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| 1 | Influence of vitamin D on liver fibrosis in chronic hepatitis C: A systematic review and meta-analysis of the pooled clinical trials data显示文摘AIM To investigate the relationship between vitamin D and liver fibrosis in hepatitis C-monoinfected or hepatitis C virus(HCV)-human immunodeficiency virus(HIV) coinfected patients. METHODS Pertinent studies were located by a library literature search in PubM ed/Embase/Cochrane/Scopus/LILACS by two individual reviewers. Inclusion criteria:(1) studies with patients with HCV or co-infected HCV/HIV;(2) studies with patients ≥ 18 years old;(3) studies that evaluated liver fibrosis stage, only based on liver biopsy; and(4) studies that reported serum or plasma 25(OH)D levels. Studies that included pediatric patients, other etiologies of liver disease, or did not use liver biopsy for fibrosis evaluation, or studies with inadequate data were excluded. Estimated measures of association reported in the literature, as well as corresponding measures of uncertainty, were recorded and corresponding odds ratios with 95%CI were included in a meta-analysis. RESULTS The pooled data of this systematic review showed that 9 of the 12 studies correlated advanced liver disease defined as a Metavir value of F3/4 with 25(OH) D level insufficiency. The meta-analysis indicated a significant association across studies.CONCLUSION Low vitamin D status is common in chronic Hepatitis C patients and is associated with advanced liver fibrosis. | Alia S Dadabhai Behnam Saberi Katie Lobner Russell T Shinohara Gerard E Mullin | 2017 | World Journal of Hepatology2017，9，5： | 6 |
| 2 | Vitamin D levels do not predict the stage of hepatic fibrosis in patients with non-alcoholic fatty liver disease: A PRISMA compliant systematic review and meta-analysis of pooled data显示文摘AIM To investigate the relationship between 25-hydroxyvitamin D [25(OH)D] levels and fibrosis stage in patients with non-alcoholic fatty liver disease(NAFLD).METHODS Two individual reviewers identified relevant studies using the Pub Med, EMBASE, Cochrane, and Scopus databases. Inclusion criteria were as follows:(1) Studies that evaluated adults with NAFLD and serum or plasma 25(OH)D levels; and(2) assessed fibrosis stage using liver biopsy. A rigorous analysis yielded six articles as having sufficient data to employ in evaluating the association of serum vitamin D levels in patients with NAFLD based on their liver fibrosis stage by histopathological analysis. The lead investigators of each of the six studies were contacted and the data were collected. To meta-analyze vitamin D levels in F0-F2 vs F3-F4 fibrosis, a random-effects meta-analysis fit using restricted maximum likelihood was applied. To examine trends across each stage of fibrosis with respect to vitamin D levels, a meta-regression was performed. P < 0.05 was considered statistically significant. RESULTS A total of 937 subjects from six studies were included in the final analysis to evaluate the association of serum vitamin D levels in patients with NAFLD based on their liver fibrosis stage by histopathological analysis. The lead investigators of each of the six studies were contacted and the data were collected. First, the investigators performed a meta-analysis to compare serum vitamin D levels in patients with NAFLD with stage F0-F2 compared to F3-F4, which did not show significance [meta-estimate of the pooled mean difference =-0.86, P = 0.08(-4.17, 2.46)]. A metaregression evaluation of serum vitamin 25(OH)D levels across the individual stages(F0-F4) of fibrosis did not show an association for the six included studies.CONCLUSION Low vitamin D status is not associated with higher stages of liver fibrosis in patients with NAFLD. | Behnam Saberi Alia S Dadabhai Julie Nanavati Lin Wang Russell T Shinohara Gerard E Mullin | 2018 | World Journal of Hepatology2018，10，1： | 3 |
