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| 1 | Recently duplicated sesterterpene(C25) gene clusters in Arabidopsis thaliana modulate root microbiota显示文摘Land plants co-speciate with a diversity of continually expanding plant specialized metabolites(PSMs) and root microbial communities(microbiota).Homeostatic interactions between plants and root microbiota are essential for plant survival in natural environments.A growing appreciation of microbiota for plant health is fuelling rapid advances in genetic mechanisms of controlling microbiota by host plants.PSMs have long been proposed to mediate plant and single microbe interactions.However,the effects of PSMs,especially those evolutionarily new PSMs,on root microbiota at community level remain to be elucidated.Here,we discovered sesterterpenes in Arabidopsis thaliana,produced by recently duplicated prenyltransferase-terpene synthase(PT-TPS) gene clusters,with neo-functionalization.A single-residue substitution played a critical role in the acquisition of sesterterpene synthase(sesterTPS) activity in Brassicaceae plants.Moreover,we found that the absence of two root-specific sesterterpenoids,with similar chemical structure,significantly affected root microbiota assembly in similar patterns.Our results not only demonstrate the sensitivity of plant microbiota to PSMs but also establish a complete framework of host plants to control root microbiota composition through evolutionarily dynamic PSMs. | Qingwen Chen Ting Jiang Yong-Xin Liu Haili Liu Tao Zhao Zhixi Liu Xiangchao Gan Asis Hallab Xuemei Wang Juan He Yihua Ma Fengxia Zhang Tao Jin M. Eric Schranz Yong Wang Yang Bai Guodong Wang | 2019 | Science China(Life Sciences)2019，62，7： | 11 |
| 2 | 反相高效液相色谱法测定有机氯及含氮杀虫剂在水体·土壤沉积物及鱼体中的残留(摘要)(英文)显示文摘[目的]测定水体、土壤沉积物以及鱼体内有机氯及含氮杀虫剂残留物,为科学评估杀虫剂残留对巴基斯坦地区公共卫生、农业和环境的影响提供依据。[方法]以食用鱼南亚野鲮为材料,设计2组体重,采用高效液相色谱法分别测定水体、土壤沉积物以及南亚野鲮体内α-硫丹、DDE、甲基对硫磷、异丙隆、呋喃丹、阿特拉津等含量。[结果]土壤沉积物中DDE的含量达(2.340±0.025)μg/g,在250 ~750 g的南亚野鲮体内的含量分别为(0.270 ±0.000 6)μg/g,但在水体中未发现DDE残留;不同饲料中农药残留物90%为有机磷、呋喃丹以及有机氯杀虫剂,6%为杀菌剂,仅4%为除草剂,在250 ~750 g以及800 ~1 300 g的南亚野鲮体内硫丹的含量分别达到(0.491±0.000 6)μg/g和(3.050±0.060 8)μg/g,异丙隆的含量分别达到(0.010±0.0003)μg/g和(0.014±0.000 6)μg/g,且随体重上升,其脂肪含量增加,积累的农药残留物则越多;硫丹、甲基对硫磷、阿特拉津和呋喃丹的含量在水体达到最大残留限量水平0.001μg/g。[结论]通过生物积累和在自然界中的运输以及再沉积作用,有机氯及其他杀虫剂的使用给全球的环境造成了严重污染,因此,在巴基斯坦已经禁止使用DDT等有机氯农药。 | Shahid Mahboob Ghazala S.Sultana Muhammad Rafique Asi S.Nadeem A.S.Chaudhry | 2009 | Agricultural Science & Technology2009，10，5： | 9 |
| 3 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 4 | Circulation characteristics of horseshoe vortex in scour region around circular piers显示文摘This paper presents an experimental investigation of the circulation of the horseshoe vortex system within the equilibrium scour hole at a circular pier, with the data measured by an acoustic Doppler velocimeter (ADV). Velocity vector plots and vorticity contours of the flow field on the upstream plane of symmetry (y = 0 cm) and on the planes ±3 cm away from the plane of symmetry (y = ±3 cm) are presented. The vorticity and circulation of the horseshoe vortices were determined using the forward difference technique and Stokes theorem, respectively. The results show that the magnitudes of circulations are similar on the planes y = 3 cm and y = -3 cm, which are less than those on the plane y = 0 cm. The circulation decreases with the increase of flow shallowness, and increases with the densimetric Froude number. It also increases with the pier Reynolds number at a constant densimetric Froude number, or at a constant flow shallowness. The relative vortex strength (dimensionless circulation) decreases with the increase of the pier Reynolds number. Some empirical equations are proposed based on the results. The predicted circulation values with these equations match the measured data, which indicates that these equations can be used to estimate the circulation in future studies. | Subhasish DAS Rajib DAS Asis MAZUMDAR | 2013 | Water Science and Engineering2013，6，1： | 2 |
| 5 | MapMan4: A Refined Protein Classification and Annotation Framework Applicable to Multi-Omics Data Analysis显示文摘Genome sequences from over 200 plant species have already been published, with this number expected to increase rapidly due to advances in sequencing technologies. Once a new genome has been assembled and the genes identified, the functional annotation of their putative translational products, proteins, using ontologies is of key importance as it places the sequencing data in a biological context. Furthermore, to keep pace with rapid production of genome sequences, this functional annotation process must be fully automated. Here we present a redesigned and significantly enhanced MapMan4 framework, together with a revised version of the associated online Mercator annotation tool. Compared with the original MapMan, the new ontology has been expanded almost threefold and enforces stricter assignment rules. This framework was then incorporated into Mercator4, which has been upgraded to reflect current knowledge across the land plant group, providing protein annotations for all embryophytes with a comparably high quality. The annotation process has been optimized to allow a plant genome to be annotated in a matter of minutes. The output results continue to be compatible with the established MapMan desktop application. | Rainer Schwacke Gabriel Y.Ponce-Soto Kirsten Krause Anthony M.Bolger Borjana Arsova Asis Hallab Kristina Gruden Mark Stitt Marie E.Bolger Bjorn Usadel | 2019 | Molecular Plant2019，12，6： | 2 |
