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| 1 | Effectiveness of probiotics in irritable bowel syndrome:Updated systematic review with meta-analysis显示文摘AIM:To investigate the efficacy of probiotics in irritable bowel syndrome(IBS) patients.METHODS:Pub Med,Cochrane library,Scopus,Google Scholar,and Clinicaltrial.gov databases were searched for literature published between September 2007 and December 2013.The applied Mesh terms were 'probiotics,' 'irritable bowel syndrome,' and 'irritable bowel syndrome treatment.' The collected data contained24 clinical trials,of which 15 were eligible for meta-analysis and nine were reviewed systematically.All studies were randomized placebo-controlled trials in patients with IBS that investigated the efficacy of probiotics in IBS improvement.The Jadad score was used to assess the methodological quality of trials.The quality scale ranges from 0 to 5 points,with a score ≤ 2 indicating a low quality report,and a score of ≥3 indicating a high quality report.Relative risk(RR),standardized effect size,and 95%CI were calculated using the Der Simonian-Laird method.The Cochran Q test was used to test heterogeneity with P < 0.05.Funnel plots were constructed and Egger's and BeggMazumdar tests were performed to assess publication bias.RESULTS:A total of 1793 patients were included in the meta-analysis.The RR of responders to therapies based on abdominal pain score in IBS patients for two included trials comparing probiotics to placebo was 1.96(95%CI:1.14-3.36;P = 0.01).RR of responders to therapies based on a global symptom score in IBS patients for two included trials comparing probiotics with placebo was 2.43(95%CI:1.13-5.21;P = 0.02).For adequate improvement of general symptoms in IBS patients,the RR of seven included trials(six studies) comparing probiotics with placebo was 2.14(95%CI:1.08-4.26;P = 0.03).Distension,bloating,and flatulence were evaluated using an IBS severity scoring system in three trials(two studies) to compare the effect of probiotic therapy in IBS patients with placebo,the standardized effect size of mean differences for probiotics therapy was-2.57(95%CI:-13.05--7.92).CONCLUSION:Probiotics reduce pain and symptom severity scores.The results demonstrate the beneficial effects of probiotics in IBS patients in comparison with placebo. | Tina Didari Shilan Mozaffari Shekoufeh Nikfar Mohammad Abdollahi | 2015 | World Journal of Gastroenterology2015，21，10： | 51 |
| 2 | Role of dietary polyphenols in the management of peptic ulcer显示文摘Peptic ulcer disease is a multifactorial and complex disease involving gastric and duodenal ulcers.Despite medical advances,the management of peptic ulcer and its complications remains a challenge,with high morbidity and death rates for the disease.An accumulating body of evidence suggests that,among a broad reach of natural molecules,dietary polyphenols with multiple biological mechanisms of action play a pivotal part in the management of gastric and duodenal ulcers.The current review confirmed that dietary polyphenols possess protective and therapeutic potential in peptic ulcer mediated by:improving cytoprotection,re-epithelialization,neovascularization,and angiogenesis; up-regulating tissue growth factors and prostaglandins; down-regulating anti-angiogenic factors; enhancing endothelial nitric oxide synthasederived NO; suppressing oxidative mucosal damage; amplifying antioxidant performance,antacid,and antisecretory activity; increasing endogenous mucosal defensive agents; and blocking Helicobacter pylori colonization associated gastric morphological changes and gastroduodenal inflammation and ulceration.In addition,anti-inflammatory activity due to downregulation of proinflammatory cytokines and cellular and int e r c e llular adhe s ion age nt s,s uppr e s s ing leukocyte-endothelium interaction,inhibiting nuclear signaling pathways of inflammatory process,and modulating intracellular transduction and transcription pathways have key roles in the anti-ulcer action of dietary polyphenols.In conclusion,administration of a significant amount of dietary polyphenols in the human diet or as part of dietary supplementation along with conventional treatment can result in perfect security and treatment of peptic ulcer.Further welldesigned preclinical and clinical tests are recommended in order to recognize higher levels of evidence for the confirmation of bioefficacy and safety of dietary polyphenols in the management of peptic ulcer. | Mohammad Hosein Farzaei Mohammad Abdollahi Roja Rahimi | 2015 | World Journal of Gastroenterology2015，21，21： | 34 |
