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| 1 | Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease显示文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD. | Thiago H Freitas Elias Andreoulakis Gilberto S Alves Hesley LL Miranda Lúcia LBC Braga Thomas Hyphantis André F Carvalho | 2015 | World Journal of Gastroenterology2015，21，21： | 10 |
| 2 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 3 | Increased exhaled nitrite in children with allergic asthma is not related to nitric oxide formation 显示文摘 | Marteus H Hedlin G Alving G | 2008 | Clin Respir J2008，2，4： | 1 |
| 4 | Biomaterial-induced sar-coma:a novel model to study preneoplastic change显示文摘 | Kirkpatrick C J Alves A Khler H | 2000 | Am JPathol2000，156，4： | 1 |
| 5 | Erythromycin and feeding introlerance in preterm infants:a randomised trail显示文摘 | Alv H Abdel-Hady H Khashaba M | 2007 | J Perinatol2007，27，1： | 1 |
| 6 | Theoretical optical parameters for Ⅲ-nitride semiconductors显示文摘 | Silva Pinto E de Paiva R de Carvalho L C Alves H W L Alves J L A | 2003 | Microelectronics Journal2003，34，： | 1 |
| 7 | Differntial reactivity for galectin-3 in Hurthle adenomas and carcinomas显示文摘 | Nascimento MC Bisi H Alves VA | 2001 | Endocr Pathol2001，12，3： | 1 |
| 8 | Nontrival solutions for a class of semilinear biharmonie problems involving critical exponents 显示文摘 | Alves C O Joao Marcos do O Miyagaki O H | 2001 | Nonlinear Analysis2001，46，： | 1 |
| 9 | Nitriding of titanium disks and industrial dental implants using hollow cathode discharge显示文摘 | Jr ALVES C GUERRA NETO C L B MORAIS G H S | 2006 | Surface and Coatings Technology2006，200，： | 1 |
| 10 | Polymorphisms in the ABCB1gene in phenobarbital responsive and resistant idiopathic epileptic Border Collies显示文摘 | Alves L Hülsmeyer V Jaggy A et a1 | 2011 | J Vet Intern Med2011，25，： | 1 |
| 11 | Mental health and physical inactivity during pregnancy:a cross-sectional study nested in the BRISA cohort study 显示文摘 | Takahasi E H Alves M T Alves G S | 2013 | Cad Sande Publica2013，29，8： | 1 |
| 12 | Dislocation reduction in GaN grown by hydride vapor phase epitaxy via growth interruption modulation显示文摘 | W Zhang Roesel S Alves H R | 2001 | Appl Phys Lett2001，78，： | 1 |
| 13 | Friedel-Crafts acylaiton of anisole with acetic anhydride over silica-supported hetempolyphostungstic acid (HPW/SiO2 )显示文摘 | CARDOSO L A M ALVES W It GONZAGA A R E AGUIAR L M G ANDRADE H M C | 2004 | J Mol Catal A2004，209，12： | 1 |
| 14 | Emission quantum yield of europium (Ⅲ) mixed complexes with thenoyhriiluoroacetonate and some aromatic ligands 显示文摘 | Silva F R G E Menezes J F S Rocha G B Rocha G B Alves S Brito H F Longo R L Malta O L | 2000 | Journal of Alloys and Compounds2000，303，304： | 1 |
| 15 | Optical Investigations on Excitons Bound to Impurities and Dislocations in ZnO显示文摘 | Alves H Pfisterer D Zeuner A | 2003 | Optical Materials2003，23，： | 1 |
| 16 | Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer显示文摘 | ALVES P M LIVY N BOUZOURENE H | 2007 | Cancer/mmunol Immu-nother2007，56，6： | 1 |
| 17 | Apolipoprotein E polymorphism and its association with serum lipid levels in Brazilian children 显示文摘 | De Frana E Alves J B Hutz M H | 2004 | Hum Biol2004，76，2： | 1 |
| 18 | Biomaterial-induced sarcoma: A novel model to study preneoplastic change显示文摘 | Kirkpatrick CJ Alves A Kohler H | 2000 | AmJ Pathol2000，156，4： | 1 |
| 19 | 显示文摘 | Zhou H Alves H Hofmann D M | 2002 | Appl Phys Lett2002，80，2： | 1 |
| 20 | Response of minimally processed carambola to chemical treatments and low-oxygen atmospheres显示文摘 | TEIXEIRA G H A DURIGAN J F ALVES R E | 2008 | Postharvest Biology and Technology2008，48，3： | 1 |
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