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| 1 | Cardiovascular risk factors for acute stroke: Risk profiles in the different subtypes of ischemic stroke显示文摘Timely diagnosis and control of cardiovascular risk factors is a priority objective for adequate primary and secondary prevention of acute stroke. Hypertension, atrial fibrillation and diabetes mellitus are the most common risk factors for acute cerebrovascular events, although novel risk factors, such as sleep-disordered breathing, inflammatory markers or carotid intima-media thickness have been identified. However, the cardiovascular risk factors profile differs according to the different subtypes of ischemic stroke. Atrial fibrillation and ischemic heart disease are more frequent in patients with cardioembolic infarction, hypertension and diabetes in patients with lacunar stroke, and vascular peripheral disease, hypertension, diabetes, previous transient ischemic attack and chronic obstructive pulmonary disease in patients with atherothrombotic infarction. This review aims to present updated data on risk factors for acute ischemic stroke as well as to describe the usefulness of new and emerging vascular risk factors in stroke patients. | Adrià Arboix | 2015 | World Journal of Clinical Cases2015，3，5： | 29 |
| 2 | Stroke and sleep-disordered breathing: A relationship under construction显示文摘The association between sleep-disordered breathing(SDB) and cardiovascular risk has been the focus of attention in recent years.Sleep disorders are emerging risk factors for cardiovascular disease and have been related to the whole spectrum of stroke,including transient ischemic attack,ischemic cerebral infarction and intracerebral haemorrhage.It has been shown that lacunar stroke or lacunar infarctions affecting the internal capsule or the protuberance are associated with a higher frequency of SDB.Acute stroke patients with associated SDB have a worse prognosis and a higher mortality as compared to patients with first-ever stroke without SDB.Preliminary studies provide evidence of the usefulness of treatment with continuous positive airway pressure when SDB is present in stroke patients. | Olga Parra Adrià Arboix | 2016 | World Journal of Clinical Cases2016，4，2： | 5 |
| 3 | The role of small vessel disease in development of Alzheimer's disease显示文摘Classically Alzheimer's disease and vascular dementia have been considered as two different entities,with their own clinical criteria,but relatively recent epidemiological and clinicopathological studies suggest an overlap between them sharing not only most of the risk factors and some clinical aspects but also pathophysiological mechanisms.Cerebrovascular lesions,especially small vessel disease(lacunar infarcts,white matter hyperintensities and microbleeds),may magnify the effects of mild Alzheimer's disease pathology and promote the progression of cognitive decline and may also be a precursor of neuronal damage and dementia.'Vascular hypothesis' of Alzheimer's disease would open a window for new approaches and treatments. | Marta Grau-Slevin Adria Arboix John Gaffney Mark Slevin | 2010 | Neural Regeneration Research2010，5，4： | 4 |
| 4 | Cortical laminar necrosis related to migrainous cerebral infarction显示文摘We present a 29-year-old woman with a long history of attacks of migraine with and without visual aura.She was a heavy smoker(20 cigarettes/d) and was currently taking oral contraceptives. During a typical migraine attack with aura, she developed dysarthria,left brachial hemiparesis and hemihypoesthesia and brief and autolimited left clonic facial movements. Four hours after onset, vascular headache and focal sensorimotor neurological deficit were the only persisting symptoms and, on seventh day, she was completely recovered. Brain magnetic resonance imaging on day 20 after onset showed a subacute ischemic lesion in the right temporo-parietal cortex compatible with cortical laminar necrosis(CLN). Extensive neurological work-up done to rule out other known causes of cerebral infarct with CLN was unrevealing. Only ten of 3.808 consecutive stroke patients included in our stroke registry over a 19-year period fulfilled the strictly defined International Headache Society criteria for migrainous stroke. The present case is the unique one in our stroke registry that presents CLN related to migrainous cerebral infarction. Migrainous infarction can result in CLN. | Adrià Arboix Sebastià González-Peris Elisenda Grivé María-José Sánchez Emili Comes | 2013 | World Journal of Clinical Cases2013，1，8： | 4 |