| 3 | Nano-microbubble flotation of fine and ultrafine chalcopyrite particles显示文摘As is well known to mineral processing scientists and engineers, fine and ultrafine particles are difficult to float mainly due to the low bubble-particle collision efficiencies. Though many efforts have been made to improve flotation performance of fine and ultrafine particles, there is still much more to be done. In this paper, the effects of nano-microbubbles(nanobubbles and microbubbles) on the flotation of fine( 38 + 14.36 lm) and ultrafine( 14.36 + 5 lm) chalcopyrite particles were investigated in a laboratory scale Denver flotation cell. Nano-microbubbles were generated using a specially-designed nanomicrobubble generator based on the cavitation phenomenon in Venturi tubes. In order to better understand the mechanisms of nano-microbubble enhanced froth flotation of fine and ultrafine chalcopyrite particles, the nano-microbubble size distribution, stability and the effect of frother concentration on nanobubble size were also studied by a laser diffraction method. Comparative flotation tests were performed in the presence and absence of nano-microbubbles to evaluate their impact on the fine and ultrafine chalcopyrite particle flotation recovery. According to the results, the mean size of nano-microbubbles increased over time, and decreased with increase of frother concentration. The laboratory-scale flotation test results indicated that flotation recovery of chalcopyrite fine and ultrafine particles increased by approximately 16–21% in the presence of nano-microbubbles, depending on operating conditions of the process. The presence of nano-microbubbles increased the recovery of ultrafine particles( 14.36 + 5 lm) more than that of fine particles( 38 + 14.36 lm). Another major advantage is that the use of nano-microbubbles reduced the collector and frother consumptions by up to 75% and 50%,respectively. | Ahmadi Rahman Khodadadi Darban Ahmad Abdollahy Mahmoud Fan Maoming | 2014 | International Journal of Mining Science and Technology2014，24，4： | 28 |
| 4 | Effi cacy of tricyclic antidepressants in irritable bowel syndrome:A meta-analysis显示文摘We aimed to evaluate the efficacy of tricyclic antidepressants(TCAs) as a therapeutic option for irritable bowel syndrome(IBS) through meta-analysis of randomized controlled trials.For the years 1966 until September 2008,PubMed,Scopus,Web of Science,and Cochrane Central Register of Controlled Trials were searched for double-blind,placebo-controlled trials investigating the effi cacy of TCAs in the management of IBS.Seven randomized,placebo-controlled clinical trials met our criteria and were included in the metaanalysis.TCAs used in the treatment arm of these trials included amitriptyline,imipramine,desipramine,doxepin and trimipramine.The pooled relative risk for clinical improvement with TCA therapy was 1.93(95% CI:1.44 to 2.6,P<0.0001).Effect size of TCAs versus placebo for mean change in abdominal pain score among the two studies was -44.15(95% CI:-53.27 to -35.04,P<0.0001).It is concluded that low dose TCAs exhibit clinically and statistically signifi cant control of IBS symptoms. | Roja Rahimi Shekoufeh Nikfar Ali Rezaie Mohammad Abdollahi | 2009 | World Journal of Gastroenterology2009，15，13： | 22 |
