomy: preliminary results显示文摘 | Abbou CC Salomon L Hoznek A | 2000 | Urology2000，55，： | 1 |
| 19 | Frequent germ-line succinate dchydrogenase subunit D gene mutations in patients with apparendy sporadic parasympathetic paragangiioma显示文摘 | Dannenberg H Dinjens WN Abbou M | 2002 | Clin Cancer Res2002，8，7： | 1 |
| 20 | Laparoscopic radical prostatectomy:preliminary results显示文摘 | Abbou C C Salomon L Hoznek A | 2000 | Urology2000，55，： | 1 |
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