| 3 | Effect of zine on free radicals and proline in Brassica and Cajanus显示文摘 | Alia K V Prasad S K Saradhi P P | 1995 | Phytochemistry1995，39，： | 1 |
| 4 | Effect of zinc on free radicals and proline in Brassica and Cajanus显示文摘 | Alia Prasad K V S K Saradhi P P | 1995 | Phytochemistry1995，39，1： | 1 |
| 5 | Detection of 3-carene in mango using aquartz crystal microbalance sensor显示文摘 | ALIA S B GHATAKB B GUPTAB S D | 2016 | Sensors and Actuators:B2016，230，： | 1 |
| 6 | Influence of quereetin and rutin on growth and antioxidant defense system of a human hepatoma cell line(HepG2)显示文摘 | Alia M Mateos R Ramos S et a1 | 2006 | Eur J Nutr2006，45，1： | 1 |
| 7 | Heat transfer of aqueous suspension of carbon nanotubes (CNT nanofluids) 显示文摘 | Ding Y L Alias H Wen D S | 2006 | International Journal of Heat and Mass Transfer2006，49，： | 1 |
| 8 | Swelling and mechanical properties of superabsorbent hydrogels based on Tara gum/acrylic acid synthesized by gamma radiation 显示文摘 | Abd Alia S G Sen M El-Naggar A W M | 2012 | Carbohydrate Polymers2012，89，2： | 1 |
| 9 | Interfacial stress transfer of near surface-mounted FRP- to-concrete joints显示文摘 | Mohamed Alia M S Oehlersa D J Griffitha M C | 2008 | Engineering Structures2008，30，： | 1 |
| 10 | Magicangle spinning (MAS) NMR:a new tool to study the spa-tial and electronic structure of photosynthetic complexes显示文摘 | ALIA A GANAPATHY S DE GROOT H J M | 2009 | Photosynthesis Research2009，102，23： | 1 |
| 11 | Hydrocortisone nanosuspen- sions for ophthahnic delivery: A comparative study between mi- crofiuidic nanoprecipitation and media milling 显示文摘 | ALI H S YORK P ALIA M | 2011 | J Controlled Release2011，149，2： | 1 |
| 12 | Effect of pH on ZnO nanoparticle properties synthesized by sol- gel centrifugation显示文摘 | Alias S S Ismail A B Mohamad A A | 2010 | J Alloys Compd2010，499，2： | 1 |
| 13 | Colour removal from landfill leachate by coagulation and flocculation processes显示文摘 | AZIZ H A ALIAS S ADLAN M N | 2007 | Bioresour Technol2007，98，： | 1 |
| 14 | Quercetin prelects human hep- atoma HepG2 against oxidative stress induced by tea-butyl hydroperoxide 显示文摘 | Alia M Ramos S Mateos R el al | 2006 | Toxicol Appl Pbarmacol2006，212，2： | 1 |
| 15 | A new acylated steroid glucoside from Perovskia atriplicifolia 显示文摘 | Alia M S Saleem M Erian A W | 2001 | Fitoterapia2001，72，6： | 1 |
| 16 | Effects of some ante - mortem stressors on peri - mortem and post - mortem biochemical changes and tenderness in broiler breast muscle 显示文摘 | ALIA S A HARRISON A P JENSEN J F | 1999 | Worlds Poult Sci J1999，55，4： | 1 |
| 17 | IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer显示文摘 | ALIA Z SANDHU M S LUBEN R N | 2006 | Human Molecular Genetics2006，15，1： | 1 |
| 18 | Effect of zinc on free radicals and proline in V, rassiea and Cajanus 显示文摘 | Alia Prasad K V S K Saradhi P P | 1995 | Phytochemistry1995，39，： | 1 |
| 19 | Spectrophotometric determination of ciprofloxaein, enrofloxacin and pefloxacin through charge transfer complex formation 显示文摘 | Mostafa S E1-Sadek M Esmail Awad Alia | 2002 | Journal of Pharmaceutical and Biomedical Analysis2002，27，12： | 1 |
| 20 | Response of the antioxidant defense system to t-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2) 显示文摘 | Alia M Ramos S Mateos R | 2005 | J Biochem Mol Toxicol2005，19，2： | 1 |
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