| 5 | A systematic review of effi cacy and tolerability of mebeverine in irritable bowel syndrome显示文摘We evaluated the eff icacy and tolerability of mebeverine, a musculotropic antispasmodic agent, in irritable bowel syndrome (IBS) and compared its usual dosages by meta-analysis. Medical databases and all relevant literature were searched from 1965 to June 2009 for any placebo-controlled clinical trials of mebeverine, using search terms such as mebeverine, clinical trials, and IBS. Eight randomized trials met our criteria, including six trials that compared mebeverine with placebo and two that compared mebeverine tablets with capsules. These eight trials included 555 patients randomized to receive either mebeverine or placebo with 352 (63%)women and 203 (37%) men in all subtypes of IBS. The pooled relative risk (RR) for clinical improvement of mebeverine was 1.13 (95% CI: 0.59-2.16, P = 0.7056) and 1.33 (95% CI: 0.92-1.93, P = 0.129) for relief of abdominal pain. The efficacy of mebeverine 200 mg compared to mebeverine 135 mg indicated RRs of 1.12 (95% CI: 0.96-1.3, P = 0.168) for clinical or global improvement and 1.08 (95% CI: 0.87-1.34, P = 0.463) for relief of abdominal pain. Thus, mebeverine is mostly well tolerated with no signif icant adverse effects; however, its eff icacy in global improvement of IBS is not statistically signif icant. | Mahnaz Darvish-Damavandi Shekoufeh Nikfar Mohammad Abdollahi | 2010 | World Journal of Gastroenterology2010，16，5： | 17 |
| 6 | A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity显示文摘This review focuses on the efficacy and safety of effective herbal medicines in the management of obesity in humans and animals. PubMed, Scopus, Google Scholar, Web of Science, and IranMedex databases were searched up to December 30, 2008. The search terms were 'obesity' and ('herbal medicine' or 'plant', 'plant medicinal' or 'medicine traditional') without narrowing or limiting search elements. All of the human and animal studies on the effects of herbs with the key outcome of change in anthropometric measures such as body weight and waist-hip circumference, body fat, amount of food intake, and appetite were included. In vitro studies, reviews, and letters to editors were excluded. Of the publications identified in the initial database, 915 results were identified and reviewed, and a total of 77 studies were included (19 human and 58 animal studies). Studies with Cissus quadrangularis (CQ), Sambucus nigra , Asparagus officinalis , Garcinia atroviridis , ephedra and caffeine, Slimax (extract of several plants including Zingiber officinale and Bofutsushosan) showed a significant decrease in body weight. In 41 animal studies, significant weight loss or inhibition of weight gain was found. No significant adverse effects or mortality were observed except in studies with supplements containing ephedra,caffeine and Bofutsushosan. In conclusion, compounds containing ephedra, CQ, ginseng, bitter melon, and zingiber were found to be effective in the management of obesity. Attention to these natural compounds would open a new approach for novel therapeutic and more effective agents. | Shirin Hasani-Ranjbar Neda Nayebi Bagher Larijani Mohammad Abdollahi | 2009 | World Journal of Gastroenterology2009，15，25： | 14 |
| 7 | Herbal medicines for the management of irritable bowelsyndrome:A comprehensive review显示文摘Irritable bowel syndrome (IBS) is a functional gut disorder with high prevalence.Because of various factors involved in its pathophysiology and disappointing results from conventional IBS medications,the treatment of IBS is challenging and use of complementary and alternative medicines especially herbal therapies is increasing.In this paper,electronic databases including PubMed,Scopus,and Cochrane library were searched to obtain any in vitro,in vivo or human studies evaluating single or compound herbal preparations in the management of IBS.One in vitro,3 in vivo and 23 human studies were included and systematically reviewed.The majority of studies are about essential oil of Menta piperita as a single preparation and STW 5 as a compound preparation.Some evaluated herbs such as Curcuma xanthorriza and Fumaria officinalis did not demonstrate any benefits in IBS.However,it seems there are many other herbal preparations such as those proposed in traditional medicine of different countries that could be studied and investigated for their efficacy in management of IBS. | Roja Rahimi Mohammad Abdollahi | 2012 | World Journal of Gastroenterology2012，18，7： | 11 |
