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| 1 | 原发性低密度脂蛋白胆固醇≥4.94mmol/L的男性降低低密度脂蛋白胆固醇对心血管病的影响显示文摘原发性低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)≥4.94mmol/L(190mg/dL)的患者由于长期暴露在显著升高的LDL-C下,心血管动脉粥样硬化的风险更高。因此,对于这些患者通常建议采用他汀类药物治疗,但是缺少随机试验证据支持。在该研究中,研究者提供了一些降低LDL-C对心血管病影响的初级预防资料。 | Vallejo-Vaz AJ Robertson M Catapano AL Watts GF Kastelein JJ Packard CJ Ford I Ray KK 黄洁 叶鹏 | 2017 | 中华高血压杂志2017，25，10： | 5 |
| 2 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 3 | 非洲血统男性的肌肉衰减与新发高血压的关系显示文摘骨骼肌中异位脂肪组织浸润增加与胰岛素抵抗和糖尿病相关。该研究评估骨骼肌脂肪组织的变化能否预测非洲血统男性随后的高血压发展。在Tobago健康研究中,使用计算机断层扫描测定非洲血统男性(年龄40-91岁)的小腿肌肉间脂肪组织和骨骼肌衰减情况,进行前瞻性纵向研究。高血压定义为收缩压≥140和(或)舒张压≥90mmHg(1mmHg=0.133kPa),或接受降压药物治疗。 | 刘莉 叶鹏 Zhao Q Zmuda JM Kuipers AL Bunker CH Patrick AL Youk AO Miljkovic I | 2017 | 中华高血压杂志2017，25，3： | 2 |
| 4 | Efficacy and safety of treatment of hepatitis C virus infection in renal transplant recipients显示文摘AIM: To assess the efficacy and safety of combinedpegylated interferon and ribavirin therapy in hepatitis C virus (HCV) infection in renal transplant recipients. METHODS: This is a retrospective chart review of post renal transplant patients who were positive for anti-HCV and HCV-RNA, and who have received treatment with combination of pegylated interferon and ribavirin between October 2003 and December 2008. Only patients with stable graft function and absence of evidence of cirrhosis and who received the therapy for continuous 48 wk were included. Nineteen patients (13 male and 6 female) were identified and included. The patient's complete blood count, liver and kidney prof ile, and cal- culated glomerular f iltration rate (GFR) were monitored every 6-8 wk while on treatment. HCV-RNA was tested at 12 wk for early virological response, at 48 wk for end of treatment response (ETR), and then retested at 24, and 48 wk after completion of therapy for sustained virological response (SVR). Liver biopsies were obtained before treatment from all patients and graft kidney biopsies were performed as required. RESULTS: Of the entire cohort, 9 patients (47.4%) showed an ETR and 8 had SVR (42.1%). Of the 8 patients with abnormal alanine aminotransferase (ALT) levels at baseline, 78.9% had their ALT normalized (including the virological non responders). ALT was normal in all responders at the end of therapy and at 24 wk post therapy (100%). Only one patient (5.3%) developed an increase in creatinine and decline in GFR from baseline towards the end of treatment. This patient's kidney biopsy revealed borderline rejection. There was no impact on response by HCV-genotype, initial HCV RNA load, age or sex of the patient or duration post transplant before commencement of therapy. All patients tolerated treatment in the same way as non-transplant with no unusual or increased occurrence of side effects. CONCLUSION: The combination of pegylated interferon and ribavirin is effective in suppressing HCV-RNA,with a low risk of graft rejection or failure in HCV infected renal transplant recipients. | Abdulrahman A Aljumah Mohamed A Saeed Ahmed I Al Flaiw Ibrahim H Al Traif Abduljaleel M Al Alwan Salem H Al Qurashi Ghormallah A Al Ghamdi Fayez F Al Hejaili Mohammed A Al Balwi Abdulla A Al Sayyari | 2012 | World Journal of Gastroenterology2012，18，1： | 2 |
| 5 | Effect of surface treatment on bond strength of low-fusing porcelain to commercially pure titanium显示文摘 | Al Hussaini I Al Wazzan KA | 2005 | J Prosthet Dent2005，94，4： | 1 |
