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| 1 | X-ray-charged bright persistent luminescence in NaYF_(4):Ln^(3+)@NaYF_(4) nanoparticles for multidimensional optical information storage显示文摘NaYF_(4):Ln^(3+),due to its outstanding upconversion characteristics,has become one of the most important luminescent nanomaterials in biological imaging,optical information storage,and anticounterfeiting applications.However,the large specific surface area of NaYF_(4):Ln^(3+)nanoparticles generally leads to serious nonradiative transitions,which may greatly hinder the discovery of new optical functionality with promising applications.In this paper,we report that monodispersed nanoscale NaYF_(4):Ln^(3+),unexpectedly,can also be an excellent persistent luminescent(PersL)material.The NaYF_(4):Ln^(3+)nanoparticles with surface-passivated core–shell structures exhibit intense X-ray-charged PersL and narrow-band emissions tunable from 480 to 1060 nm.A mechanism for PersL in NaYF_(4):Ln^(3+)is proposed by means of thermoluminescence measurements and host-referred binding energy(HRBE)scheme,which suggests that some lanthanide ions(such as Tb)may also act as effective electron traps to achieve intense PersL.The uniform and spherical NaYF_(4):Ln^(3+)nanoparticles are dispersible in solvents,thus enabling many applications that are not accessible for traditional PersL phosphors.A new 3-dimensional(2 dimensions of planar space and 1 dimension of wavelength)optical information-storage application is demonstrated by inkjet-printing multicolor PersL nanoparticles.The multicolor persistent luminescence,as an emerging and promising emissive mode in NaYF_(4):Ln^(3+),will provide great opportunities for nanomaterials to be applied to a wider range of fields. | Yixi Zhuang Dunrong Chen Wenjing Chen Wenxing Zhang Xin Su Renren Deng Zhongfu An Hongmin Chen Rong-Jun Xie | 2021 | Light(Science & Applications)2021，10，7： | 12 |
| 2 | Developing potent PROTACs tools for selective degradation of HDAC6 protein显示文摘Dear Editor, Histone deacetylases (HDACs) are a family of enzymes that remove acetyl groups on histone and non-histone proteins, thereby playing a vital role in the modulation of gene expression and protein activity. Eighteen HDACs have been identified in human and subdivided into four classes including I, II (Ila, lib), III and IV (Seto et al., 2014). Among them, HDAC6 is a unique lib HD AC with dominant cytoplasmic localization and two functional catalytic domains. Besides the functions for deacetylation of histone, and modulation of a-tubulin, HSP90 and cortactin, HDAC6 also participates in protein trafficking and degradation, cell shape and migration (Valenzuela-Fernandez et al., 2008). The deregulation of HDAC6 is related to various diseases, such as neurodegenerative diseases, cancer and pathological autoimmune response (Batchu et al., 2016). Hence, it is especially important for directly controlling cellular HDAC6 protein levels to achieve therapeutic purposes. The traditional approaches of red u ci ng cellular protein levels mainly rely on genetic modifications, such as RNA interference, transcription activator-like effector nucleases, recombination-based gene knockout and clustered regularly interspaced short palindromic repeats (CRISPR-Cas9)(Boettcher et al., 2015). However, these approaches have failed to a certain degree to achieve acute and reversible changes of gene function. Furthermore, the complications of potential genetic compensation and/or spontaneous mutations arising in geneknockout models may lead to misinterpretations (Davisson etal., 2012;El-Brolosy etal., 2017). Therefore, it is urgent for developing a rapid, robust, and reversible approach to directly modulate HDAC6 protein levels. | Zixuan An Wenxing Lv Shang Su Wei Wu Yu Rao | 2019 | Protein & Cell2019，10，8： | 7 |
| 3 | A printed dual-wideband magneto-electric dipole antenna for WWAN/ LTE applications显示文摘 | FENG Botao LI Shufang AN Wenxing | 2014 | International Journal of Electronics and Communications2014，68，10： | 1 |