| 5 | Bayés syndrome and acute cardioembolic ischemic stroke显示文摘Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial block.Bayés syndrome is a subclinical disease that manifests electrocardiographically as a prolonged P wave duration>120 ms with biphasic morphology±in the inferior leads.The clinical relevance of Bayés syndrome lies in the fact that is a clear arrhythmological syndrome and has a strong association with supraventricular arrhythmias,particularly atypical atrial flutter and atrial fibrillation.Likewise,Bayés syndrome has been recently identified as a novel risk factor for non-lacunar cardioembolic ischemic stroke and vascular dementia.Advanced interatrial block can be a risk for embolic stroke due to its known sequelae of left atrial dilation,left atrial electromechanical dysfunction or atrial tachyarrhythmia(paroxysmal or persistent atrial fibrillation),conditions predisposing to thromboembolism.Bayés syndrome may be responsible for some of the unexplained ischemic strokes and shall be considered and investigated as a possible cause for cryptogenetic stroke.In summary,Bayés syndrome is a poorly recognized cardiac rhythm disorder with important cardiologic and neurologic implications. | Adrià Arboix Lucía Martí Sebastien Dorison María José Sánchez | 2017 | World Journal of Clinical Cases2017，5，3： | 3 |
| 6 | Predictive clinical features of cardioembolic infarction in patients aged 85 years and older显示文摘Objective To assess predictive clinical factors of cardioembolic infarction in very old patients(85 years of age and older).Methods Prospective hospital-based stroke registry('The Sagrat Cor Hospital of Barcelona Stroke Registry')is an acute-care teaching hospital in Barcelona,Catalonia,Spain.From 956 first-ever cardioembolic stroke patients included in the stroke registry over a 24-year period,639 were younger than 85 years of age and 317 were 85 years or older(mean age:88.9 years).Demographics,clinical characteristics,risk factors and early outcome were compared.Predictors of cardioembolic infarction in the oldest age group were assessed by multivariate analyses.Results In a logistic regression model based on demographics,risk factors,clinical features and complications,female gender(odds ratio[OR]=1.74,95%confidence interval[CI]:1.27–2.39),heart failure(OR=2.27,95%CI:1.46–3.56),altered consciousness(OR=1.76,95%CI:1.28–2.42),and infectious complications(OR=2.01,95%CI:1.39–2.91)were predictors of cardioembolic stroke in the oldest age group.By contrast,heavy smoking,heart valve disease,hypertension,headache,early seizures,sensory deficit,and involvement of the posterior cerebral artery were independently associated with cardioembolic stroke in the younger group.Conclusions Identification of a differential clinical profile of cardioembolic stroke between patients aged 85 years or more and those younger than 85 years helps clinicians to the optimal management of ischemic infarction in the oldest segment of the population. | Ana Maria Carbajo-García Jonatan Cortés AdriàArboix Joan Massons Laura Díez Enric Vergés Jordi Arboix-Alió Luís García-Eroles | 2019 | Journal of Geriatric Cardiology2019，16，11： | 3 |
| 7 | Time course of sleep - relatedbreathing disorders in first - ever stroke or transient ischemic attack显示文摘 | Parra O Arboix A Bechich S | 2000 | Am J Re-spir Crit Care Med2000，161，： | 1 |
| 8 | Prognostic value of very early seizures for in-hospital mortality in atherothrombotic infarction 显示文摘 | Arboix A Comes E Garcia-Eroles L | 2003 | Eur Neurol2003，50，2： | 1 |
| 9 | Time Course of Sleep-related Breathing Disorders in First-ever Stroke or TIA显示文摘 | Parra O Arboix A Bechich S | 2000 | Am J Respir Crit Care Med2000，161，2： | 1 |
| 10 | Sleeprelated breathing disorders:impact on mortality of cerebrovascular disease显示文摘 | Parra O Arboix A Montserrat JM | | 0，，： | 1 |
| 11 | Clinical implications of headache in lacunar infarction : relevance of site of infart显示文摘 | Arboix A Grau-Olivares M Garcia-Eroles L | 2006 | Headache2006，46，7： | 1 |
| 12 | Impaired fastingglucose as a risk factor for atherothrombotic or lacunar cerebralinfarction, a case-control study显示文摘 | Baena-Dlez JM Arboix A Merino-Audi M | 2009 | Neurologia2009，24，1： | 1 |
| 13 | Lacunar stroke 显示文摘 | Arboix A Martf-Vilalta JL | 2009 | Expert Rev Neu-rother2009，9，2： | 1 |
| 14 | Lacunar stroke 显示文摘 | Arboix A Marti Vilalta J L | 2009 | Expert Rev Neurother2009，9，： | 1 |
| 15 | Cerebral infhrction in diabetes: clinical pattern, stroke subtypes, and predictors of in-hospital mortality显示文摘 | Arboix A Rivas A Garcia EL | 2005 | BMC Neurol2005，5，： | 1 |
| 16 | Cerebral infarction in diabetes:Clinical pattern, stroke subtypes, and predictors of inhospital mortality显示文摘 | Arboix A Rivas A Garcia-Eroles L | 2005 | BMC Neurol2005，5，1： | 1 |
| 17 | Sleep-related breath ing disorders: impact on mortality of cerebrovascular disease显示文摘 | Parra O Arboix A Montserrat J M | 2004 | EurRespirJ2004，24，26： | 1 |
| 18 | Acutecerebrovascular disease in women显示文摘 | Arboix A Oliveres M García-Eroles L | 2001 | Eur Neurol2001，45，： | 1 |
| 19 | Lacunar infarct and cognitive decline 显示文摘 | Arboix A | 2011 | Expert Rev Neurother2011，11，9： | 1 |
| 20 | Acute cardioembolic cerebral infarc- tion: answers to clinical questions 显示文摘 | Arboix Adria Allo Josefina | 2012 | Current Cardiology Re- views2012，8，1： | 1 |
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