| 6 | Neosporosis: An Overview of Its Molecular Epidemiology and Pathogenesis显示文摘Neospora caninum (N. caninum), a cyst-forming protozoan parasite, is a major cause of bovine abortions and neonatal mortality worldwide. N. caninum has a broad intermediate host range, and its sexual cycle occurs exclusively in canids. Another species of Neospora, Neospora hughesi (N. hughesi), has been identified and causes myeloencephalitis in horses. Although molecular epidemiology studies are in their infancy, the 18S ribosomal RNA (rRNA) and ITS1 regions within the small subunit ribosomal RNA (ssuRNA) and an N. caninum species-specific DNA probe (pNc5) have been used extensively to differentiate Neospora from other closely related apicomplexan parasites. While these repetitive regions have higher sensitivity and specificity than housekeeping or antigen genes, they suffer from low discriminatory power and fail to capture intra-species diversity. Similarly, although multiple minisatellite or microsatellite marker studies have shown clear geographic substructures within Neospora, strains are often misclassified due to a convergence in the size of different alleles at microsatellite loci, known as homoplasy. Only one strain, N. caninum Liverpool (Nc-Liv), has been genome sequenced and compared with its closest relative, Toxoplasma gondii (T. gondii). Hence, detailed population genomics studies based on whole-genome sequences from multiple strains worldwide are needed in order to better understand the current population genetic structure of Neospora, and ultimately to determine more effective vaccine candidates against bovine neosporosis. The aim of this review is to outline our current understanding of the molecular epidemiology and genomics of Neospora in juxtaposition with the closely related apicomplexan parasites Hammondia hammondi and T. gondii. | Asis Khan Jahangheer S.Shaik Patricia Sikorski Jitender P.Dubey Michael E.Grigg | 2020 | Engineering2020，6，1： | 2 |
| 7 | Fatigue failure of a helical gear in gearbox显示文摘 | ASI O | 2006 | Engineering Failure Analysis2006，13，7： | 1 |
| 8 | Genetic dissection of vitamin E biosynthesis in tomato 显示文摘 | Almeida J Quadrana L Asis R | 2011 | J Experimental Botany2011，62，： | 1 |
| 9 | Free radical scavenging activity of Castanopsis indica in mediating hepatoprotective activity of carbon tetrachloride intoxicated rats显示文摘 | Narayan Dolai Indrajit Karmakar RB Suresh Kumar Biswakanth Kar Asis Bala Pallab Kanti Haldar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，，1： | 1 |
| 10 | Estimation of vegetation parameter for modeling soil erosion using linear spectral mixture analysis of Landsat ETM data显示文摘 | De Asis A M Omasa K | | 0，，04： | 1 |
| 11 | Atrophy of the medial occipitotemporal,inferior,and middle temporal gyri in non-demented elderly predicts decline to Alzheimer's disease显示文摘 | Convit A Asis J Leon MJ | 2000 | Neurobiol Aging2000，21，1： | 1 |
| 12 | Assessment of aflatoxins,ochratoxin A and zearalenone in breakfast cereals显示文摘 | Iqbal S Z Rabbani T Asi M R Jinap S | 2014 | Food Chemistry2014，157，15： | 1 |
| 13 | Determination of aria- toxin B1 in highly contaminated peanut samples usingHPLC and ELISA 显示文摘 | Asis R Paola D Aldao J | 2002 | Food and Agricultural Immunolo- gy2002，14，： | 1 |
| 14 | Proportioning RCCP mixes under hot weather conditions for a specified tensile strength显示文摘 | QASRAWI H Y ASI I M WAHHABB H I | 2005 | Cement and Concrete Research2005，35，2： | 1 |
| 15 | The neuropathology, pathophysiology and genetics of multiple system atrophy 显示文摘 | Ahmed Z Asi YT Sailer A | 2012 | Neuropathol Appl Neurobiol2012，38，1： | 1 |
| 16 | Evaluating skid resistance of different as-phalt concrete mixes显示文摘 | ASI I M | 2007 | Building and Environment2007，42，1： | 1 |
| 17 | Hippocampal and anterior cingulated activation deficits in patients with geriatric de2 pression 显示文摘 | De Asis JM Stern E Alexopoulos GS | 2001 | Am J Psychiatry2001，158，1： | 1 |
| 18 | Emergence of scaling in random network 显示文摘 | BARB ASI | 1999 | Sc-cience1999，286，： | 1 |
| 19 | Aflatoxins contamination in peanut and peanut products commercially available in retail markets of Punjab,Pakistan显示文摘 | IQBAL S Z ASI M R ZUBER M | 2013 | Food Control2013，32，1： | 1 |
| 20 | Estimation of vegetation parameter for modeling soil erosion using linear Spectral Mixture Analysis of Landsat ETM data显示文摘 | De ASIS A M OMASA K | 2007 | Journal of Photogrammetry and Remote Sensing2007，62，4： | 1 |
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