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| 1 | Comparison of imaging-based and pathological dimensions in pancreatic neuroendocrine tumors显示文摘AIM To establish the ability of magnetic resonance(MR) and computer tomography(CT) to predict pathologic dimensions of pancreatic neuroendocrine tumors(Pan NET) in a caseload of a tertiary referral center.METHODS Patients submitted to surgery for Pan NET at the Surgical Unit of the Pancreas Institute with at least 1 preoperative imaging examination(MR or CT scan) from January 2005 to December 2015 were included and data retrospectively collected. Exclusion criteria were: multifocal lesions, genetic syndromes, microadenomas or mixed tumors, metastatic disease and neoadjuvant therapy. Bland-Altman(BA) and Mountain-Plot(MP) statistics were used to compare size measured by each modality with the pathology size. Passing-Bablok(PB) regression analysis was used to check the agreement between MR and CT.RESULTS Our study population consisted of 292 patients. Seventy-nine(27.1%) were functioning Pan NET. The mean biases were 0.17 ± 7.99 mm, 1 ± 8.51 mm and 0.23 ± 9 mm, 1.2 ± 9.8 mm for MR and CT, considering the overall population and the subgroup of non-functioning-Pan NET, respectively. Limits of agreement(LOA) included the vast majority of observations, indicating a good agreement between imaging and pathology. The MP further confirmed this finding and showed that the two methods are unbiased with respect to each other. Considering ≤ 2 cm non-functioning-Pan NET, no statistical significance was found in the size estimation rate of MR and CT(P = 0.433). PBR analysis did not reveal significant differences between MR, CT and pathology.CONCLUSION MR and CT scan are accurate and interchangeable imaging techniques in predicting pathologic dimensions of Pan NET. | Salvatore Paiella Harmony Impellizzeri Elisabetta Zanolin Giovanni Marchegiani Marco Miotto Anna Malpaga Riccardo De Robertis Mirko D'Onofrio Borislav Rusev Paola Capelli Sara Cingarlini Giovanni Butturini Maria Vittoria Davì Antonio Amodio Claudio BassiAldo Scarpa Roberto Salvia Luca Landoni | 2017 | World Journal of Gastroenterology2017，23，17： | 4 |
| 2 | DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myelo- ma显示文摘 | Amodio N Leotta M Bellizzi D | 2012 | Oncotarget2012，，3： | 1 |
| 3 | Contribution of PKB/AKT signaling to thyroid cancer显示文摘 | VIGLIETTO G AMODIO N MALANGA D | 2011 | Front Biosci2011，16，： | 1 |
| 4 | Digital speckle correlation for strain measurement by image analysis显示文摘 | AMODIO D BROGGIATO G B | 2003 | Society for Experimental Mechanics2003，43，12： | 1 |
| 5 | DNA-demethylating and antitumor activity of synthetic miR-29b mimics in multiple myeloma显示文摘 | Amodio N Leotta M Bellizzi D | 2012 | Oncotarget2012，3，： | 1 |
| 6 | Central nervous sys- tem alterations in liver cirrhosis:the role of portal-systemic shunt and portal hypoperfusion显示文摘 | Del Piccolo F Sacerdoti D Amodio P | 2003 | Metab Brain Dis2003，18，1： | 1 |
| 7 | Central nervous system alterations in liver cirrhosis:the roal of portal-systemic shunt and portal hypoperfusion显示文摘 | Del Piccolo F Sacerdoti D Amodio P | 2003 | Metab Brain Dis2003，18，： | 1 |
| 8 | Neurological complications after orthotopic liver transplantation显示文摘 | P. Amodio A. Biancardi S. Montagnese P. Angeli P. Iannizzi U. Cillo D. D’Amico A. Gatta | 2007 | Digestive and Liver Disease2007，，8： | 1 |
| 9 | Individual differences in the regulation of intergroup bias:the role of conflict monitoring and neural signals for control显示文摘 | Amodio D M Devine P G Harmon-Jones E | | 0，，01： | 1 |
| 10 | Material characterization at high strain rate by Hopkinson bar tests and finite element optimization 显示文摘 | Sasso M Newaz G Amodio D | 2008 | Materials Science and Engineering A2008，487，12： | 1 |
| 11 | Material characterization at high strain rate by Hopkinson bar tests and finite element optimization显示文摘 | Sasso M Newaz G Amodio D | | 0，，1： | 1 |
| 12 | Meeting of minds: The medial frontal cortex and social cognition显示文摘 | Amodio D M Frith C D | 2006 | Na- ture Reviews Neuroscience2006，7，： | 1 |
| 13 | Individual differences in the regulation of intergroup bias: the role of conflict monitoring and neural signals for control 显示文摘 | Amodio D M Devine P G Harmon-Jones E | 2008 | Journal of Personality and Social Psychology2008，94，1： | 1 |
| 14 | HLA-G expres- sion levels influence the tolerogenic activity of human DC-10显示文摘 | Amodio G Comi M Tomasoni D | 2015 | Haematologica2015，100，4： | 1 |
| 15 | Hierarchy of high-frequen- cy orbital cycles in Cretaceous carbonate platform strata显示文摘 | D'Argenio B Ferreri V Amodio S | 1997 | Sedimen- tary Geology1997，113，： | 1 |
| 16 | The Social Neuroscience of Intergroup Relations 显示文摘 | AMODIO D M | 2008 | European Review of Social Psychology2008，，19： | 1 |
| 17 | Cyclostratigraphic and chronostratigraphic correlations in the Barremian-Aptian shallow-marine carbonates of the centrabsouthern Apen- nines (Italy)显示文摘 | Amodio S Ferreri V D'Argenio B | 2013 | Cretaceous Research2013，44，： | 1 |
| 18 | Renal function in H1V- infected children and adolescents treated with tenofovir disoproxil fumarate and protease inhibitors 显示文摘 | Pontrelli G Cotugno N Amodio D | 2012 | BMC Infect Dis2012，12，1： | 1 |
| 19 | HLA-G expres- sion on blasts and tolerogenic cells in patients affected by a- cute myeloid leukemia显示文摘 | Locafaro G Amodio G Tomasoni D | 2014 | J Immunol Res2014，63，： | 1 |
| 20 | HLA-G expression levels influence the tolerogenic activity of human DC-10显示文摘 | Amodio G Comi M Tomasoni D | 2015 | Haematologica2015，100，4： | 1 |
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