| 4 | Correction to: Developing potent PROTACs tools for selective degradation of HDAC6 protein显示文摘In the original publication the title of X axis in Fig.1G is in correctly published as'Compound(pmol/L)'.The correct title of X axis in Fig.1G should be read as'Compound(nmol/L)M.Figure 1.Development of selective HDAC6-degrading PROTACs.(A)The principle of PROTAC.(B)The structure of PROTAC,as shown in the upper portion.A binding mode of PROTAC(ball stick),HDAC6(PDB 5G0J,purple)and CRL4-CRBN(PDB 2HYE and 4CI3,colored cyan and gray)was simulated by Pymol. | Zixuan An Wenxing Lv Shang Su Wei Wu Yu Rao | 2019 | Protein & Cell2019，10，11： | 1 |
| 5 | Transferrin-guided intelligent nanovesicles augment the targetability and potency of clinical PLK1 inhibitor to acute myeloid leukemia显示文摘Acute myeloid leukemia(AML)remains a most lethal hematological malignancy,partly because of its slow development of targeted therapies compared with other cancers.PLK1 inhibitor,volasertib(Vol),is among the few molecular targeted drugs granted breakthrough therapy status for AML;however,its fast clearance and dose-limiting toxicity greatly restrain its clinical benefits.Here,we report that transferrin-guided polymersomes(TPs)markedly augment the targetability,potency and safety of Vol to AML.Vol-loaded TPs(TPVol)with 4%trans-ferrin exhibited best cellular uptake,effective down-regulation of p-PLK1,p-PTEN and p-AKT and superior apoptotic activity to free Vol in MV-4-11 leukemic cells.Intravenous injection of TPVol gave 6-fold higher AUC than free Vol and notable accumulation in AML-residing bone marrow.The efficacy studies in orthotopic MV-4-11 leukemic model demonstrated that TPVol significantly reduced leukemic cell proportions in periphery blood,bone marrow,liver and spleen,effectively enhanced mouse survival rate,and impeded bone loss.This transferrin-guided nano-delivery of molecular targeted drugs appears to be an interesting strategy towards the development of novel treatments for AML. | Yifeng Xia Jingnan An Jiaying Li Wenxing Gu Yifan Zhang Songsong Zhao Cenzhu Zhao Yang Xu Bin Li Zhiyuan Zhong Fenghua Meng | 2023 | Bioactive Materials2023，，3： | 0 |
| 6 | Integrated of Proximity-Coupling High-Order Modes Patch Antenna with Solar Cells for Sustainable Communication显示文摘An integration of single-layer proximitycoupling patch antenna and solar cells with bandwidth enhancement and optical energy harvesting is proposed for sustainable communication.For this purpose,many dual-function components are selected for designing the miniaturized solar cell antenna.On the one hand,by greatly affecting the current flow of the rectangular patch,vias and proximity-coupling are introduced to control the resonance modes frequency and matching,respectively,for wideband application,and the radiation performance property can be achieved by high-order mode.On the other hand,vias and proximity-coupling are beneficial to complete direct-current(DC)loop of solar cell and improve compatibility of DC-RF(radio frequency),whereas a high-order mode is beneficial to increase the area of collected light energy.To prove the working principle,fabricated and manufactured solar cell antenna.The measured and simulated results illustrate that the solar cell antenna gain is raised to as high as 9.27 d Bi in4.37 to 5.06 GHz applied to fifth generation communication(5G). | Jingyu Lai Yu Luo Ningning Yan Wenxing An Kaixue Ma | 2023 | China Communications2023，20，6： | 0 |
| 7 | Research on Effective Access for Strengthening and Improving the Management and Benefit use of Large Instruments显示文摘ng and Improving the Management and Benefit use of Large InstrumentsTX1PrefaceTheinstrumentisthebasicmeanstoengageteachingands... | Cui Zhongxing, Hu Mingxing, Chen Cunli, Kang Wenxing, Hua XianghanXi’an University of Technology Xi’an, 710048, P.R.China | 1998 | International Journal of Plant Engineering and Management1998，3，2： | 0 |
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