| 8 | Modeling industrial thickener using computational fluid dynamics(CFD),a case study:Tailing thickener in the Sarcheshmeh copper mine显示文摘Separation of particles from liquid in the large gravitational tanks is widely used in mining and industrial wastewater treatment process.Thickener is key unit in the operational processes of hydrometallurgy and is used to separate solid from liquid.In this study,population balance models were combined with computational fluid dynamics(CFD)for modeling the tailing thickener.Parameters such as feed flow rate,flocculant dosage,inlet solid percent and feedwell were investigated.CFD was used to simulate the industrial tailing thickener with settled bed of 120 m diameter which is located in the Sarcheshmeh copper mine.Important factor of drag force that defines the rake torque of rotating paddles on the bed was also determined.Two phases turbulence model of Eulerian/Eulerian in accordance with turbulence model ofκ-ε.was used in the steady-state.Also population balance model consists of 15 groups of particle sizes with Luo and Lehr kernel was used for aggregation/breakage kernel.The simulation results showed good agreement with the operational data. | Majid Ebrahimzadeh Gheshlaghi Ataallah Soltani Goharrizi Alireza Aghajani Shahrivar Hadi Abdollahi | 2013 | International Journal of Mining Science and Technology2013，23，6： | 10 |
| 9 | A review of the efficacy of traditional Iranian medicine forinflammatory bowel disease显示文摘The etiology of inflammatory bowel disease(IBD) is not yet known,but many factors such as defects in the immune system,oxidative stress,microbial content in the gastrointestinal tract,nuclear factor(NF)-κB,nitric oxide(NO),cyclooxygenase-2(Cox-2),and leukotriene B4(LB4) are thought to play a role in its pathogenesis.In traditional Iranian medicine(TIM),several medicinal plants are thought to be effective for the treatment of IBD.In this study,information on all of these remedies were derived from all available old sources such as documents or notes and books and were added to the information derived from modern medical databases covering all in vitro,in vivo and clinical trials.For some of these plants,only one or two mechanisms of action have been found such as in Cassia fistula,Lepidium sativum,and Bunium persicum.However,for some plants various mechanisms of action are known.For example,Commiphora mukul is effective in IBD due to its immunomodulatory,antioxidant,and antibacterial properties and it decreases NF-κB,NO and Cox-2.Another herb,Plantago ovata,has immunomodulatory,antioxidant,anti-inflammatory and wound healing activities and decreases NO and LB4.Considering the mechanisms of action of these plants,the combination of some of them may be useful because of their many mechanisms of action such as Pistacia lentiscus,Bunium persicum,Solanum nigrum,Plantago ovata,Boswellia,Solanum nigrum,Plantago ovata and Commiphora mukul.For some of the herbal products used in TIM such as oleogum resin from Commiphora myrrha,seeds of Ocimum basilicum,seeds of Linum usitatissimum,gum resin of Dracaena cinnabari,seeds of Plantago major,seeds of Lallementia royleana,and seeds of Allium porrum,there is no or not enough studies to confirm their benefits in IBD.It is suggested that an evaluation of the effects of these plants on different aspects of IBD should be performed. | Roja Rahimi Mohammad Abdollahi Mohammad Reza Shams-Ardekani | 2010 | World Journal of Gastroenterology2010，16，36： | 10 |