| 6 | Influence of circadian rhythm on fetal and maternal Doppler parameters--is a diurnal variation detectable?显示文摘 | STABOULIDOU I WüSTEMANN M SCHMIDT P et al | 2008 | Z Geburtshilfe Neonatol2008，212，2： | 1 |
| 7 | Microbial growth in soil and nitrogen turnover: model calibration with laboratory data 显示文摘 | BLAGODATSKY S A YEVDOKIMOV I V LARIONOVA A A et al | 1998 | Soil Biology and Biochemistry1998，30，： | 1 |
| 8 | Effect of surface treatment on bond strength of low fusing porcelain to commericially pure titanium 显示文摘 | Al Hussaini I Al Wazzan KA | 2005 | J Prosthet Dent2005，94，： | 1 |
| 9 | Per('utaneous injec- tion of methyl methacrylale in the vertebral body fi)r the trestment of various diseases:percutaneous vertebroplasty(abstracl)显示文摘 | Bascoulerguc Y I)uqttesnel J Leclercq R e! al | 1988 | Radi- ohJgy1988，169，： | 1 |
| 10 | The effect of cerebral monitoring on recovery after general anesthesia: a comparison of the auditory evoked potential and bispectral index devices with standard clinical practice 显示文摘 | RECART A GASANOVA I WHITE P F ct al | 2003 | AnesthAnalg2003，97，6： | 1 |
| 11 | Association between blood pressure variability and inflammatory marker in hypertensive patients 显示文摘 | Kim K I Lee J H Chang H J et al | 2008 | Circ J2008，72，2： | 1 |
| 12 | The sirtuinl activator SRT3025 down - regulates sclerostin and rescues ovariectumy - induced bone loss and biomechanical deterioration in female mice 显示文摘 | Al'tsi H Cohen -Kfir E Gurt I | 2014 | Endocrinology2014，155，9： | 1 |
| 13 | Liver iron concentration quantification by MRI:are recommended protocols accurate enough for clinical practice显示文摘 | Castiella A Alústiza J M Emparanza J I | | 0，，1： | 1 |
| 14 | The mechanisms of action of phototherapy in the treatment of the most common dermatoses显示文摘 | Bulat V ~itum M Dcdiol I el al | 2011 | Collegium Antropologicum2011，35，2： | 1 |
| 15 | Operational principles of a controlled shunting reactor of the transformer type显示文摘 | ALEKSANDROV G N AL BERTINSKIJ B I SHKUROPAT I A | 1995 | Russian Electrical Engineering1995，66，11： | 1 |
| 16 | 赣西地区肉牛胃肠道寄生虫病调查及防治显示文摘为了调查清楚赣西地区肉牛胃肠道寄生虫的感染情况,结合饱和蔗糖溶液漂浮、甲醛-乙酸乙酯-改良耐酸染色、卢戈氏碘液染色、离心沉淀以及显微镜观察等多种方法对赣西地区肉牛的粪便进行处理与观察。从168份样本的结果来看,总体感染率为18.45%,大多数是单一感染,其中,艾美耳球虫感染率最高(8.93%),其次是类圆线虫(5.36%),其他虫种包括莫尼茨绦虫、肝片吸虫和隐孢子虫。调查结果表明,赣西地区肉牛胃肠道寄生虫对阿苯达唑伊维菌素预混剂敏感,该药对寄生虫具有良好的杀虫效果,但该药对球虫的驱杀效果不佳,球虫可以通过抗寄生虫药物如盐酸氨丙啉、莫能霉素、磺胺二甲嘧啶来控制。 | 康劲文 郑文亚 彭瑞妮 Hamad al i hamad Kassim al i bakar Habiba mkomre pandu 刘犇 | 2019 | 中国兽医杂志2019，55，12： | 1 |
| 17 | Fabrication and optical properties of ultrathin CdSe filaments incorporated into the nanochannels of fibrous magnesium silicates 显示文摘 | Poborchii V V Al'perovich V I Nozue Y | 1997 | Journal of Physics : Condensed Matter1997，9，26： | 1 |
| 18 | Enzyme conversion immunoassay for determining total homocysteine in plasma or serum 显示文摘 | Frantzen F Faaren AL Alfheim I | 1998 | ClinChem1998，44，2： | 1 |
| 19 | a quantitative analysis显示文摘 | LASLETT G M GREEN P F DUDDY I R et' al Thermal annealing of fission tracks in apatite 2 | 1987 | Chemical Geology1987，65，1： | 1 |
| 20 | Global optimization of stochastic black box systems via sequential Kriging meta-models 显示文摘 | Huang D Allen T T Notz W I et aL | 2006 | Journal of Global Optimization2006，34，3： | 1 |
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