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| 1 | Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo. | Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman | 2017 | World Journal of Gastroenterology2017，23，21： | 9 |
| 2 | Neovascularization of the amniotic membrane as a biological immune barrier显示文摘 | Mahgoub M A Ammar A Fayez M | 2004 | Transplant Proc2004，36，4： | 1 |
| 3 | Immunomodulatory Effectsof Anesthetics during Thoracic Surgery显示文摘 | MAHMOUD K AMMAR A | 2011 | Anesthesiol ResPract2011，2011，31： | 1 |
| 4 | Pulmonary function in children after neonatal meconium aspiration syndrome 显示文摘 | Djemal N Ben Ammar H Masmoudi K Reguaieg R Trigui L Ben Humad A | 2008 | Arch Pediatr2008，15，2： | 1 |
| 5 | The relationship of the buccal branch of the facial nerve to the parotid duct 显示文摘 | Pogrel AM Schmidt B Ammar A | 1996 | Oral Maxillofac Surg1996，54，1： | 1 |
| 6 | Comparison of feature extractors for real-time object detection on android smartphone 显示文摘 | KHAIRULMUZZAMMIL S NURUL A AMMAR A | 2013 | Journal of Theoretical and Applied Information Technology2013，47，1： | 1 |
| 7 | Using of tara flour as partialsubstitute of wheat flour in bread making 显示文摘 | AMMAR M S HEGAZY A E BEDEIR S H | 2009 | World Journal of Dairy &Food Sciences2009，4，2： | 1 |
| 8 | Amblyopia screening for first and second-grade children in Jordan显示文摘AIM:To share the results of a national screening program for amblyopia in school children in the north of Jordan.METHODS:This is a prospective national screening study for amblyopia.The program rolls first and second-grade children(6 to 7 years old) in the north of Jordan.The eye examination included:best-corrected visual acuity,cover-uncover test,and cycloplegic retinoscopy.Monocular visual acuity was tested using an ETDRS visual acuity chart without correction.Moreover,children were tested with full cycloplegic refraction when the test criteria were met.Unilateral amblyopia was defined as a best-corrected visual acuity difference of 2 or more lines.In comparison,bilateral amblyopia was defined as a best-corrected visual acuity of 20/40 or worse in the best eye.RESULTS:The prevalence of amblyopia for the total sample tested(n=17 203) was 2.78%(n=479).The most common cause of amblyopia was hypermetropia(64.45%),followed by previous ocular surgeries(15.1%),myopia(10.43%),strabismus(9.39%),and congenital cataract(0.63%).CONCLUSION:This is the first and only study,identifing modifiable risk factors in Jordanian children with amblyopia.In their first couple of years of elementary education,many Jordanian children are affected by amblyopia and pass unnoticed.A more governmental effort is needed into screening programs to improve vision in the Jordanian population. | Khalil M.Al-Salem Mohammad S.Saleem Ismat Ereifej Hamzeh M.Alrawashdeh Rayed Falah Hussein Obeidat Asma Ali Abdlmohdi Raeda Zaki Al-Momani Layal Mohammed Hammad Omar Ahmad al-Habahbeh Yaqeen M.Assassfeh Laith Ramzi Najib Al-Qsous Ashraf Hatim Adeeb Nasraween Tariq A.Al Maaitah Deya'-Aldin Muneer Hasan Aqeel Ibtehal Eyadeh Awad Alabdulrazzg Abdullah Mahmoud Mohammad Murad Amany Jehad Faleh AL-Zurqan Enas Jamal Mohammad Jaradat Slsabela Emad Suliman Aldhoon Ala'a Majed Dmour Ahmad Talal Asassfeh Jeries Ayman Halaseh Abdel Aziz Ammar Daoud Waha Ayman Alkasasbeh Kholoud GH.Matar | 2022 | International Journal of Ophthalmology(English edition)2022，15，2： | 1 |
| 9 | The effects of intrathecal morphine on patients undergoing minimally invasive direct coronary artery bypass surgery显示文摘 | Zisman E Shenderey A Ammar R | 2005 | J Cardiothorac Vasc Anesth2005，19，1： | 1 |
| 10 | New excised-leaf assay method to test inoeulativity of Asian citrus psyllid (Hemiptera: Psyllidae) with Candidatus Liberibacter asiatic'us associated with citrus huanglongbing disease显示文摘 | Ammar E D Waller A J Hall D G | 2013 | Journal of economic en- tomology2013，106，1： | 1 |
| 11 | Enhanced and parameterless Locality Preserving Projections for face recognition 显示文摘 | Fadi D Ammar A | 2013 | Neurocomputing (S0925-2312)2013，99，1： | 1 |
| 12 | Effect of on-field inoculation of phaseolus vulgaris with rhizobia on soil bacterial communities显示文摘 | Trabelsi D Mengoni A Ammar H B | 2011 | FEMS Microbiology Ecology2011，77，1： | 1 |
| 13 | Expression of Fas antigen and Fas ligand in bronchoalveolar lavage from silicosis patients显示文摘 | Hamzaoui A Ammar J Grairi H | 2003 | Mediators Inflamm2003，12，4： | 1 |
| 14 | Root cell characteristics of two wheat species differing in their sensitivity to NaCl in response to salt stress显示文摘 | Jbir N Ammar S Ayadi A 2003 | 2003 | Journal of Trace and Microprobe Techniques2003，21，4： | 1 |
| 15 | Influences of alloying elements, solution treatment time and quenching media on quality indices of 413-type AI-Si casting alloys 显示文摘 | AMMAR H R MOREAU C SAMUEL A M SAMUEL F H DOTY H W | 2008 | Materials Science and Engineering A2008，489，1： | 1 |
| 16 | Insect Vector Interactions with Persistently Transmitted Viruses显示文摘 | Hoqenhout S A Ammar E D Whitfield A E | 2008 | Annual Review of Phytopathology2008，，46： | 1 |
| 17 | NonDestructive Ultrasonic Eevaluation of CFRP-Concrete Specimens Subjected to Accelerated Aging Conditions显示文摘 | Mahmoud A R Ammar H H Mukdadi O M | 2010 | NDT&E International2010，43，7： | 1 |
| 18 | Comparison of three SN methods to correct for microbial contamination when assessing in situ protein degradability of fresh forages显示文摘 | Kamoun M Ammar H Th6wis A Beckers Y France J L6pez S | 2014 | Journal of Animal Science2014，92，11： | 1 |
| 19 | Effect of on-field inoculation of Phaseolus vulgaris with rhizobia on soil bacterial communities显示文摘 | Trabelsi D Mengoni A Ben Ammar H | 2011 | FEMS Microbiology Ecology2011，77，1： | 1 |
| 20 | Amelioration of doxorubicin-induced cardiotoxicity by deferiprone in rats显示文摘 | Ammar el-SM Said S A Suddek G M | 2011 | Can J Physiol Pharmacol2011，89，4： | 1 |
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