| 10 | Antioxidant therapy in the management of acute,chronic and post-ERCP pancreatitis:A systematic review显示文摘We systematically reviewed the clinical trials which recruited antioxidants in the therapy of pancreatitis and evaluated whether antioxidants improve the outcome of patients with pancreatitis.Electronic bibliographic databases were searched for any studies which investigated the use of antioxidants in the management of acute pancreatitis(AP)or chronic pancreatitis(CP)and in the prevention of post-endoscopic retrograde cholangio-pancreatography(post-ERCP)pancreatitis(PEP)up to February 2009.Twenty-two randomized,placebo-controlled,clinical trials met our criteria and were included in the review.Except for a cocktail of antioxidants which showed improvement in outcomes in three different clinical trials,the results of the administration of other antioxidants in both AP and CP clinical trials were incongruent and heterogeneous.Furthermore,antioxidant therapy including allopurinol and N-acetylcysteine failed to prevent the onset of PEP in almost all trials.In conclusion,the present data do not support a benefit of antioxidant therapy alone or in combination with conventional therapy in the management of AP,CP or PEP.Further double blind,randomized,placebo-controlled clinical trials with large sample size need to be conducted. | Seyed Sajad Mohseni Salehi Monfared Hamed Vahidi Amir Hossein Abdolghaffari Shekoufeh Nikfar Mohammad Abdollahi | 2009 | World Journal of Gastroenterology2009，15，36： | 10 |
| 11 | Systematic review of modulators of benzodiazepine receptors in irritable bowel syndrome:Is there hope?显示文摘Several drugs are used in the treatment of irritable bowel syndrome(IBS) but all have side effects and variable efficacy.Considering the role of the gut-brain axis,immune,neural,and endocrine pathways in the pathogenesis of IBS and possible beneficial effects of benzodiazepines(BZD) in this axis,the present systematic review focuses on the efficacy of BZD receptor modulators in human IBS.For the years 1966 to February 2011,all literature was searched for any articles on the use of BZD receptor modulators and IBS.After thorough evaluation and omission of duplicate data,10 out of 69 articles were included.BZD receptor modulators can be helpful,especially in the diarrhea-dominant form of IBS,by affecting the in? ammatory,neural,and psychologic pathways,however,controversies still exist.Recently,a new BZD receptor modulator,dextof isopam was synthesized and studied in human subjects,but the studies are limited to phase □b of BZDs in IBS,but bearing in mind the concentrationdependent effect of BZDs on cytokines and cell proliferation,future studies using pharmacodynamic and pharmacokinetic approaches are highly recommended. | Pooneh Salari Mohammad Abdollahi | 2011 | World Journal of Gastroenterology2011，17，38： | 9 |
| 12 | 超细晶Al5083合金和碳化硼增强Al5083基复合材料的室温和高温干滑动摩擦磨损行为显示文摘讨论机械球磨Al5083合金和Al5083−5wt.%B4C复合材料在室温和200°C下的摩擦行为和磨损机制。结果表明,由于常温下的氧化磨损,形成可保护试样表面的机械混合层。在室温和80 N载荷下,Al5083和Al5083−5wt.%B4C球磨样品有磨损迹象,但体积磨损量有限,磨损率分别为5.8×10−7和4.4×10−7mm3/(m·N)。在200°C和80 N载荷下,球磨Al5083样品磨损严重,磨损率达10.8×10−7 mm3/(m·N);Al5083−5wt.%B4C样品的磨损较轻,局部出现三体磨损,磨损率为5.3×10−7 mm3/(m·N)。位错钉扎和Hall−Petch理论等强化机制、高硬度和载荷传递效应是决定Al5083−5wt.%B4C复合材料磨损行为的关键因素。另一方面,球磨Al5083样品在200°C下磨损率较高可能与其局部晶粒长大和硬度下降有关。 | Matin SAESSI Ali ALIZADEH Alireza ABDOLLAHI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，1： | 7 |
| 13 | Kinetics of chemical leaching of chalcopyrite from low grade copper ore: behavior of different size fractions显示文摘The kinetics of the chemical leaching of copper from low grade ore in ferric sulfate media was investigated using the constrained least square optimization technique. The experiments were carried out for different particle sizes in both the reactor and column at constant oxidation-reduction potential (Eh), pH values, and temperature. The main copper mineral was chalcopyrite. About 40% of Cu recovery is obtained after 7 d of reactor leaching at 85℃ using -0.5 mm size fraction, while the same recovery is obtained at 75℃ after 24 d. Also, about 23% of Cu recovery is obtained after 60 d of column leaching for +4--8 mm size fraction whereas the Cu recovery is as low as about 15% for +8--12.7 and +12.7--25 mm size fractions. A 4-stage model for chalcopyrite dissolution was used to explain the observed dissolution behaviors. The results show that thick over-layers of sulphur components cause the parabolic behavior of chalcopyrite dissolution and the precipitation of Fe3+ plays the main role in chalcopyrite passivation. In the case of coarse particles, transformation from one stage to another takes a longer time, thus only two stages including the initial reaction on fresh surfaces and S0 deposition are observed. | H. Naderi M. Abdollahy N. Mostoufi M.J. Koleini S.A. Shojaosadati Z. Manafi | 2011 | International Journal of Minerals,Metallurgy and Materials2011，18，6： | 6 |
