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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Post-punching behavior of flat slabs显示文摘 | Miguel F R Yaser M Aurelio M | 2013 | ACI Structural Journal2013，，80： | 1 |
| 3 | Role of mirochondria in oxidative stress and aging显示文摘 | Lenaz G Bovina C D'Aurelio M | 2002 | Ann N Y Acad Sci2002，959，： | 1 |
| 4 | Philippine Fault: a key for Philippine kinematics 显示文摘 | Barrier B Huchon P Aurelio M | 1991 | Geology1991，，1： | 1 |
| 5 | Estimating microbial population counts by 'most probable number' using Microsoft Excel显示文摘 | AURELIO M BRIONES J REICHARDT W | 1999 | J Microb Methods1999，35，： | 1 |
| 6 | A comparative study between two nonlinear control techniques for induction motor drives显示文摘 | JOSE D M F AURELIO G C | 2002 | IEEE2002，，6： | 1 |
| 7 | Fruoplocamioids A-C,novel polyhalogenated furanoid monoterpenes from Plocamium cartilagineum显示文摘 | Jose D Juana R Aurelio S M | 2001 | J Nat Prod2001，64，4： | 1 |
| 8 | Hysterosalpingocontrast sonography (HyCoSy): evaluation of the pain perception, side effects and complications显示文摘 | Roberto M Immacolata M Aurelio A | 2013 | BMC Medical Imaging2013，13，： | 1 |
| 9 | Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic pupura显示文摘 | DONALD M A ISHAC N AURELIO S | | 0，，08： | 1 |
| 10 | Reducing the formation of trihalomethanes (THMs) by ozone combined with hydrogen peroxide (H2O2 /O3) 显示文摘 | Mohammad A A Aurelio H M | 2006 | Desalination2006，194，13： | 1 |
| 11 | Bioenergetics of mitochondrial diseases associated with mtDNA mutations 显示文摘 | Lenaz G Baracca A Carelli V D'Aurelio M Sgarbi G Solaini G | 2004 | Biochim Biophys Acta2004，1658，12： | 1 |
| 12 | Ammonia-oxidizing bacteria on root biofilms and their possible contribution to N use efficiency of different rice cultivars显示文摘 | Aurelio M Briones J Satoshi O | 2003 | Plant and Soil2003，250，： | 1 |
| 13 | Plasma membrane oxidoreductase activity in cultured cells in relation to mitochondrial function and oxidative stress显示文摘 | Deleonardi G Biondi A D'Aurelio M | 2004 | Biofactors2004，20，4： | 1 |
| 14 | p53-mediated negative regulation of stathmin/Op 18 expression is associated with G2/M cell-cycle arrest显示文摘 | JOHNSEN J I AURELIO O M N KWAJA Z | 2000 | Int J Cancer2000，88，5： | 1 |
| 15 | Ammonia-oxidizing bacteria on root biofilms and their possible contribution to N use efficiency of different rice cultivars显示文摘 | Aurelio M Briones J Okabe S | 2003 | Plant and Soil2003，250，： | 1 |
| 16 | Heterologous mitochondrial DNA recombination in human cells显示文摘 | Gajewski CD Lin MT | 2004 | Hum Mol Genet2004，13，24： | 1 |
| 17 | Heterologous mitochondrial DNA recombination in human cells显示文摘 | D' Aurelio M Gajewski CD Lin MT | 2004 | Hum Mol Genet2004，13，： | 1 |
| 18 | Aspergillus flavus doseresponse curves to selected natural and synthetic antimicrobials 显示文摘 | Aurelio Lo' pez- Malo Stella M Alzamora Enrique Palou | 2002 | International Journal of Food Microbiology2002，73，： | 1 |
| 19 | Optimizing conditions for the extraction of pigments in cochineals (Dactylopius coccus Costa) using response surface methodology显示文摘 | MONICA G JESUS M AURELIO C | 2002 | Journal of Agricultural and Food Chemistry2002，50，24： | 1 |
| 20 | An assembled complex Ⅳ maintains the stability and activity of complex Ⅰ in mammalian mitochondria显示文摘 | Li Y D'Aurelio M Deng JH | 2007 | J Biol Chem2007，282，17： | 1 |
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