| 14 | Antioxidant therapy in acute,chronic and post-endoscopic retrograde cholangiopancreatography pancreatitis:An updated systematic review and meta-analysis显示文摘AIM:To investigate the efficacy and adverse effects of antioxidant therapy in acute pancreatitis(AP),chronic pancreatitis(CP) and post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP).METHODS:Pub Med,Scopus,Google Scholar,Cochrane library database,and Evidence-based medicine/clinical trials published before August 2014 were searched. Clinical and laboratory outcomes of randomized trials of antioxidant therapy in patients with AP,CP and PEP were included. The methodological quality of the trials was assessed by the Jadad score based on the description of randomization,blinding,and dropouts(withdrawals). The results of the studies were pooled and meta-analyzed to provide estimates of the efficacy of antioxidant therapy.RESULTS:Thirty four trials out of 1069 potentially relevant studies with data for 4898 patients wereeligible for inclusion. Antioxidant therapy significantly reduced the length of hospital stay in AP patients {mean difference-2.59 d(95%CI:-4.25-(-0.93)],P = 0.002}. Although,antioxidant therapy had no significant effect on serum C reactive protein(CRP) after 5-7 d in AP patients [mean difference-9.57(95%CI:-40.61-21.48,P = 0.55],it significantly reduced serum CRP after 10 d {mean difference-45.16 [95%CI:-89.99-(-0.33)],P = 0.048}. In addition,antioxidant therapy had no significant effect on CP-induced pain [mean difference-2.13(95%CI:-5.87-1.6),P = 0.26]. Antioxidant therapy had no significant effects on the incidence of all types of PEP [mean difference 1.05(95%CI:0.74-1.5),P = 0.78],severe PEP [mean difference 0.92(95%CI:0.43-1.97),P = 0.83],moderate PEP [mean difference 0.82(95%CI:0.54-1.23),P = 0.33],and mild PEP [mean difference 1.33(95%CI:0.99-1.78),P = 0.06]. Furthermore,while antioxidant therapy had no significant effect on serum amylase after less than 8 h sampling [mean difference-20.61(95%CI:-143.61-102.39),P = 0.74],it significantly reduced serum amylase close to 24-h sampling {mean difference-16.13 [95%CI:-22.98-(-9.28)],P < 0.0001}.CONCLUSION:While there is some evidence to support antioxidant therapy in AP,its effect on CP and PEP is still controversial. | Maziar Gooshe Amir Hossein Abdolghaffari Shekoufeh Nikfar Parvin Mahdaviani Mohammad Abdollahi | 2015 | World Journal of Gastroenterology2015，21，30： | 6 |
| 15 | 糖尿病神经病变与视网膜病变的相关性研究(英文)显示文摘目的:探讨糖尿病患者发生微循环障碍时,外周神经病变(DPN)与视网膜病变之间是否有相关性,及二者在2型糖尿病中的危险指数。方法:本研究包括100例(男性51例,女性49例)门诊的糖尿病患者,均为非胰岛素依赖的糖尿病患者(NIDDM),观察患者的外周神经病变及视网膜病变进展情况,随访时间18mo。结果:视网膜病变的患者78.1%同时有外周神经病变,患有外周神经病变的患者79.1%同时有视网膜病变,统计学分析表明外周神经病变与视网膜病变之间并没有明显的相关性。但是,90.9%患有增殖性糖尿病视网膜病变的患者同时有外周神经病变,而27.8%患有视网膜病变的患者同时有外周神经病变,单因素及多因素logistic回归分析均表明它们之间有明显的相关性(r=0.42,P=0.02)。结论:严重的糖尿病视网膜病变与糖尿病性神经病变有相关性。本研究表明糖尿病神经病变可作为糖尿病视网膜病变进程的预警信号,出现神经病变的患者需要更细致广泛的眼科检查,特别是对于病程较长的糖尿病患者。 | Ali Abdollahi Sasan Moghimi Abdolreza Tabasi Mohammad Taher Rajabi Baharak Sabet | 2007 | 国际眼科杂志2007，7，5： | 6 |
| 16 | 从含Cu,Ni,Fe和Zn离子的Sarcheshmeh铜矿合成及工业溶液中萃取和反萃Cu和Ni(英文)显示文摘以D2EHPA、LIX 984、Cyanex 302、Chemorex CP 150和Acorga 5774为萃取剂,煤油为稀释剂,对取自Sarcheshmeh铜矿含Cu(770mg/L)、Ni(3200mg/L)、Fe(800mg/L)和Zn(200mg/L)的合成及工业溶液中Cu和Ni的萃取与反萃进行全面研究。萃取阶段考虑的影响因素有混合速度和时间、萃取剂浓度、p H和温度。此外,采用不同浓度的各种无机和有机酸(硫酸、盐酸、硝酸和柠檬酸)对Cu和Ni进行反萃。结果表明,在时间为3 min、混合速度为500 r/min、温度为28℃以及A/O比为1:1的条件下,Cu和Ni的萃取率最高。此外,用10%(v/v)LIX984可有效萃取Cu,而用30%(v/v)Cyanex 302可有效萃取Ni。萃取Cu和Ni的最佳p H分别为2~3和4~5。从含Ni、Cu、Zn和Fe离子的合成及工业溶液中可选择性萃取Cu和Ni,其萃取率分别为85%、93%和77%、82%。最佳条件实验结果表明,合成及工业溶液中Ni的反萃率达96%,Cu的反萃率为93%。最后,分别用D2EHPA、LIX 984和Cyanex 3023种萃取剂分3个阶段萃取Zn、Fe、Cu和Ni 4种元素,而杂质萃取率最低。 | Amirhossein SOEEZI Hadi ABDOLLAHI Sied Ziaedin SHAFAEI Esmaeil RAHIMI | 2020 | Transactions of Nonferrous Metals Society of China2020，30，2： | 6 |
| 17 | Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways显示文摘Inflammatory bowel disease(IBD)refers to a group of disorders characterized by chronic inflammation of the gastrointestinal(GI)tract.The elevated levels of nitric oxide(NO)in serum and affected tissues;mainly synthesized by the inducible nitric oxide synthase(iNOS)enzyme;can exacerbate GI inflammation and is one of the major biomarkers of GI inflammation.Various natural and synthetic agents are able to ameliorate GI inflammation and decrease iNOS expression to the extent comparable with some IBD drugs.Thereby,the purpose of this study was to gather a list of natural or synthetic mediators capable of modulating IBD through the NO pathway.Electronic databases including Google Scholar and PubMed were searched from 1980 to May 2018.We found that polyphenols and particularly flavonoids are able to markedly attenuate NO production and iNOS expression through the nuclear factorκB(NF-κB)and JAK/STAT signaling pathways.Prebiotics and probiotics can also alter the GI microbiota and reduce NO expression in IBD models through a broad array of mechanisms.A number of synthetic molecules have been found to suppress NO expression either dependent on the NF-κB signaling pathway(i.e.,dexamethasone,pioglitazone,tropisetron)or independent from this pathway(i.e.,nicotine,prednisolone,celecoxib,β-adrenoceptor antagonists).Co-administration of natural and synthetic agents can affect the tissue level of NO and may improve IBD symptoms mainly by modulating the Toll like receptor-4 and NF-κB signaling pathways. | Aida Kamalian Masoud Sohrabi Asl Mahsa Dolatshahi Khashayar Afshari Shiva Shamshiri Nazanin Momeni Roudsari Saeideh Momtaz Roja Rahimi Mohammad Abdollahi Amir Hossein Abdolghaffari | 2020 | World Journal of Gastroenterology2020，26，24： | 5 |
| 18 | Fuel efficient model predictive control strategies for a group of connected vehicles incorporating vertical vibration显示文摘This paper presents a decentralized fuel efficient model predictive control(MPC) strategy for a group of connected vehicles incorporating vertical vibration. To capture the vehicle vibration dynamics, the dynamics of the suspension system is integrated with the longitudinal dynamics of the vehicle. Furthermore, a MPC framework with finite time horizon is formulated to calculate the optimal velocity profile that compromises fuel economy, mobility and ride comfort for every individual vehicle with the safety and physical constraints considered. In the MPC framework, the target velocity is calculated using signal phase and timing(SPAT)information to reduce the number of stoppage at red lights, and the vertical acceleration is calculated parallel to the calculation of the fuel consumption. The MPC optimal problem is solved with fast-MPC approach which enhances the computational efficiency via exploiting the structure of the control system and approximate methods. Simulation studies are conducted over different SPATs and connectivity penetration rates and the results validate the advantages of the proposed control architecture. | QIAN LiJun QIU LiHong CHEN Peng ABDOLLAHI Zoleikha PISU Pierluigi | 2017 | Science China(Technological Sciences)2017，60，11： | 5 |
| 19 | Role of international criteria in the diagnosis of autoimmune hepatitis显示文摘AIM: To study the clinical and laboratory characteristics of autoimmune hepatitis (AIH), and compare them with International Autoimmune Hepatitis Group (IAHG) criteria. METHODS: Sixty consecutive patients with AIH attended the University Clinic at Tabriz University of Medical Sciences, Iran for a 12mo period and were assessed in a case series study. Serological and biochemical evaluations were carried out in all patients. Autoantibodies, such as antinuclear antibody (ANA), anti-smooth muscle antibody (ASMA), anti-liver-kidney microsomal antibody (ALKM-1) type 1, and perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) were evaluated in these patients. A liver biopsy was performed after diagnosis of the disease. Patients were evaluated in terms of their signs and symptoms, and laboratory results and the degree to which they corresponded with the diagnostic criteria of IAHG. In this study, both a comprehensive diagnostic scoring system and a simplified diagnostic scoring system were employed for AIH.RESULTS: Sixty patients, 2-0 male, 40 female, mean age 39.45 ± 17.50 years, participated in the study. Treatment began immediately after enrolment into the study. The percent distribution of the study population into definite and probable did not change after the treatment. The most common symptoms in descending order were fatigue (100%), icter (66.7%), abdominal discomfort (33.3%), abdominal distension (2-8.3%), dark urine (2-3.3%), edema (2-3.3%), hematemesis (2-0.0%), pruritus (2-0.0%), melena (11.7%) and pale stool (10.0%). At the physical examination, splenomegaly, ascites, hepatomegaly, epigastric tenderness and an abdominal mass were found in 50.0%, 16.7%, 13.3%, 5.0% and 3.3% of patients, respectively. Hypergammaglobulinemia was detected in 95.0% of cases. ALKM-1, P-ANCA, ANA and ASMA were positive in 71.4%, 66.7%, 42-.4% and 19.4% of cases, respectively. Portal hypertensive gastropathy (45.0%), esophageal varices (41.7%) and cirrhosis (40.0%) were the most prevalent complications of AIH, and there was no evidence of primary sclerosing cholangitis, ulcerative colitis and overlap syndrome in these patients. According to IAHG criteria, 80.0% of cases had a definite diagnosis, 15.0% had a probable diagnosis and 5.0% had no AIH. The percent distribution of the study population into definite, probable and no AIH did not change after using the simplified diagnostic scoring system for AIH. CONCLUSION: This research showed that the majority of cases in our study were appropriately diagnosed according to the IAHG criteria and simplified scoring system. Thus, these criteria are very useful. | Mohammad Reza Abdollahi Mohammad Hossein Somi Esmaeil Faraji | 2013 | World Journal of Gastroenterology2013，19，23： | 5 |
| 20 | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis显示文摘AIM: To investigate the beneficial effect of the combination of butyrate, Lactobacillus casei, and L-carnitine in a rat colitis model.METHODS: Rats were divided into seven groups. Fourgroups received oral butyrate, L-carnitine, Lactobacillus casei and the combination of three agents for 10 consecutive days. The remaining groups included negative and positive controls and a sham group. Macroscopic, histopathological examinations, and biomarkers such as tumor necrosis factor-alpha(TNF-α) and interlukin-1β(IL-1β), myeloperoxidase(MPO), thiobarbituric acid reactive substances(TBARS), and ferric reduced ability of plasma(FRAP) were determined in the colon.RESULTS: The combination therapy exhibited a significant beneficial effect in alleviation of colitis compared to controls. Overall changes in reduction of TNF-α(114.66 ± 18.26 vs 171.78 ± 9.48 pg/mg protein, P < 0.05), IL-1β(24.9 ± 1.07 vs 33.06 ± 2.16 pg/mg protein, P < 0.05), TBARS(0.2 ± 0.03 vs 0.49 ± 0.04 μg/mg protein, P < 0.01), MPO(15.32 ± 0.4 vs 27.24 ± 3.84 U/mg protein, P < 0.05), and elevation of FRAP(23.46 ± 1.2 vs 15.02 ± 2.37 μmol/L, P < 0.05) support the preference of the combination therapy in comparison to controls. Although the monotherapies were also effective in improvement of colitis markers, the combination therapy was much better in improvement of colon oxidative stress markers including FRAP, TBARS, and MPO.CONCLUSION: The present combination is a suitable mixture in control of experimental colitis and should be trialed in the clinical setting. | Mahsa Moeinian Seyedeh Farnaz Ghasemi-Niri Shilan Mozaffari Amir Hossein Abdolghaffari Maryam Baeeri Mona Navaea-Nigjeh Mohammad Abdollahi | 2014 | World Journal of Gastroenterology2014，20，31： | 5 |
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